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Amino-PEG24-acid

Amino-PEG24-acid structure

CAS No.: 2563873-76-5

Chemical Name:: Amino-PEG24-acid

Synonyms: Amino-PEG24-propionic acid;1-Amino-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72-tetracosaoxapentaheptacontan-75-oic acid;H2N-PEG24-CH2CH2COOH/ Propanoic acid, 3-[(71-amino-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69-tricosaoxahenheptacont-1-yl)oxy]-

CBNumber:: CB99405317

Molecular Formula:: C51H103NO26

Molecular Weight:: 1146.37

MDL Number:

MOL File:: 2563873-76-5.mol

Last updated:2024-07-02 08:55:42

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Amino-PEG24-acid Properties

Boiling point	952.9±65.0 °C(Predicted)
Density	1.122±0.06 g/cm3(Predicted)
form	Solid
pka	4.28±0.10(Predicted)
color	White to off-white

Amino-PEG24-acid Chemical Properties,Uses,Production

Biological Activity

Amino-PEG24-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Amino-PEG24-acid Preparation Products And Raw materials

Raw materials

Preparation Products

Amino-PEG24-acid Suppliers

Global( 16)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Alpha Biopharmaceuticals Co., Ltd	+86-15542445688	sales@alabiochem.com	China	888	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42057	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Alabiochem Tech.Co., Ltd.	0512-58900862 400-0707518	sales@alabiochem.com	China	997	59
Bide Pharmatech Ltd.	400-164-7117 13681763483	product02@bidepharm.com	China	41463	60
Amatek Scientific Co. Ltd.	0512-56316828	info@amateksci.com	China	28817	58
Shanghai Haohong Pharmaceutical Co., Ltd.	4008210725 4008210725	malulu@leyan.com	China	54986	58
Guangzhou Hongyuan Chemical Co.,Ltd	15817493340	981810490@qq.com	China	1565	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 15801484223;	psaitong@jm-bio.com	China	29778	58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd	0431-80514535 19917294565	et@chemextension.com	China	5061	58

Supplier	Advantage
Alpha Biopharmaceuticals Co., Ltd	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Aladdin Scientific	58
Alabiochem Tech.Co., Ltd.	59
Bide Pharmatech Ltd.	60
Amatek Scientific Co. Ltd.	58
Shanghai Haohong Pharmaceutical Co., Ltd.	58
Guangzhou Hongyuan Chemical Co.,Ltd	58
Beijing Jin Ming Biotechnology Co., Ltd.	58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd	58

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H2N-PEG24-CH2CH2COOH/ Propanoic acid, 3-[(71-amino-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69-tricosaoxahenheptacont-1-yl)oxy]- Amino-PEG24-propionic acid 1-Amino-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72-tetracosaoxapentaheptacontan-75-oic acid 2563873-76-5 QTJ