ChemicalBook >> CAS DataBase List >>Ethoxymethylenemalononitrile
Ethoxymethylenemalononitrile
- CAS No.
- 123-06-8
- Chemical Name:
- Ethoxymethylenemalononitrile
- Synonyms
- 2-(ETHOXYMETHYLENE)MALONONITRILE;2-(Ethoxymethylene)propanedinitrile;ononitriL;ETHOXYMETHYLENEMALONITRILE;(Ethoxymethylene)propanedinitrile;usafkf-10;NSC 27792;USAF KF-10;usafa-9230;USAF a-9230
- CBNumber:
- CB9767407
- Molecular Formula:
- C6H6N2O
- Molecular Weight:
- 122.12
- MDL Number:
- MFCD00001854
- MOL File:
- 123-06-8.mol
- MSDS File:
- SDS
Last updated:2023-08-31 15:30:57
| Melting point | 64-66 °C(lit.) |
|---|---|
| Boiling point | 160 °C12 mm Hg(lit.) |
| Density | 1.2236 (rough estimate) |
| refractive index | 1.4738 (estimate) |
| Flash point | 155 °C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMF, DMSO, Ethanol, Methanol |
| form | Liquid |
| color | Clear colorless to yellow |
| Water Solubility | insoluble |
| BRN | 1634241 |
| InChIKey | OEICGMPRFOJHKO-UHFFFAOYSA-N |
| CAS DataBase Reference | 123-06-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 91PS2PWB1Q |
| NIST Chemistry Reference | Propanedinitrile, (ethoxymethylene)-(123-06-8) |
| EPA Substance Registry System | Propanedinitrile, (ethoxymethylene)- (123-06-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H317-H334 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352 | |||||||||
| Hazard Codes | Xn,T,Xi | |||||||||
| Risk Statements | 22-42/43-23/24/25-43-20/21/22-R42/43-R23/24/25-R22 | |||||||||
| Safety Statements | 22-36/37-45-36/37/39-26-36-24/25-S45-S36/37/39-S26-S22 | |||||||||
| RIDADR | 3439 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | OO3850000 | |||||||||
| F | 21 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29269090 | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,50mg/kg (50mg/kg),National Technical Information Service. Vol. AD277-689, | |||||||||
| NFPA 704 |
|
Ethoxymethylenemalononitrile price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | E6200 | (Ethoxymethylene)malononitrile 98% | 123-06-8 | 100g | $32.84 | 2024-03-01 | Buy |
| Sigma-Aldrich | E6200 | (Ethoxymethylene)malononitrile 98% | 123-06-8 | 25g | $37.8 | 2024-03-01 | Buy |
| TCI Chemical | E0649 | (Ethoxymethylene)malononitrile >98.0%(GC) | 123-06-8 | 25g | $74 | 2024-03-01 | Buy |
| Alfa Aesar | A14412 | Ethoxymethylenemalononitrile, 97+% | 123-06-8 | 25g | $45.65 | 2024-03-01 | Buy |
| Alfa Aesar | A14412 | Ethoxymethylenemalononitrile, 97+% | 123-06-8 | 100g | $99.65 | 2024-03-01 | Buy |
Ethoxymethylenemalononitrile Chemical Properties,Uses,Production
Description
Ethoxymethylenemalononitrile (EMMN) is an orange solid and the melting point of EMMN is 64–66 °C[1].It is an inexpensive reagent. As a functionalized malono-nitrile, it is widely used to synthesize pyrazoles, pyrimidines and a variety of fused heterocyclic systems.
Chemical Properties
Off White to Pale Yellow
Uses
Ethoxymethylene Malononitrile (cas# 123-06-8) is a compound useful in organic synthesis.
Uses
Chemical intermediate.
Preparation
Triethyl orthoformate (67.3 mg, 0.454 mol) and malononitrile (20.0 mg,0.302 mol) were andded to acetic anhydride (77.2 gm, 0.75 moles) and the mixture was refluxed for 4-5 h at 110-140°C. The reaction was monitored by GC. After the reaction is complete, it is cooled to room temperature. Concentrated the mixture at 70°C at reduced pressure to yield crude solid product and the pure product (Ethoxymethylenemalononitrile) was obtained through purified either by vacuum distillation.
Synthesis Reference(s)
Tetrahedron Letters, 10, p. 3279, 1969 DOI: 10.1017/S0009838800024678
References
[1] Faria J, et al. Ethoxymethylenemalononitrile. Synlett , 2013; 24: 0264–0265.
[2] Maurício , et al. Synthesis and antileishmanial evaluation of 1-aryl-4-(4,5-dihydro-1H-imidazol-2-yl)-1H-pyrazole derivatives. Bioorganic & Medicinal Chemistry Letters, 2011; 21: 7451-7454.
Ethoxymethylenemalononitrile Preparation Products And Raw materials
Raw materials
Preparation Products
[4-AMINO-2-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL]METHANOL
4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE
4-AMINO-2-MERCAPTOPYRIMIDINE-5-CARBONITRILE
4-AMINO-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBALDEHYDE
4-AMINO-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBONITRILE
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Global( 394)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou uniringchem Co., Ltd. | +undefined13585446801 | sales@uniringchem.com | China | 68 | 58 |
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18648 | 58 |
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| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21639 | 55 |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9220 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32820 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29886 | 58 |
View Lastest Price from Ethoxymethylenemalononitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-04-26 | Ethoxymethylenemalononitrile
123-06-8
|
US $0.00 / Kg | 1Kg | 99.0% up | 50 tons per month | Xinxiang Hongqi District Houyuan Trading Co.,Ltd | |
 |
2022-02-22 | (Ethoxymethylene)malononitrile
123-06-8
|
US $0.00 / KG | 1KG | 98.0% | 100 tons | Honest Joy Holdings Limited
|
|
 |
2021-07-13 | Ethoxymethylenemalononitrile
123-06-8
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Ethoxymethylenemalononitrile
123-06-8
- US $0.00 / Kg
- 99.0% up
- Xinxiang Hongqi District Houyuan Trading Co.,Ltd
-
- (Ethoxymethylene)malononitrile
123-06-8
- US $0.00 / KG
- 98.0%
- Honest Joy Holdings Limited
-
- Ethoxymethylenemalononitrile
123-06-8
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
123-06-8(Ethoxymethylenemalononitrile)Related Search:
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Diethyl ethoxymethylenemalonate
ETHOXYLATED COCOAMINE (LATEX STABILIZER)
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ETHOXYMETHYLENEMALONONITRILE
ETHOXYMETHYLENMALONONITRILE
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(ethoxymethylene)-malononitril
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1,1-Dicyano-2-ethoxyethene
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2-Cyano-3-ethoxyacrylonitrile
2-Ethoxy-1,1-ethenedicarbonitrile
a-Cyano-b-ethoxyacrylonitrile
alpha-Cyano-beta-ethoxyacrylonitrile
Ethoxymethylene-malonic acid dinitrile
Malononitrile, (ethoxymethylene)-
USAF a-9230
USAF KF-10
usafa-9230
LABOTEST-BB LT01148236
2-(ETHOXYMETHYLIDENE)MALONONITRILE
PROPANEDINITRILE, (ETHOXYMETHYLENE)-
usafkf-10
ETHOXY METHYLENE MALONOITRILE-
Ethoxy methlenemalononitrile
1-Ethoxy-2,2-dicyanoethylene
Ethoxymethylenemalononitrile ,98%
Ethoxymethylenemalononiyrile
NSC 27792
α-Cyano-β-ethoxyacrylonitrile
Propanedinitrile, 2-(ethoxyMethylene)-
Ethoxy heartland of Methyl Malononitrile
(Ethoxymethylene)malononitrile>
Ethoxy malononitrile
Ethoxymethylenmalononitril
ETHOXYMETHYLENEMALONITRILE
(Ethoxymethylene)propanedinitrile
2-(ETHOXYMETHYLENE)MALONONITRILE
2-(Ethoxymethylene)propanedinitrile
ononitriL
2-(Ethoxymethylene)propanedinitrile (or) 2-(ethoxymethylene)malononitrile
ethoxymethylmalonitrile
2-(ethoxymethylene)malonitrile
123-06-8
C6H6N20
C2H5OCHCCN2
Organic Building Blocks
Nitrogen Compounds
Cyanides/Nitriles
Building Blocks
C6 to C7
Aliphatic Compound
Miscellaneous
API intermediates
Various Intermediates
Intermediates
C6 to C7
Cyanides/Nitriles
Nitrogen Compounds
Pharmaceutical Intermediates