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3-O-Methyldopamine hydrochloride

3-O-Methyldopamine hydrochloride structure

CAS No.: 1477-68-5

Chemical Name:: 3-O-Methyldopamine hydrochloride

Synonyms: 3-METHOXYTYRAMINE;3-METHOXYTYRAMINE HYDROCHLORIDE;3-Methoxy-p-tyraMine Hydrochloride;4-(2-AMINOETHYL)-2-METHOXYPHENOL HYDROCHLORIDE;3-METHOXYTYRAMINE HCL;AURORA KA-7740;TIMTEC-BB SBB003882;TIMTEC-BB SBB000426;RARECHEM AL BW 0216;Dopamine Impurity 2

CBNumber:: CB9853117

Molecular Formula:: C9H13NO2.ClH

Molecular Weight:: 203.67

MDL Number:: MFCD00012902

MOL File:: 1477-68-5.mol

MSDS File:: SDS

Last updated:2025-07-04 15:11:51

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3-O-Methyldopamine hydrochloride Properties

Melting point	213-215 °C(lit.)
Flash point	9℃
storage temp.	-20°C
solubility	DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly)
form	crystalline
color	white to light brown
BRN	3631283
Stability	Stable, but may be light sensitive. Combustible. Incompatible with strong oxidizing agents.
InChI	InChI=1S/C9H13NO2.ClH/c1-12-9-6-7(4-5-10)2-3-8(9)11;/h2-3,6,11H,4-5,10H2,1H3;1H
InChIKey	AWRIOTVUTPLWLF-UHFFFAOYSA-N
SMILES	C1(OC)C(O)=CC=C(CCN)C=1.Cl
FDA UNII	95HIL684P5
UNSPSC Code	41116107
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS06,GHS08

Signal word

Danger

Hazard statements

H225-H301+H311+H331-H370

Precautionary statements

P210-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-37/39

RIDADR

UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany

3-10

HazardClass

IRRITANT

HS Code

29222990

NFPA 704

	0
2		0

3-O-Methyldopamine hydrochloride price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	M-171	3-Methoxytyramine hydrochloride 1.0?mg/mL in methanol (as free base), certified reference material, Cerilliant?	1477-68-5	1mL	$82.5	2024-03-01	Buy
Sigma-Aldrich	65390	3-Methoxytyramine hydrochloride 99% (AT)	1477-68-5	250mg	$169	2024-03-01	Buy
Sigma-Aldrich	65390	3-Methoxytyramine hydrochloride 99% (AT)	1477-68-5	1g	$179	2024-03-01	Buy
Sigma-Aldrich	1225226	Dopamine Related Compound B United States Pharmacopeia (USP) Reference Standard	1477-68-5	30MG	$1290	2024-03-01	Buy
Cayman Chemical	20511	3-methoxy Tyramine (hydrochloride) ≥98%	1477-68-5	50mg	$32	2024-03-01	Buy

Product number	Packaging	Price	Buy
M-171	1mL	$82.5	Buy
65390	250mg	$169	Buy
65390	1g	$179	Buy
1225226	30MG	$1290	Buy
20511	50mg	$32	Buy

3-O-Methyldopamine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

light beige crystalline solid

Uses

3-Methoxy-p-tyramine is a major metabolite of Dopamine (D533780); product of catechol O-methyltransferase.

General Description

3-Methoxytyramine is a metabolite of dopamine, a catecholamine which acts as a neurotransmitter for dopamine receptors and a neurohormone for regulation of numerous brain functions. 3-Methoxytyramine levels can serve as a biomarker for the diagnosis of neuroendocrine tumors such as pheochromocytoma or paraganglioma. This certified solution standard is suitable for LC/MS applications in diagnostic testing, endocrinology, and clinical chemistry.

Biochem/physiol Actions

Major metabolite of dopamine; product of catechol O-methyltransferase.

in vivo

The extracellular DA metabolite 3-Methoxytyramine hydrochloride (3-MT) induces significant behavioral activation in DDD mice. This activity however, is mostly presented as a set of disorganized abnormal movements that includes tremor, head bobbing, straub tail, grooming and abnormal orofacial movements rather than normal forward activity. No effect is observed when 3-Methoxytyramine hydrochloride is infused at doses below 9 μg, at 9 μg and higher doses 3-Methoxytyramine hydrochloride dose-dependently causes transient behavioral activation with a complex set of behaviors. In particular, transient hyperactivity and stereotypy, sniffing, grooming, rearing and mild abnormal involuntary movements (AIMs) at the level of limbs is observed after infusion of 9 μg of 3-Methoxytyramine hydrochloride. Similar behaviors are also observed after 18 μg of 3-Methoxytyramine hydrochloride with the additional appearance of tremor as well as oral and whole body AIMs^[1].

IC 50

Human Endogenous Metabolite

3-O-Methyldopamine hydrochloride synthesis

Synthesis of 3-O-Methyldopamine hydrochloride from Phenol, 2-methoxy-4-(2-nitroethyl)- (9CI)

3-O-Methyldopamine hydrochloride Preparation Products And Raw materials

Raw materials

ZINC Benzyl chloride Nitromethane N,N-Dimethylformamide Potassium carbonate

Triethylamine Palladium 1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE Tetrahydrofuran Lithium Aluminum Hydride

Dichloromethane Benzyl chloroformate Acetic acid Methanol Vanillin

Ammonium acetate 2-(4-Hydroxy-3-methoxyphenyl)acetamide Phenol, 2-methoxy-4-(2-nitroethyl)- (9CI)

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Preparation Products

Dopamine

3-O-Methyldopamine hydrochloride Suppliers

Global( 227)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ShenZhen H&D Pharmaceutical Technology Co., LTD	+8618627948422	sale@hdimpurity.com	China	3681	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	12725	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21622	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29855	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49732	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14459	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58

Supplier	Advantage
ShenZhen H&D Pharmaceutical Technology Co., LTD	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Accela ChemBio Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Win-Win chemical CO., Limited	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58

View Lastest Price from 3-O-Methyldopamine hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-03-04	Dopamine Impurity 4 1477-68-5	US $0.00-0.00 / mg	10mg	98%	500mg	ShenZhen H&D Pharmaceutical Technology Co., LTD
2025-03-04	Dopamine Impurity 4 1477-68-5	US $0.00 / mg	10mg	0.98	10g	ShenZhen H&D Pharmaceutical Technology Co., LTD
2022-05-26	3-O-Methyldopamine hydrochloride 1477-68-5	US $1.10 / g	1g	99.0% Min	100 Tons	Dideu Industries Group Limited

Dopamine Impurity 4
1477-68-5
US $0.00-0.00 / mg
98%
ShenZhen H&D Pharmaceutical Technology Co., LTD

Dopamine Impurity 4
1477-68-5
US $0.00 / mg
0.98
ShenZhen H&D Pharmaceutical Technology Co., LTD

3-O-Methyldopamine hydrochloride
1477-68-5
US $1.10 / g
99.0% Min
Dideu Industries Group Limited

3-O-Methyldopamine hydrochloride Spectrum

3-O-Methyldopamine hydrochloride(1477-68-5)MS 3-O-Methyldopamine hydrochloride(1477-68-5)¹HNMR 3-O-Methyldopamine hydrochloride(1477-68-5)IR1 3-O-Methyldopamine hydrochloride(1477-68-5)Raman

1477-68-5(3-O-Methyldopamine hydrochloride)Related Search:

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3-O-Methyldopanimehydrochloride 3-O-Methyldopamine hydrochloride, p.a. RARECHEM AL BW 0216 TIMTEC-BB SBB000426 TIMTEC-BB SBB003882 3-METHOXY-4-HYDROXY-PHENETHYLAMINE HYDROCHLORIDE 3-METHOXY-4-HYDROXYPHENYLETHYLAMINE, HCL 3-O-METHYLDOPAMINE HYDROCHLORIDE 4-HYDROXY-3-METHOXYPHENETHYLAMINE HYDROCHLORIDE 5-(2-AMINOETHYL)GUAJAKOL HYDROCHLORIDE 3-O-Methyldopamine HCL 5-(2-aminoethyl)guaiacol hydrochloride 3-Methoxy-4-Hydroxyphenethylamine HCl 3-O-Methyldopamine hydrochloride, 99+% 2-(4-HYDROXY-3-METHOXYPHENYL)ETHYLAMINE HYDROCHLORIDE AURORA KA-7740 MethoxytyraMine solution 3-Methoxy-p-tyraMine HCl 3-MethoxytyraMine hydrochloride >=99.0% (AT) 3-methoxytyramine Solution, 100ppm 3-Methoxytyramine hydrochloride, >=95% 3-METHOXY-4-HYDROXYPHENYLETHYLAMINE 4-HYDROXY-3-METHOXYPHENYLETHYLAMINE 2-Methoxytyramine hydrochloride 3-O-MethyldopaMine hydrochloride, 99+% 100MG 3-MT · HCl, 3-O-MethyldopaMine · HCl Phenol, 4-(2-aminoethyl)-2-methoxy-, hydrochloride (1:1) 3-Methoxytyramine hydrochloride ,99% 3-Methoxytyramine hydrochloride,3-MT, 3-Methoxy-4-hydroxyphenethylamine hydrochloride, 4-(2-Aminoethyl)-2-methoxyphenol hydrochloride 4-Hydroxy-3-methoxyphenethylamine hydrochlorideCONTROLLED DRUG CLASS A SCHEDULE 1 2-ethyl-d4-aMine HCl 3-O-Methyldopamine hydrochloridene hydrochloride 3-Methoxy-4-hydroxyphenethylamine hydrochloride, 3-MT, 4-(2-Aminoethyl)-2-methoxyphenol hydrochloride Dopamine Impurity 2(3-O-Methyldopamine Hydrochloride) 3-O-Methyldopamine hydrochloride Solution, 1000ppm Dopamine Impurity 2 3-Methoxytyramine hydrochloride salt Methoxytyramine in Methanol 3-O-Methyldopamine hydrochloride ISO 9001：2015 REACH 5-(2-Aminoethyl)guajakolhydrochlorid 3-Methoxy-p-tyramine D3 HydrochlorideQ: What is 3-Methoxy-p-tyramine D3 Hydrochloride Q: What is the CAS Number of 3-Methoxy-p-tyramine D3 Hydrochloride Q: What is the storage condition of 3-Methoxy-p-tyramine D3 Hydrochloride Q: What are the applications of 3-Methoxy-p-tyramine D3 Hydrochloride 3-O Methyl dopamine HydrochlorideQ: What is 3-O Methyl dopamine Hydrochloride Q: What is the CAS Number of 3-O Methyl dopamine Hydrochloride Q: What is the storage condition of 3-O Methyl dopamine Hydrochloride Q: What are the applications of 3-O Methyl dopamine Hydrochloride 3-O-Methyldopamine hydrochloride 1477-68-5 4-(2-AMINOETHYL)-2-METHOXYPHENOL HYDROCHLORIDE 3-METHOXYTYRAMINE HCL 3-METHOXYTYRAMINE HYDROCHLORIDE 3-METHOXYTYRAMINE 3-Methoxy-p-tyraMine Hydrochloride Phenol, 4-(2-aminoethyl)-2-methoxy-, HCl Dopamine Impurity 2(Dopamine EP Impurity B HCl) Reference material for methoxymethyl amine solution in methanol 3-Methoxy-p-tyramine Hydrochloride/3-O-Methyldopamine hydrochloride 3-Methoxy-p-tyramine Hydrochloride in Methanol(as free base) 3-Methoxytyramine hydrochloride, 10 mM in DMSO Dopamine Related Compound B 1477-68-5 1477-68-0 CH3OC6H34OHCH2CH2NH2HCl