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Brodalumab

CAS No.
1174395-19-7
Chemical Name:
Brodalumab
Synonyms
Brodalumab;Brodalumab (anti-IL17RA);LP 0160|||KHK-4827|||AMG-827;Research Grade Brodalumab(DHJ38901)
CBNumber:
CB94845996
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD01864808
MOL File:
Mol file
Last updated:2024-07-02 08:55:42

Brodalumab Properties

storage temp. Store at -20°C
form Liquid
color Colorless to light yellow
FDA UNII 6ZA31Y954Z
ATC code L04AC12

Pharmacokinetic data

Excreted unchanged in urine Minimal
Volume of distribution 7.24 Litres
Biological half-life 10.9 days

Brodalumab Chemical Properties,Uses,Production

Uses

Brodalumab has been used in trials studying the treatment of Asthma, Psoriasis, Crohn's Disease, Psoriatic Arthritis, and Rheumatoid Arthritis. Brodalumab was FDA approved in February, 2017 as Siliq for the treatment of moderate-to-severe plaque psoriasis.

Clinical Use

Human monoclonal immunoglobulin IgG2 antibody:

Treatment of moderate to severe plaque psoriasis

Drug interactions

Potentially hazardous interactions with other drugs
Avoid with live vaccines.

Metabolism

Brodalumab is expected to be degraded into small peptides and amino acids via catabolic pathways in a manner similar to endogenous IgG. Brodalumab is expected to be mainly eliminated via catabolism and hepatic impairment is not expected to influence clearance.

Brodalumab Preparation Products And Raw materials

Raw materials

Preparation Products

Brodalumab Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9707 58
Guangzhou Hongyuan Chemical Co.,Ltd 15817493340 981810490@qq.com China 1565 58
Wuhan Chemstan Biotechnology Co., Ltd. 027-65317797 15926423062 422450190@qq.com China 10332 58
AntibodySystem 17762345272 18162686757 biolab-reagents@atagenix.com China 9819 58
Wuhan Jingkangen Biomedical Technology Co., Ltd 13720134139 13720134139 orders@jknbiochem.com China 5402 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 market@aladdin-e.com China 48465 58
Changsha Fuzhen Biotechnology Co.,LTD 0731-18670069 18670069958 184792226@qq.com China 3195 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28091 58
Brodalumab Research Grade Brodalumab(DHJ38901) Brodalumab (anti-IL17RA) LP 0160|||KHK-4827|||AMG-827 1174395-19-7