7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL

7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL Structure
CAS No.
6272-55-5
Chemical Name:
7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL
Synonyms
7,8,9,10-tetrahydro-benzo(a)pyren-7-o;Benzo[a]pyren-7-ol, 7,8,9,10-tetrahydro-;7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-7-OL;7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol;7,8,9,10-TETRAHYDROBENZO(A)PYREN-7-OL, 9 9%;7-Hydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene
CBNumber:
CB0145107
Molecular Formula:
C20H16O
Molecular Weight:
272.34
MOL File:
6272-55-5.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:54:57

7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL Properties

Melting point 142-144 °C(lit.)
Boiling point 508.5±19.0 °C(Predicted)
Density 1.323±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.2 mg/ml
form A crystalline solid
pka 14.36±0.20(Predicted)
color Light brown to brown

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
WGK Germany  3
RTECS  DJ8304000

7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 391611 7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol 98% 6272-55-5 5G ₹23490.25 2022-06-14 Buy
Product number Packaging Price Buy
391611 5G ₹23490.25 Buy

7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL Chemical Properties,Uses,Production

Description

7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is a benzopyrene derivative that is activated by hepatic cytosol into electrophilic sulfuric acid esters, which are capable of forming covalent DNA adducts and inducing mutations.

Chemical Properties

Yellow Solid

Uses

7,8,9,10-Tetrahydro-benzo[a]pyren-7-ol is a Benzopyrene (B205800) derivative, activated by hepatic cytosol.

General Description

7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol (7-hydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene), a polycyclic aromatic hydrocarbon (PAH), is a substituted benzopyrene. Its bromination reaction with N-bromosaccharin (NBSac) has been investigated. The sulfotransferase-assisted activation of 7-hydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene to form electrophilic, mutagenic, or tumorigenic sulfuric acid ester metabolite, which binds covalently to DNA and leads to mutation, has been reported.

7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL Preparation Products And Raw materials

Raw materials

Preparation Products

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7,8,9,10-TETRAHYDRO-BENZO[A]PYREN-7-OL Spectrum

7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-7-OL 7,8,9,10-tetrahydro-benzo(a)pyren-7-o 7-Hydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene 7,8,9,10-TETRAHYDROBENZO(A)PYREN-7-OL, 9 9% Benzo[a]pyren-7-ol, 7,8,9,10-tetrahydro- 7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol 6272-55-5 C20H16O Oxygen Compounds Organic Building Blocks Alcohols Building Blocks C9 to C30 Alcohols C9 to C30 Oxygen Compounds Building Blocks C11 to C30+ Chemical Synthesis Organic Building Blocks Oxygen Compounds