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ChemicalBook >> CAS DataBase List >>9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER Structure
9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER structure
CAS No.
309260-52-4
Chemical Name:
9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER
Synonyms
PGD2-1-GLYCERYL ESTER;PROSTAGLANDIN D2-1-GLYCERYL ESTER;9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER;Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (5Z,9α,13E,15S)-;Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (5Z,9α,13E,15S)-
CBNumber:
CB9691036
Molecular Formula:
C23H38O7
Molecular Weight:
426.54
MDL Number:
MFCD05863733
MOL File:
309260-52-4.mol
Last updated:2023-05-04 17:34:37
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9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER Properties

solubility DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): .1 mg/ml

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 12015 Prostaglandin D2-1-glyceryl ester ≥95% (as a 9:1 mixture of the 1- and 2-glyceryl esters) 309260-52-4 500μg $62 2024-03-01 Buy
Cayman Chemical 12015 Prostaglandin D2-1-glyceryl ester ≥95% (as a 9:1 mixture of the 1- and 2-glyceryl esters) 309260-52-4 1mg $104 2024-03-01 Buy
Cayman Chemical 12015 Prostaglandin D2-1-glyceryl ester ≥95% (as a 9:1 mixture of the 1- and 2-glyceryl esters) 309260-52-4 5mg $448 2024-03-01 Buy
Cayman Chemical 12015 Prostaglandin D2-1-glyceryl ester ≥95% (as a 9:1 mixture of the 1- and 2-glyceryl esters) 309260-52-4 10mg $576 2021-12-16 Buy
AK Scientific 1561AH 9alpha,15S-Dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oicacid,1-glycerylester 309260-52-4 5mg $537 2021-12-16 Buy
Product number Packaging Price Buy
12015 500μg $62 Buy
12015 1mg $104 Buy
12015 5mg $448 Buy
12015 10mg $576 Buy
1561AH 5mg $537 Buy

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER Chemical Properties,Uses,Production

Description

2-Arachidonoyl glycerol (2-AG; ) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.1,2 Incubation of 2-AG with COX-2 and specific prostaglandin H2 (PGH2; ) isomerases in cell cultures and isolated enzyme preparations results in prostaglandin glycerol ester formation.3 The biosynthesis of PGH, PGD, PGE, PGF, and TXA-2-glyceryl ester compounds have all been documented. In RAW 264.7 cells, PGD2-2-glyceryl ester is the main COX metabolite.3 The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 mixture of the 1- and 2-glyceryl esters in typical aqueous media. While the stability and metabolism of these PG products have been investigated, little is known about their intrinsic biological activity.4

Definition

ChEBI: Prostaglandin D2 1-glyceryl ester is a 1-monoglyceride resulting from the condensation of the carboxy group of prostaglandin D2 with the 1-hydroxy group of glycerol. It has a role as a human metabolite. It is a prostaglandins D, an alicyclic ketone, a 1-monoglyceride and a secondary allylic alcohol. It is functionally related to a prostaglandin D2.

References

1. Sugiura, T., Kodaka, T., Kondo, S., et al. 2-Arachidonoylglycerol, a putative endogenous cannabinoid receptor ligand, induces rapid, transient elevation of intracellular free Ca2+ in neuroblastoma X glioma hybrid NG108-15 cells Biochem. Biophys. Res. Commun. 229,58-64(1996).
2. Sugiura, T., Kodaka, T., Kondo, S., et al. Is the cannabinoid CB1 receptor a 2-arachidonoylglycerol receptor? Structural requirements for triggering a Ca2+ transient in NG108-15 cells J. Biochem. 122(4),890-895(1997).
3. Kozak, K.R., Crews, B.C., Morrow, J.D., et al. Metabolism of the endocannabinoids, 2-arachidonylgycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides J. Biol. Chem. 277(47),44877-44885(2002).
4. Kozak, K.R., Crews, B.C., Ray, J.L., et al. Metabolism of prostaglandin glycerol esters and prostaglandin ethanolamides in vitro and in vivo J. Biol. Chem. 276(40),36993-36998(2001).

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11975 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19696 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58

309260-52-4(9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER)Related Search:

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER PROSTAGLANDIN D2
9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER PGD2-1-GLYCERYL ESTER PROSTAGLANDIN D2-1-GLYCERYL ESTER Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (5Z,9α,13E,15S)- Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (5Z,9α,13E,15S)- 309260-52-4