ChemicalBook > Product Catalog >Organic Chemistry >Amides >Amino compound >[2-(aminomethyl)phenyl]methanol

[2-(aminomethyl)phenyl]methanol

[2-(aminomethyl)phenyl]methanol Structure
CAS No.
4152-92-5
Chemical Name:
[2-(aminomethyl)phenyl]methanol
Synonyms
RARECHEM GT HW 0287;UKRORGSYN-BB BBV-182531;o-(Hydroxymethyl)benzylamine;[2-(aminomethyl)phenyl]methanol
CBNumber:
CB01594964
Molecular Formula:
C8H11NO
Molecular Weight:
137.18
MOL File:
4152-92-5.mol
MSDS File:
SDS
Modify Date:
2022/12/21 16:56:50

[2-(aminomethyl)phenyl]methanol Properties

Boiling point 271℃
Density 1.113
Flash point 118℃
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 14.28±0.10(Predicted)

[2-(aminomethyl)phenyl]methanol Chemical Properties,Uses,Production

Uses

[2-(aminomethyl)phenyl]methanol can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

(4-Aminomethyl-phenyl)-methanol hydrochloride salt 4-Hydroxymethyl-benzonitrile (2.0 g, 15 mol) was reduced using Raney nickel (0. 5g) and hydrogen (50 psi) in MeOH: NH3 (100ml) for 20 hours. The reaction mixture was filtered through a pad of celite. The filtrate was concentrated under reduced pressure to afford (4-aminomethyl-phenyl)-methanol hydrochloride salt (2.01 g, 98percent) as a white solid of sufficient purity for use without further purification: MS (APCI+) : m/z 138.3 (M+H).

[2-(aminomethyl)phenyl]methanol Preparation Products And Raw materials

Raw materials

Preparation Products

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[2-(aminomethyl)phenyl]methanol RARECHEM GT HW 0287 UKRORGSYN-BB BBV-182531 o-(Hydroxymethyl)benzylamine 4152-92-5