AROTINOLOL HCL
- CAS No.
- 68377-91-3
- Chemical Name:
- AROTINOLOL HCL
- Synonyms
- ARL;s596;Almarl;Acemail;Astonil;Anasirol;thiazolehcl;AROTINOLOL HCL;AROTINOLOL HYDROCHLORIDE;AROTINOLOL HCL USP/EP/BP
- CBNumber:
- CB9723043
- Molecular Formula:
- C15H22ClN3O2S3
- Molecular Weight:
- 408
- MDL Number:
- MFCD00941421
- MOL File:
- 68377-91-3.mol
- MSDS File:
- SDS
| Melting point | 234-235.5° (dec) |
|---|---|
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| Water Solubility | Practically insoluble in water |
| form | powder to crystal |
| color | White to Orange to Green |
| Merck | 14,791 |
| FDA UNII | 9DOI1HT306 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 | |||||||||
| RIDADR | UN 2811 6.1/PG III | |||||||||
| RTECS | XM8301000 | |||||||||
| HS Code | 2934.99.3000 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| Toxicity | LD50 in mice (mg/kg): 86 i.v., >360 i.p., >5000 orally (Hara) | |||||||||
| NFPA 704 |
|
AROTINOLOL HCL price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A3145 | Arotinolol Hydrochloride >98.0%(HPLC)(T) | 68377-91-3 | 50mg | $126 | 2024-03-01 | Buy |
| TCI Chemical | A3145 | Arotinolol Hydrochloride >98.0%(HPLC)(T) | 68377-91-3 | 250mg | $402 | 2021-12-16 | Buy |
| TRC | A771503 | Arotinolol Hydrochloride | 68377-91-3 | 10mg | $1135 | 2021-12-16 | Buy |
| Chem-Impex | 37622 | Arotinololhydrochloride,98%(HPLC) 98%(HPLC) | 68377-91-3 | 250MG | $445.76 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0016528 | AROTINOLOL HYDROCHLORIDE 95.00% | 68377-91-3 | 5MG | $496.2 | 2021-12-16 | Buy |
AROTINOLOL HCL Chemical Properties,Uses,Production
Description
Arotinolol hydrochloride i s a β-adrenergic blocker with weak α-antagonistic properties, useful in the treatment of hypertension.
Originator
Sumitomo (Japan)
Uses
Arotinolol is both and alpha- and beta-adrenoceptor antagonist and is used to treat essential tremors and hypertension.
Definition
ChEBI: Arotinolol hydrochloride is an aromatic amide and a member of thiophenes.
Manufacturing Process
To a solution of 2-mercapto-4-(5'-carbamoyl-2'-thiophenyl)thiazole, 3.2 g in
20 ml of 0.3 % aqueous sodium hydroxide solution, 1-chloro-3-tbutylaminopropanol,
12.64 g in 20 ml of methanol was added, while the
temperature was maintained at 20°C.
The reaction solution was stirred at room temperature for 4 h, and then
condensed to a half volume in vacuo. The residual solution, added with 100 ml
of water, was extracted with chloroform. The chloroform extract was washed
with water, dried over anhydrous magnesium sulfate and evaporated in vacuo
to give 4.8 g of 2-(3'-t-butylamino-2'-hydroxypropylthio)-4-(5'-carbamoyl-2'-
thiophenyl)thiazole, as crystals, melting point 234°-235.5°C (dec.,
recrystallized from methanol/water).
In practice it is usually used as hydrochloride.
brand name
ALMARL
Therapeutic Function
Beta-adrenergic blocker
AROTINOLOL HCL Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 | sarah@tnjone.com | China | 1143 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21632 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29871 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49476 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17365 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7724 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9639 | 58 |
View Lastest Price from AROTINOLOL HCL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-15 | Arotinolol hydrochloride
68377-91-3
|
US $48.00-162.00 / mg | 99.84% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-04-24 | Arotinolol Hydrochloride
68377-91-3
|
US $0.00 / kg | 1kg | 99% | 1000kg | Shaanxi TNJONE Pharmaceutical Co., Ltd | |
 |
2019-07-06 | AROTINOLOL HCL
68377-91-3
|
US $1.00 / KG | 1G | 98% | 100KG | Career Henan Chemical Co |
-
- Arotinolol hydrochloride
68377-91-3
- US $48.00-162.00 / mg
- 99.84%
- TargetMol Chemicals Inc.
-
- Arotinolol Hydrochloride
68377-91-3
- US $0.00 / kg
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
-
- AROTINOLOL HCL
68377-91-3
- US $1.00 / KG
- 98%
- Career Henan Chemical Co