[2H7]-Alfuzosin
![[2H7]-Alfuzosin Structure](CAS/20211123/GIF/1133386-93-2.gif)
- CAS No.
- 1133386-93-2
- Chemical Name:
- [2H7]-Alfuzosin
- Synonyms
- [2H7]-Alfuzosin;N-(3-((4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)tetrahydrofuran-2,3,3,4,4,5,5-d7-2-carboxamide;Alfuzosin D7Q: What is Alfuzosin D7 Q: What is the CAS Number of Alfuzosin D7 Q: What is the storage condition of Alfuzosin D7 Q: What are the applications of Alfuzosin D7
- CBNumber:
- CB98011902
- Molecular Formula:
- C19H27N5O4
- Molecular Weight:
- 389.46
- MDL Number:
- MOL File:
- 1133386-93-2.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| NFPA 704 |
|
[2H7]-Alfuzosin Chemical Properties,Uses,Production
Biological Activity
Alfuzosin-d7 is intended for use as an internal standard for the quantification of alfuzosin by GC- or LC-MS. Alfuzosin is an antagonist of α1-adrenergic receptors (α1-ARs; Kis = 10, 10, and 3.16 nM for α1A-, α1B-, and α1D-ARs, respectively).1 It increases the amount of phenylephrine needed to increase urethral and arterial blood pressure in pithed rats when administered at a dose of 10 mg/kg.2 Formulations containing alfuzosin have been used in the treatment of benign prostatic hyperplasia.
References
1.Kenny, B.A., Miller, A.M., Williamson, I.J.R., et al.Evaluation of the pharmacological selectivity profile of α1 adrenoceptor antagonists at prostatic α1 adrenoceptors: Binding, functional and in vivo studiesBr. J. Pharmacol.118(4)871-878(1996) 2.Martin, D.J., Lluel, P., Pouyet, T., et al.Relationship between the effects of alfuzosin on rat urethral and blood pressures and its tissue concentrationsLife Sci.63(3)169-176(1998)
[2H7]-Alfuzosin Preparation Products And Raw materials
Raw materials
Preparation Products
[2H7]-Alfuzosin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SIMSON PHARMA LIMITED | +91-8291074273 | k.das@simsonpharma.com | India | 228 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | judy.xia@synzest.com | China | 12582 | 58 |
| Shanghai Weiyite Biotechnology Co., Ltd | 15317051735 | josie@wytsci.com | China | 7430 | 58 |
View Lastest Price from [2H7]-Alfuzosin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-05-27 | Alfuzosin-D7
1133386-93-2
|
US $0.00-0.00 / mg | 1mg | 96% | 50mg | Simson Pharma limited |
-
- Alfuzosin-D7
1133386-93-2
- US $0.00-0.00 / mg
- 96%
- Simson Pharma limited