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BERBERINE CHLORIDE

CAS No.
141433-60-5
Chemical Name:
BERBERINE CHLORIDE
Synonyms
BERBERINE HCL;BBR;BERBERIN HCL;5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE;Berberine chloride hydrate 97%;CI 75160;UMBELLATINE;BERBERINE CHLORIDE;TIMTEC-BB SBB006488;LABOTEST-BB LT00440956
CBNumber:
CB0758776
Molecular Formula:
C20H20ClNO5
Molecular Weight:
389.83
MDL Number:
MFCD00011939
MOL File:
141433-60-5.mol
Last updated:2025-02-21 21:32:25

BERBERINE CHLORIDE Properties

Melting point 204-206 °C (dec.)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
Colour Index 75160
color Pale Yellow to Yellow
Water Solubility Soluble in water.
Sensitive Light Sensitive
Merck 14,1154
BRN 3836585
Stability Hygroscopic
InChIKey VKJGBAJNNALVAV-UHFFFAOYSA-M
CAS DataBase Reference 141433-60-5(CAS DataBase Reference)
FDA UNII UOT4O1BYV8
NCI Drug Dictionary berberine chloride
UNSPSC Code 12352103
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn
Risk Statements  20/21/22
WGK Germany  2
RTECS  DR9866400
3-10
TSCA  Yes
HS Code  29399990
NFPA 704
1
0 0

BERBERINE CHLORIDE price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 14050 Berberine chloride hydrate technical, ≥90% (AT) 141433-60-5 10g $67.7 2024-03-01 Buy
Sigma-Aldrich 14050 Berberine chloride hydrate technical, ≥90% (AT) 141433-60-5 50g $82 2024-03-01 Buy
TCI Chemical B0450 Berberine Chloride Hydrate >98.0%(HPLC)(T) 141433-60-5 5g $33 2024-03-01 Buy
TCI Chemical B0450 Berberine Chloride Hydrate >98.0%(HPLC)(T) 141433-60-5 25g $77 2024-03-01 Buy
Alfa Aesar L03807 Berberine chloride hydrate, 97%, water <17% 141433-60-5 5g $28.65 2024-03-01 Buy
Product number Packaging Price Buy
14050 10g $67.7 Buy
14050 50g $82 Buy
B0450 5g $33 Buy
B0450 25g $77 Buy
L03807 5g $28.65 Buy

BERBERINE CHLORIDE Chemical Properties,Uses,Production

Description

Berberine chloride occurs together with Neprotine (q.v.) in Berberis insignis Hook, B. umbellata Wall and Mahonia nepalensis DC. (Syn. Berberis nepalensis Spreng.). It is optically inactive and crystallizes from H2O with 5.5 H2O. It yields crystal_x0002_line salts, e.g. the nitrate, m.p. 265-7°C (dec.); sulphate, m.p. 271-3°C (dec.) and the picrate, m.p. 231°C (dec.). The base also furnishes a methyl ether, m.p. 265°C and on catalytic hydrogenation gives the tetrahydro derivative, m.p. 213-5°C (dec.). The ultraviolet spectrum resembles that of berberine (q.v.). Oxidation with KMn04 in Me2CO gives hemipinic acid, identified as the ethylimide, m.p. 90°C.

Uses

Berberine chloride is mainly used to treat gastroenteritis, dysentery and other intestinal infections, conjunctivitis and suppurative otitis media.

General Description

Berberine chloride is an alkaloid with antibiotic properties. Berberine chloride induces reactive oxygen species (ROS) production and inhibits DNA topoisomerase. It has anti-tumor properties.

References

Orekhov.,J. Amer. Pharm. Assoc., 30,247, (1941)
Chatterjee., ibid, 33,205,210 (1944)

BERBERINE CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 313)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5868 58
Hebei Kingfiner Technology Development Co.Ltd
+86-15532196582 +86-15373005021 lisa@kingfinertech.com China 3005 58
Suzhou Yuanrui Bio-Tech Co., Ltd
+86-18106132862 +86-18106132862 sales02@yuanruibio.com China 285 58
Jinan Million Pharmaceutical Co., Ltd
0531-68659554 +8613031714605 info@millionpharm.com China 294 58
Hebei Zhuanglai Chemical Trading Co Ltd
+86-16264648883 +86-16264648883 niki@zlchemi.com China 7245 58
Shandong Xuhuang New material CoLTD
+86-15095020839 +86-17660422208 China 726 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21628 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682 bruce@xrdchem.cn CHINA 566 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479 sales@fine-chemtech.com CHINA 885 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29858 58

View Lastest Price from BERBERINE CHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Berberine HCl pictures 2025-04-25 Berberine HCl
141433-60-5
US $150.00 / kg 1kg 99% 500kg Hebei Zhuanglai Chemical Trading Co Ltd
BERBERINE CHLORIDE pictures 2025-04-25 BERBERINE CHLORIDE
141433-60-5
US $1.00 / ton 21ton 99.98 ton Jinan Million Pharmaceutical Co., Ltd
Berberine hydrochloride pictures 2025-03-21 Berberine hydrochloride
141433-60-5
US $50.00 / kg 1kg 99.99% 200 Shandong Xuhuang New material CoLTD
  • Berberine HCl pictures
  • Berberine HCl
    141433-60-5
  • US $150.00 / kg
  • 99%
  • Hebei Zhuanglai Chemical Trading Co Ltd
5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride hydrate Berberine chloride hydrate, 97%, water <17% Berberine (berberine hydrochloride) 9,10-DiMethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iuM chloride hydrate Berberine chloride hydrate technical, >=90% (AT) LABOTEST-BB LT00440956 CI 75160 BERBERINE HYDROCHLORIDE N-HYDRATE BERBERINE CHLORIDE 9,10-DIMETHOXY-5,6-DIHYDRO-[1,3]DIOXOLO[4,5-G]ISOQUINO[3,2-A]ISOQUINOLIN-7-YLIUM Berberine Hydrochloride、Berberine Sulphate UMBELLATINE NATURAL YELLOW 18 CHLORIDE TIMTEC-BB SBB006488 Berberine chloride std. Berberin hydrochloride Berberine chloride hydrate, 13.18 % water Berberine Chloride n-Hydrate Berberine Chloride Hydrate> BERBERINE CHLORIDE HYDRATE 141433-60-5 BERBERINE CHLORIDE USP/EP/BP 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride dihydrate Berberine chloride, hydrate (technical) ≥90% TIANFU-CHEM BERBERINE CHLORIDE Berberine Chloride HyBerberine Chloride Hydratedrate Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-, chloride, hydrate (1:1:) Berberine chloride hydrate 97% BERBERIN HCL BERBERINE HCL BBR 5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride, hydrate (1:1:x) 5,6-dihydro-9,10-dimethoxy-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride hydrate (1:1:) 5,6-Dihydro-9,10-dimethoxy-benzogbenzod1,3dioxolo5,6-aquinolizinium chloride hydrate (1:1:) Berberine chloride hydrate, 13.18 % water in DMSO 141433-60-5 C20H18NO4ClH2O C20H17NO4HCl BioChemical Antitumor Agents Anti-Proliferative Agents Cancer Research Isoquinoline Alkaloids Alkaloids Alkaloids Biochemistry Miscellaneous Natural Products Isoquinoline Alkaloids