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2-CHLOROLEPIDINE

2-CHLOROLEPIDINE Structure
2-CHLOROLEPIDINE structure
CAS No.
634-47-9
Chemical Name:
2-CHLOROLEPIDINE
Synonyms
AKOS BB-6898;Chlorolepidine;3-chlorolepidine;2-CHLOROLEPIDINE;AKOS BBS-00000215;Lepidine, 2-chloro-;2-Chlorolepidine >OTAVA-BB BB0116110026;2-chloro-4-methyl-quinolin;2-CHLORO-4-METHYLQUINOLINE
CBNumber:
CB9663910
Molecular Formula:
C10H8ClN
Molecular Weight:
177.63
MDL Number:
MFCD00006742
MOL File:
634-47-9.mol
MSDS File:
SDS
Last updated:2023-04-27 16:27:43
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2-CHLOROLEPIDINE Properties

Melting point 55-58 °C(lit.)
Boiling point 296 °C(lit.)
Density 1.1810 (rough estimate)
refractive index 1.6224 (estimate)
Flash point 296°C
storage temp. Inert atmosphere,Room Temperature
pka 0.98±0.50(Predicted)
form powder to crystal
color White to Almost white
BRN 118333
CAS DataBase Reference 634-47-9(CAS DataBase Reference)
FDA UNII 2U5ATH9EJR
NIST Chemistry Reference Quinoline, 2-chloro-4-methyl-(634-47-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-36-24/25
WGK Germany  3
HS Code  29334900
NFPA 704
1
2 0

2-CHLOROLEPIDINE price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C0191 2-Chlorolepidine >98.0%(GC) 634-47-9 5g $44 2024-03-01 Buy
TCI Chemical C0191 2-Chlorolepidine >98.0%(GC) 634-47-9 25g $146 2024-03-01 Buy
Alfa Aesar H26504 2-Chloro-4-methylquinoline, 99% 634-47-9 5g $47.65 2024-03-01 Buy
Alfa Aesar H26504 2-Chloro-4-methylquinoline, 99% 634-47-9 25g $151.65 2024-03-01 Buy
TRC C587370 2-Chloro-4-methyl-quinoline 634-47-9 5G $55 2021-12-16 Buy
Product number Packaging Price Buy
C0191 5g $44 Buy
C0191 25g $146 Buy
H26504 5g $47.65 Buy
H26504 25g $151.65 Buy
C587370 5G $55 Buy

2-CHLOROLEPIDINE Chemical Properties,Uses,Production

Description

4-Methyl-2-chloro-quinoline is an organic intermediate. It has been reported that it can be used to prepare graphite electrodes based on CrO-FeO-PbO and quinoline modified and a modified vermiculite adsorbent for the adsorption and removal of benzene in chemical wastewater.

Preparation

The mixture of 2-hydroxy-4-methylquinoline and phosphorus oxychloride was heated to 80-85°C. After the solid was completely dissolved, the mixture was poured into ice water, the mixture was extracted with ether, and the ether extract was distilled out of ether. Afterwards, carry out vacuum distillation, collect 132-135 ℃ (0.4kPa) fraction, namely 2-chloro-4-methylquinoline. For further purification, petroleum ether (boiling point 40-50°C) can be used for recrystallization, and the yield is 86%-89%.

Chemical Properties

white to light yellow crystal powder

Uses

2-Chloro-4-methyl-quinoline is a useful synthetic intermediate. It is an intermediate used to synthesize 4-Methyl-2-(1-piperidinyl)-quinoline (M320715) which is a potent inhibitor of TRPC4 channels, responsible for various stimulation, muscle response due to interaction with the environment. 2-Chloro-4-methyl-quinoline is also considered as a cyanine dye.

Synthesis Reference(s)

Journal of the American Chemical Society, 63, p. 2367, 1941 DOI: 10.1021/ja01854a016
Organic Syntheses, Coll. Vol. 3, p. 194, 1955

2-CHLOROLEPIDINE synthesis

4053-40-1
634-47-9
Synthesis of 2-CHLOROLEPIDINE from 4-Methylquinoline 1-oxide

2-CHLOROLEPIDINE Preparation Products And Raw materials

Raw materials

2-HYDROXY-4-METHYLQUINOLINE Phosphorus oxychloride

Preparation Products

4-METHYL-2-MORPHOLINOQUINOLINE 4-METHYLQUINOLIN-2-THIONE 4-METHYL-2-PIPERAZIN-1-YL-QUINOLINE 2-Chloro-4-Methylquinolin-8-aMine

2-CHLOROLEPIDINE Suppliers

Global( 181)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29884 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 17322 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17365 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34553 58
Win-Win chemical CO., Limited 		+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14394 58
Hebei Zhanyao Biotechnology Co. Ltd 		15369953316 +8615369953316 admin@zhanyaobio.com China 2123 58
Supplier Advantage
career henan chemical co 		58
Accela ChemBio Inc. 		58
Hubei xin bonus chemical co. LTD 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
SIMAGCHEM CORP 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Win-Win chemical CO., Limited 		58
Hebei Zhanyao Biotechnology Co. Ltd 		58

View Lastest Price from 2-CHLOROLEPIDINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-CHLOROLEPIDINE pictures 2022-03-07 2-CHLOROLEPIDINE
634-47-9
 US $1.10 / g 1g 99.00% 100 Tons Dideu Industries Group Limited
2-CHLOROLEPIDINE pictures 2021-10-15 2-CHLOROLEPIDINE
634-47-9
 US $10.00 / KG 1KG 99% 20 Tons Hebei Zhanyao Biotechnology Co. Ltd
2-CHLOROLEPIDINE pictures 2019-07-06 2-CHLOROLEPIDINE
634-47-9
 US $1.00 / kg 1kg 98% 100KG Career Henan Chemical Co

2-CHLOROLEPIDINE Spectrum

2-CHLOROLEPIDINE(634-47-9)MS2-CHLOROLEPIDINE(634-47-9)1HNMR2-CHLOROLEPIDINE(634-47-9)13CNMR2-CHLOROLEPIDINE(634-47-9)IR12-CHLOROLEPIDINE(634-47-9)IR22-CHLOROLEPIDINE(634-47-9)Raman

634-47-9(2-CHLOROLEPIDINE)Related Search:

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6-BROMO-2-CHLOROQUINOLINE-4-CARBOXYLIC ACID, 97 4-methylquinoline 2-Chloroquinoline IFLAB-BB F0016-0970 METHYL 6-BROMO-2-CHLOROQUINOLINE-4-CARBOXYLATE
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6-BROMO-2-CHLORO-4-PHENYLQUINOLINE 2-CHLORO-4,7-DIMETHYLQUINOLINE N,N-Diethyl-2-chloroquinoline-4-carboxamide

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AKOS BBS-00000215 AKOS BB-6898 OTAVA-BB BB0116110026 2-CHLOROLEPIDINE 2-CHLORO-4-METHYLQUINOLINE 2-chloro-4-methyl-quinolin Chlorolepidine 3-chlorolepidine 2-Chloro-4-methylquinoline, 2-Chlorolepidine Lepidine, 2-chloro- 2-Chlorolepidine > Quinoline, 2-chloro-4-methyl- 2-CHLOROLEPIDINE ISO 9001：2015 REACH 634-47-9 Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Haloquinolines Quinolines Alkylquinolines Quinoline&Isoquinoline Alkylquinolines Haloquinolines Quinolines