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TCS 46B

TCS 46B Structure
CAS No.
302799-86-6
Chemical Name:
TCS 46B
Synonyms
TCS 46B;1,3-Dihydro-5-[3-[4-(phenylmethyl)-1-2H-benzimidazol-2-one;2H-Benzimidazol-2-one, 1,3-dihydro-5-[3-[4-(phenylmethyl)-1-piperidinyl]-1-propyn-1-yl]-
CBNumber:
CB02453446
Molecular Formula:
C22H23N3O
Molecular Weight:
345.44
MOL File:
302799-86-6.mol
Modify Date:
2024/7/2 8:54:57
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TCS 46B Properties

Boiling point 440.4±38.0 °C(Predicted)
Density 1.24±0.1 g/cm3(Predicted)
storage temp. Store at RT
solubility Soluble to 100 mM in DMSO and to 100 mM in ethanol
form Powder
pka 11.51±0.30(Predicted)
color Off-white to light yellow

TCS 46B Chemical Properties,Uses,Production

Uses

TCS 46b is a subtype-selective NR1A/NR2B NMDA receptor antagonist.

Biological Activity

Orally active, subtype-selective NR1A/NR2B NMDA receptor antagonist (IC 50 values are 5.3, 35000 and > 100000 nM for NR1A/2B, NR1A/2A and NR1A/2C receptor subtypes respectively). Potentiates the effect of L-DOPA in 6-OHDA-lesioned rats following oral administration.

TCS 46B Preparation Products And Raw materials

Raw materials

Preparation Products

TCS 46B Suppliers

Global( 31)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Chemtour Biotech Co., Ltd +8617327281506 China 1460 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Anqing Rong Chuang Biological Technology Co., Ltd. 15001988657 China 955 58 Inquiry
DC Chemicals 021-58447131 13564518121 China 9412 58 Inquiry
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 China 9929 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23963 58 Inquiry
BOC Sciences USA 0 65 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48467 58 Inquiry
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 60
TargetMol Chemicals Inc. 58
Chemtour Biotech Co., Ltd 58
Aladdin Scientific 58
Anqing Rong Chuang Biological Technology Co., Ltd. 58
DC Chemicals 58
Shanghai Chaolan Chemical Technology Center 58
TargetMol Chemicals Inc. 58
BOC Sciences 65
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58

TCS 46B Spectrum

TCS 46B(302799-86-6)1HNMR

302799-86-6(TCS 46B)Related Search:

N-BUTYL-3-PHENYLPROP-2-YN-1-AMINE TCS 46B
TCS 46B 1,3-Dihydro-5-[3-[4-(phenylmethyl)-1-2H-benzimidazol-2-one 2H-Benzimidazol-2-one, 1,3-dihydro-5-[3-[4-(phenylmethyl)-1-piperidinyl]-1-propyn-1-yl]- 302799-86-6