| Company Name: |
Alabiochem Tech.Co., Ltd.
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| Tel: |
0512-58900862 400-0707518 |
| Email: |
sales@alabiochem.com |
| Products Intro: |
Product Name:Amino-PEG24-Acid;H2N-PEG24-CH2CH2COOH
CAS:2563873-76-5
Purity:98% Package:1g;5g;25; 100g;bulk
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| Company Name: |
Amatek Scientific Co. Ltd.
|
| Tel: |
0512-56316828 |
| Email: |
info@amateksci.com |
| Products Intro: |
Product Name:H2N-PEG24-CH2CH2COOH
CAS:2563873-76-5
Purity:97% HPLC Package:1g;5g;25g;100g
|
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| | Amino-PEG24-acid Basic information |
| Product Name: | Amino-PEG24-acid | | Synonyms: | H2N-PEG24-CH2CH2COOH/
Propanoic acid, 3-[(71-amino-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69-tricosaoxahenheptacont-1-yl)oxy]- | | CAS: | 2563873-76-5 | | MF: | C51H103NO26 | | MW: | 1146.37 | | EINECS: | | | Product Categories: | QTJ | | Mol File: | 2563873-76-5.mol |  |
| | Amino-PEG24-acid Chemical Properties |
| Boiling point | 952.9±65.0 °C(Predicted) | | density | 1.122±0.06 g/cm3(Predicted) | | form | Solid | | pka | 4.28±0.10(Predicted) | | color | White to off-white |
| | Amino-PEG24-acid Usage And Synthesis |
| Biological Activity | Amino-PEG24-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Amino-PEG24-acid Preparation Products And Raw materials |
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