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Maduramycin ammonium

Maduramycin ammonium structure

CAS No.: 84878-61-5

Chemical Name:: Maduramycin ammonium

Synonyms: Cygro;Maduramycin 1%;Maduramycin 90%;princin ammonoum;Prinicin ammonium;Madumixing ammonium;MADURAMYCIN AMMONIUM;MADURAMICIN AMMONIUM;Madubamycin ammonium;Maduraminic Ammonium

CBNumber:: CB9703623

Molecular Formula:: C47H83NO17

Molecular Weight:: 934.17

MDL Number:: MFCD08273836

MOL File:: 84878-61-5.mol

MSDS File:: SDS

Last updated:2025-04-17 18:22:24

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Maduramycin ammonium Properties

Melting point	173-176 °C
storage temp.	Inert atmosphere,2-8°C
solubility	DMF: 1 mg/ml
form	Solid
color	White to light yellow
FDA 21 CFR	558.4
FDA UNII	5U912U22T2

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Danger

Hazard statements

H300+H310-H319

Precautionary statements

P262-P264-P280-P301+P310-P302+P352+P310-P305+P351+P338

Hazard Codes

T+

Risk Statements

25-27-36

Safety Statements

26-28-36/37-45

RIDADR

UN 2811

WGK Germany

HazardClass

6.1

PackingGroup

III

NFPA 704

	0
4		0

Maduramycin ammonium price More Price(13)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	34069	Maduramicin ammonium VETRANAL?, analytical standard	84878-61-5	100mg	$113	2024-03-01	Buy
TRC	M110000	Maduramicin ammonium	84878-61-5	100mg	$135	2021-12-16	Buy
Usbiological	257343	Maduramicin ammonium	84878-61-5	10mg	$326	2021-12-16	Buy
American Custom Chemicals Corporation	PST0000321	MADURAMICIN AMMONIUM 95.00%	84878-61-5	100MG	$704.55	2021-12-16	Buy
American Custom Chemicals Corporation	PST0000321	MADURAMICIN AMMONIUM 95.00%	84878-61-5	1G	$1593.9	2021-12-16	Buy

Product number	Packaging	Price	Buy
34069	100mg	$113	Buy
M110000	100mg	$135	Buy
257343	10mg	$326	Buy
PST0000321	100MG	$704.55	Buy
PST0000321	1G	$1593.9	Buy

Maduramycin ammonium Chemical Properties,Uses,Production

Description

Maduramycin ammonium salt is a white crystalline powder with a melting point of 165-167°C. It is insoluble in water and soluble in organic solvents. Because of its broad anticoccidial spectrum and not easy to develop drug resistance, it is widely used. The dosage is very small. At present, our country stipulates that the amount of maduramycin ammonium salt added to the feed for preventing chicken coccidiosis is 5mg/kg.

Chemical Properties

White Solid

Uses

Polyether antibiotic chemically related to the lonomycins. Coccidiostat

Uses

Maduramicin ammonium is prepared from maduramicin by taking advantage of the acidic carboxylic acid which ionises and readily forms the salt in ammonium hydroxide solutions. The ammonium salt is the preferred formulation in animals to prevent coccidiosis and to promote growth. Maduramicin is also active against Treponema and Cryptosporidium. Maduramicin is an ionophore, forming complexes with monovalent cations, with a higher affinity for K+ than Na+.

Uses

Maduramcin ammonium is prepared from maduramicin by taking advantage of the acidic carboxylic acid which ionises and readily forms the salt in ammonium hydroxide solutions. The ammonium salt is the preferred formulation in animals to prevent coccidiosis and to promote growth. Maduramicin is also active against Treponema and Cryptosporidium. Maduramicin is an ionophore, forming complexes with monovalent cations, with a higher affinity for K+ than Na+.

Definition

ChEBI: Maduramicin is a glycoside.

in vivo

Animal Model:	ICR mouse (Maduramicin-induced rhabdomyolysis model)^[3]
Dosage:	3.5, 7 mg/kg
Administration:	Oral gavage (p.o.), once daily for 7 days
Result:	Significantly reduced body weight, increased AST, ALT, LDH, BUN, and CK levels; Caused that liver exhibited vacuolar degeneration, kidney showed renal tubular epithelial cell shedding, and myocardial and skeletal muscle fibers were disorganized and partially lysed.

Animal Model:	Wistar rats (Maduramicin-induced skeletal muscle injury model)
Dosage:	1.75, 3.5, 7 mg/kg
Administration:	Oral gavage (p.o.), once daily for 7 days
Result:	Dose-dependently increased LC3-II and p62 protein levels in skeletal muscle, indicating impaired autophagic flux; Upregulated eIF2α phosphorylation and ATF4 expression, activating endoplasmic reticulum stress; Increased AMPK phosphorylation, suggesting activation of the AMPK signaling pathway.

Maduramycin ammonium Preparation Products And Raw materials

Raw materials

Preparation Products

Maduramycin ammonium Suppliers

Global( 255)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615531157085	abby@chuanghaibio.com	China	8808	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5868	58
shandong perfect biotechnology co.ltd	+86-53169958659 +86-13153181156	sales@sdperfect.com	China	294	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+86-17396673057	linda@tnjone.com	China	1143	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21628	55
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Cangzhou Wanyou New Material Technology Co.,Ltd	18631714998	sales@czwytech.com	CHINA	904	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6383	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
shandong perfect biotechnology co.ltd	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hubei Jusheng Technology Co.,Ltd.	58
Cangzhou Wanyou New Material Technology Co.,Ltd	58
Xiamen AmoyChem Co., Ltd	58
Shandong chuangyingchemical Co., Ltd.	58
BOC Sciences	58

View Lastest Price from Maduramycin ammonium manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-23	Maduramycin ammonium 84878-61-5	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-04-02	Maduramycin Ammonium 84878-61-5	US $0.00 / kg	1kg	99%	1000kg	Shaanxi TNJONE Pharmaceutical Co., Ltd
2025-03-21	Maduramycin Ammonium 84878-61-5	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mujin Biotechnology Co.,Ltd

Maduramycin ammonium
84878-61-5
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

Maduramycin Ammonium
84878-61-5
US $0.00 / kg
99%
Shaanxi TNJONE Pharmaceutical Co., Ltd

Maduramycin Ammonium
84878-61-5
US $0.00 / KG
99%
Hebei Mujin Biotechnology Co.,Ltd

84878-61-5(Maduramycin ammonium)Related Search:

Ammonium acetate Ammonium sulfate Ammonium chloride Molybdic acid Ammonium dihydrogen phosphate

Behenyl Trimethyl Ammonium Chloride Ammonium hydroxide Ammonium carbonate Ammonium nitrate Maduramicin

MADURAMICIN Hydrolysis polyacrylonitrile,ammonium salt AMMONIUM Maduramycin ammonium MADURAMICIN AMMONIUM 1%

1% Maduramicin Premix Maduramycin Ammonium 90%

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Maduramincin ammonium Maduramicin ammonium premix 2H-Pyran-2-acetic acid, 6-(1R)-1-(2S,5R,7S,8R,9S)-2-(2S,2R,3S,5R,5R)-3-(2,6-dideoxy-3,4-di-O-methyl-.beta.-L-arabino-hexopyranosyl)oxyoctahydro-2-methyl-5-(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl2,2-bifuran-5-yl-9-hydroxy-2,8-dimet MADURAMICIN AMMONIUM 90% princin ammonoum MADURAMYCIN AMMONIUM Decocci (Maduramcin ammonium premix) (2R,3S,4S,5R,6S)-6-[(1R)-1-[(2S,5R,7S,8R,9S)-2-[(2S,2'R,3'S,5R,5'R)-3'-[(2,6-Dideoxy-3,4-di-O-methyl-b-L-arabino-hexopyranosyl)oxy]octahydro-2-methyl-5'-[(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]ethyl]tetrahydro-2-hydroxy-4,5-dimethoxy-3-methyl-2H-pyran-2-acetic acid monoammonium salt maduramicin ammonoium Maduramicin a, Monoammonium Salt maduramycin ammonium premix MaduraMicin α, MonoaMMoniuM Salt MaduraMycin 1% HOUSE STANDARD CL 259971, MaduraMycin sodiuM MADURAMICIN AMMONIUM MADURAMICIN AMMONIUM SALT Madubamycin ammonium Maduraminic Ammonium Cygro Prinicin ammonium Maduramycin 1% Maduramycin 90% Maduramycin ammonium salt Maduramicin Ammonium Standard Maduramycin ammonium USP/EP/BP MaduraMicin AMMoniuM PreMix USP/EP/BP Maduramycin ammonium 2% on corn cob Ammonium 2-((2R,3S,4S,5R,6S)-6-((R)-1-((2S,5R,7S,8R,9S)-2-((2S,2'R,3'S,5R,5'R)-3'-(((2R,4S,5S,6S)-4,5-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5'-((2S,3S,5R,6S)-6-hydroxy-3,5,6-trimethyltetrahydro-2H-pyran-2-yl)-2-methyloctahydro-[2,2'-bifuran]-5-yl)-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl)ethyl)-2-hydroxy-4,5-dimethoxy-3-methyltetrahydro-2H-pyran-2-yl)acetate Ammonium 2-((2R,3S,4S,5R,6S)-6-((R)-1-((2S,5R,7S,8R,9S)-2-((2S,2'R,3'S,5R,5'R)-3'-(((2R,4S,5S,6S)-4,5-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5'-((2S,3S,5R,6S)-6-hydroxy-3,5,6-trimethyltetrahydro-2H-pyran-2-yl)-2-methyloctahydro-[2,2'-bifuran]-5-y Maduramicin ammoniumQ: What is Maduramicin ammonium Q: What is the CAS Number of Maduramicin ammonium Q: What is the storage condition of Maduramicin ammonium Q: What are the applications of Maduramicin ammonium TIANFUCHEM--84878-61-5---Maduramycin ammonium CA14670000 Maduramicin ammonium Madumixing ammonium Maduramicin ammonium, 10 mM in DMSO 84878-61-5 C47H80O17NH3 C47H83NO17 C47H79O17NH4 C47H80O17H3N API's Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals Active Pharmaceutical Ingredients 84878-61-5