ChemicalBook >> CAS DataBase List >>2-Amino-3-o-chlorobenzoyl-5-ethylthiophene

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene

CAS No.
50508-60-6
Chemical Name:
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene
Synonyms
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene;2-Amino-5-ethyl-3-(2-chlorobenzoyl)thiophene;Methanone,(2-aMino-5-ethyl-3-thienyl)(2-chlorophenyl)-;(2-AMino-5-ethylthiophen-3-yl)(2-chlorophenyl)Methanone
CBNumber:
CB9947146
Molecular Formula:
C13H12ClNOS
Molecular Weight:
265.76
MDL Number:
MFCD04107940
MOL File:
50508-60-6.mol
MSDS File:
SDS
Last updated:2023-06-08 09:03:05

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Properties

Boiling point 454.8±45.0 °C(Predicted)
Density 1.302
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): insol
form a crystalline solid
pka -1.81±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
NFPA 704
0
2 0

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A603355 2-Amino-3-(2-chlorobenzoyl)-5-ethylthiophene 50508-60-6 100mg $60 2021-12-16 Buy
American Custom Chemicals Corporation HCH0011027 2-AMINO-3-O-CHLOROBENZOYL-5-ETHYLTHIOPHENE 95.00% 50508-60-6 5MG $500.2 2021-12-16 Buy
AK Scientific Z5530 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene 50508-60-6 1g $120 2021-12-16 Buy
Matrix Scientific 093974 (2-Amino-5-ethylthiophen-3-yl)-(2-chlorophenyl)methanone 95+% 50508-60-6 250mg $756 2021-12-16 Buy
Matrix Scientific 093974 (2-Amino-5-ethylthiophen-3-yl)-(2-chlorophenyl)methanone 95+% 50508-60-6 1g $1647 2021-12-16 Buy
Product number Packaging Price Buy
A603355 100mg $60 Buy
HCH0011027 5MG $500.2 Buy
Z5530 1g $120 Buy
093974 250mg $756 Buy
093974 1g $1647 Buy

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Chemical Properties,Uses,Production

Description

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene can be used as the raw material for the synthesis of Etizolam, which is an important sedative hypnotic and antidepressant drug. Its derivative, 2-amino-3-(p-chlorobenzoyl) thiophene scaffold has been widely employed as a pharmacophore for the identification of small molecules acting as allosteric modulators at the adenosine A1 receptor. 

References

Kai, Yong Mao, et al. "An Improved Synthesis of Etizolam." Journal of Southwest University of Science & Technology  (2014).
Romagnoli, R, et al. Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study..Longing for the end. Macmillan, 2015:185–204.

Chemical Properties

Yellow Solid

Uses

Used in the preparation of thienylamide derivatives as cholecystokinin inhibitors.

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 93)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Hangzhou FandaChem Co.,Ltd.
+8615858145714 FandaChem@Gmail.com China 9215 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32951 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29885 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569266 15319487004 1015@dideu.com China 4087 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34553 58

View Lastest Price from 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene pictures 2019-07-06 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene
50508-60-6
US $1.00 / kg 1kg 98% 100KG Career Henan Chemical Co
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene 2-Amino-5-ethyl-3-(2-chlorobenzoyl)thiophene Methanone,(2-aMino-5-ethyl-3-thienyl)(2-chlorophenyl)- (2-AMino-5-ethylthiophen-3-yl)(2-chlorophenyl)Methanone 50508-60-6 Thiophene heterocycles