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ChemicalBook >> CAS DataBase List >>1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Structure
1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE structure
CAS No.
869497-75-6
Chemical Name:
1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
Synonyms
VUF 6002;VUF6002 maleate;VUF 6002 maleate;JNJ 10191584 MALEATE;JNJ 10191584 maleate salt;JNJ 10191584 maleate (VUF 6002);1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
CBNumber:
CB9844434
Molecular Formula:
C17H19ClN4O5
Molecular Weight:
394.80956
MDL Number:
MFCD08703121
MOL File:
869497-75-6.mol
Last updated:2023-09-04 15:51:00
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1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Properties

storage temp. Desiccate at RT
solubility DMSO: ≥10mg/mL
form powder
color off-white to light tan

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338-P280a-P304+P340-P405-P501a
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26
WGK Germany  3

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich J3830 JNJ 10191584 maleate salt ≥98% (HPLC) 869497-75-6 5mg $105 2022-05-15 Buy
Sigma-Aldrich J3830 JNJ 10191584 maleate salt ≥98% (HPLC) 869497-75-6 25mg $573 2022-05-15 Buy
Alfa Aesar J65433 JNJ 10191584 maleate 869497-75-6 50mg $229 2021-12-16 Buy
Alfa Aesar J65433 JNJ 10191584 maleate 869497-75-6 10mg $57.2 2021-12-16 Buy
Tocris 2441 JNJ 10191584 maleate ≥99%(HPLC) 869497-75-6 10 $152 2021-12-16 Buy
Product number Packaging Price Buy
J3830 5mg $105 Buy
J3830 25mg $573 Buy
J65433 50mg $229 Buy
J65433 10mg $57.2 Buy
2441 10 $152 Buy

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Chemical Properties,Uses,Production

Uses

A highly selective histamine H4 receptor silent antagonist

Biological Activity

Highly selective histamine H 4 receptor silent antagonist; binds with high affinity to the human H 4 receptor (K i = 26 nM) and is > 540-fold selective over the H 3 receptor (K i = 14.1 μ M). In vitro, inhibits mast cell and eosinophil chemotaxis with IC 50 values of 138 and 530 nM respectively. Orally active in vivo .

storage

room temperature (desiccate)

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Preparation Products And Raw materials

Raw materials

Preparation Products

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Suppliers

Global( 28)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32760 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10522 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Ascent Scientific 4401179829988 customerservice@ascentscientific.co.uk United Kingdom 279 60
VDM Biochemicals 0330-2528181 sales@vdmbio.com United States 510 64
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4217 55
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Aladdin Scientific 		58
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Ascent Scientific 60
VDM Biochemicals 64
Shanghai Lollane Biological Technology Co.,Ltd. 55

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Spectrum

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE(869497-75-6)1HNMR

869497-75-6(1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE)Related Search:

(6-CHLORO-1H-BENZOIMIDAZOL-2-YL)-(4-METHYL-PIPERAZIN-1-YL)-METHANONE 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE 1H-BENZIMIDAZOLE-2-CARBOXALDEHYDE, 5-CHLORO-
JNJ 10191584 MALEATE 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE VUF 6002 JNJ 10191584 maleate salt VUF 6002 maleate VUF6002 maleate JNJ 10191584 maleate (VUF 6002) 869497-75-6 C13H15ClN4OC4H4O4 Other Enzyme Inhibitors and Activators. Histamine Other enzyme inhibitors and activators Histamine receptor