2-Amino-3-o-chlorobenzoyl-5-ethylthiophene
- CAS No.
- 50508-60-6
- Chemical Name:
- 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene
- Synonyms
- 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene;2-Amino-5-ethyl-3-(2-chlorobenzoyl)thiophene;Methanone,(2-aMino-5-ethyl-3-thienyl)(2-chlorophenyl)-;(2-AMino-5-ethylthiophen-3-yl)(2-chlorophenyl)Methanone
- CBNumber:
- CB9947146
- Molecular Formula:
- C13H12ClNOS
- Molecular Weight:
- 265.76
- MDL Number:
- MFCD04107940
- MOL File:
- 50508-60-6.mol
- MSDS File:
- SDS
Boiling point | 454.8±45.0 °C(Predicted) |
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Density | 1.302 |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): insol |
form | a crystalline solid |
pka | -1.81±0.10(Predicted) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
NFPA 704 |
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2-Amino-3-o-chlorobenzoyl-5-ethylthiophene price More Price(26)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | A603355 | 2-Amino-3-(2-chlorobenzoyl)-5-ethylthiophene | 50508-60-6 | 100mg | $60 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | HCH0011027 | 2-AMINO-3-O-CHLOROBENZOYL-5-ETHYLTHIOPHENE 95.00% | 50508-60-6 | 5MG | $500.2 | 2021-12-16 | Buy |
AK Scientific | Z5530 | 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene | 50508-60-6 | 1g | $120 | 2021-12-16 | Buy |
Matrix Scientific | 093974 | (2-Amino-5-ethylthiophen-3-yl)-(2-chlorophenyl)methanone 95+% | 50508-60-6 | 250mg | $756 | 2021-12-16 | Buy |
Matrix Scientific | 093974 | (2-Amino-5-ethylthiophen-3-yl)-(2-chlorophenyl)methanone 95+% | 50508-60-6 | 1g | $1647 | 2021-12-16 | Buy |
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Chemical Properties,Uses,Production
Description
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene can be used as the raw material for the synthesis of Etizolam, which is an important sedative hypnotic and antidepressant drug. Its derivative, 2-amino-3-(p-chlorobenzoyl) thiophene scaffold has been widely employed as a pharmacophore for the identification of small molecules acting as allosteric modulators at the adenosine A1 receptor.
References
Kai, Yong Mao, et al. "An Improved Synthesis of Etizolam." Journal of Southwest University of Science & Technology (2014).
Romagnoli, R, et al. Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study..Longing for the end. Macmillan, 2015:185–204.
Chemical Properties
Yellow Solid
Uses
Used in the preparation of thienylamide derivatives as cholecystokinin inhibitors.
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9215 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32951 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29885 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | 1015@dideu.com | China | 4087 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34553 | 58 |
View Lastest Price from 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2019-07-06 | 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene
50508-60-6
|
US $1.00 / kg | 1kg | 98% | 100KG | Career Henan Chemical Co |
- 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene
50508-60-6
- US $1.00 / kg
- 98%
- Career Henan Chemical Co