Berberine Hcl
- CAS No.
- 141433-60-5
- Chemical Name:
- Berberine Hcl
- Synonyms
- BERBERINE HCL;BBR;BERBERIN HCL;5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE;Berberine chloride hydrate 97%;CI 75160;UMBELLATINE;BERBERINE CHLORIDE;TIMTEC-BB SBB006488;LABOTEST-BB LT00440956
- CBNumber:
- CB00126148
- Molecular Formula:
- C20H20ClNO5
- Molecular Weight:
- 389.83
- MDL Number:
- MFCD00011939
- MOL File:
- 141433-60-5.mol
| Melting point | 204-206 °C (dec.) |
|---|---|
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| Colour Index | 75160 |
| color | Pale Yellow to Yellow |
| Water Solubility | Soluble in water. |
| Sensitive | Light Sensitive |
| Merck | 14,1154 |
| BRN | 3836585 |
| Stability | Hygroscopic |
| InChIKey | VKJGBAJNNALVAV-UHFFFAOYSA-M |
| CAS DataBase Reference | 141433-60-5(CAS DataBase Reference) |
| FDA UNII | UOT4O1BYV8 |
| NCI Drug Dictionary | berberine chloride |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | DR9866400 | |||||||||
| F | 3-10 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29399990 | |||||||||
| NFPA 704 |
|
Berberine Hcl price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 14050 | Berberine chloride hydrate technical, ≥90% (AT) | 141433-60-5 | 10g | $67.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | 14050 | Berberine chloride hydrate technical, ≥90% (AT) | 141433-60-5 | 50g | $82 | 2024-03-01 | Buy |
| TCI Chemical | B0450 | Berberine Chloride Hydrate >98.0%(HPLC)(T) | 141433-60-5 | 5g | $33 | 2024-03-01 | Buy |
| TCI Chemical | B0450 | Berberine Chloride Hydrate >98.0%(HPLC)(T) | 141433-60-5 | 25g | $77 | 2024-03-01 | Buy |
| Alfa Aesar | L03807 | Berberine chloride hydrate, 97%, water <17% | 141433-60-5 | 5g | $28.65 | 2024-03-01 | Buy |
Berberine Hcl Chemical Properties,Uses,Production
benefits
Berberine Hcl, a quaternary ammonium salt of an isoquinoline alkaloid and active component of various Chinese herbs, with potential antineoplastic, radiosensitizing, anti-inflammatory, anti-lipidemic and antidiabetic activities.
Biological Activity
Although the mechanisms of action through which Berberine Hcl exerts its effects are not yet fully elucidated, upon administration this agent appears to suppress the activation of various proteins and/or modulate the expression of a variety of genes involved in tumorigenesis and inflammation, including, but not limited to transcription factor nuclear factor-kappa B (NF-kB), myeloid cell leukemia 1 (Mcl-1), B-cell lymphoma 2 (Bcl-2), B-cell lymphoma-extra large (Bcl-xl), cyclooxygenase (COX)-2, tumor necrosis factor (TNF), interleukin (IL)-6, IL-12, inducible nitric oxide synthase (iNOS), intercellular adhesion molecule-1 (ICAM-1), E-selectin, monocyte chemoattractant protein-1 (MCP-1), C-X-C motif chemokine 2 (CXCL2), cyclin D1, activator protein (AP-1), hypoxia-inducible factor 1 (HIF-1), signal transducer and activator of transcription 3 (STAT3), peroxisome proliferator-activated receptor (PPAR), arylamine N-acetyltransferase (NAT), and DNA topoisomerase I and II. The modulation of gene expression may induce cell cycle arrest and apoptosis, and inhibit cancer cell proliferation.
Plant extract
Berberine and Berberine Hcl are not the same. Berberine is a yellow-colored alkaloid found in certain plants. However, Berberine Hcl is crude berberine which has been chemically altered to become an alkaloidal salt. It may help to treat diabetes, high cholesterol, and high blood pressure, among other conditions. However, side effects can include upset stomach and nausea. Berberine has been a part of Chinese and Ayurvedic medicine for thousands of years.
Berberine Hcl Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Duling International Trade Co. LTD | +8617333973358 | sales01@hbduling.cn | China | 15458 | 58 |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 2990 | 58 |
| Suzhou Yuanrui Bio-Tech Co., Ltd | +86-18106132862 +86-18106132862 | sales02@yuanruibio.com | China | 281 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21681 | 55 |
| Hubei XinRunde Chemical Co., Ltd. | +8615102730682 | bruce@xrdchem.cn | CHINA | 566 | 55 |
| Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
| career henan chemical co | +86-0371-86658258 15093356674; | sales@coreychem.com | China | 29914 | 58 |
| Shaanxi Yikanglong Biotechnology Co., Ltd. | 17791478691 | yklbiotech@163.com | CHINA | 296 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2141 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
View Lastest Price from Berberine Hcl manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-08-21 | Sodium tetraborate pentahydrate
12179-04-3
|
1kg | 99% | 100tons | Anhui Ruihan Technology Co., Ltd |
-
- Sodium tetraborate pentahydrate
12179-04-3
- 99%
- Anhui Ruihan Technology Co., Ltd
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