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Siltuximab

Siltuximab Structure
Siltuximab structure
CAS No.
541502-14-1
Chemical Name:
Siltuximab
Synonyms
CNTO-328;Siltuximab;Siltuximab (anti-IL-6);Research Grade Siltuximab(DHC15801)
CBNumber:
CB98080799
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2024-11-19 20:33:22
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Siltuximab Properties

storage temp. Store at -20°C
form Liquid
color Colorless to light yellow
FDA UNII T4H8FMA7IM
NCI Drug Dictionary siltuximab
ATC code L04AC11

Pharmacokinetic data

Volume of distribution 4.5 Litres
Biological half-life 12.1-20.5 days

Siltuximab Chemical Properties,Uses,Production

Uses

Siltuximab it is used for cancer treatment using anti-ICOS antibody if patient has low peripheral T cell receptor clonality.

Clinical Use

Chimeric (human-murine) immunoglobulin G1κ (IgG1κ) monoclonal antibody:
Treatment of multicentric Castleman’s disease (MCD)

Drug interactions

Potentially hazardous interactions with other drugs
Live vaccines: risk of generalised infections - avoid.
Ciclosporin and tacrolimus: monitor levels on
initiation and discontinuation of siltuximab as it may reduce the activity of CYP450.

Metabolism

As siltuximab is a monoclonal antibody, the expected consequence of metabolism is proteolytic degradation to small peptides and individual amino acids, and receptormediated clearance.

Siltuximab Preparation Products And Raw materials

Raw materials

Preparation Products

Siltuximab Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Wuhan Chemstan Biotechnology Co., Ltd. 027-65317797 15926423062 422450190@qq.com China 10359 58
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8011 62
Guangzhou Hongyuan Chemical Co.,Ltd 15817493340 981810490@qq.com China 1566 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62075 58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 17691182729 18161915376 1046@dideu.com China 10007 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24647 58
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 shenlinxing@macklin.cn China 29815 58
Biolab Reagents 027-65279366 18162686757 products@biolabreagent.com China 9818 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Wuhan Chemstan Biotechnology Co., Ltd. 58
ShangHai Biochempartner Co.,Ltd 62
Guangzhou Hongyuan Chemical Co.,Ltd 58
Bide Pharmatech Ltd. 58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 58
TargetMol Chemicals Inc. 58
Shanghai Maclean Biochemical Technology Co., LTD 58
Biolab Reagents 58

View Lastest Price from Siltuximab manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Siltuximab pictures 2024-11-19 Siltuximab
541502-14-1
 US $178.00-648.00 / mg > 95% 10g TargetMol Chemicals Inc.
  • Siltuximab pictures
  • Siltuximab
    541502-14-1
  • US $178.00-648.00 / mg
  • > 95%
  • TargetMol Chemicals Inc.
Siltuximab Research Grade Siltuximab(DHC15801) Siltuximab (anti-IL-6) CNTO-328 541502-14-1