DDHL
- CAS No.
- 137173-46-7
- Chemical Name:
- DDHL
- Synonyms
- DDHL;C12-HSL;abs47045015;C12-HOMOSERINE LACTONE;N-Lauroyl-L-homoserine lactone;Dodecanoyl-L-hoMoserine lactone;N-DODECANOYL-L-HOMOSERINE LACTONE;N-[(3S)-2-oxooxolan-3-yl]dodecanamide;(S)-N-(2-Oxotetrahydrofuran-3-yl)dodecanamide;N-[(3S)-Tetrahydro-2-oxo-3-furanyl]dodecanamide
- CBNumber:
- CB02468631
- Molecular Formula:
- C16H29NO3
- Molecular Weight:
- 283.41
- MOL File:
- 137173-46-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:54:57
| Melting point | 128 °C(Solv: ethyl acetate (141-78-6)) |
|---|---|
| Boiling point | 485.8±34.0 °C(Predicted) |
| Density | 1.00±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Chloroform: 10 mg/ml; DMF: 1 mg/ml; DMSO: 1 mg/ml |
| form | A crystalline solid |
| pka | 14.71±0.20(Predicted) |
| color | White to off-white |
| optical activity | [α]/D -25±5°, c = 0.2 in methanol |
| BRN | 9281984 |
DDHL price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 68224 | N-Dodecanoyl-L-homoserine lactone ≥96% (HPLC) | 137173-46-7 | 10MG | ₹16659.68 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 68224 | N-Dodecanoyl-L-homoserine lactone ≥96% (HPLC) | 137173-46-7 | 50MG | ₹50715.13 | 2022-06-14 | Buy |
DDHL Chemical Properties,Uses,Production
Uses
Dodecanoyl-L-homoserine lactone was confirmed to be an active quorum sensing modulator first recognised in Sinorhizobium meliloti. N-Acylhomoserine lactones have been detected in hundreds of bacterial species and, while the homologues vary between species and strains, the homoserine lactones are the major chemical modulators of within and between cell communication and regulation. The most significant variable defining the function of the homoserine lactone is the length of the acyl chain, with shorter chains displaying opposing actions to the longer chains.
Definition
ChEBI: An N-acyl-L-homoserine lactone having dodecanoyl as the acyl substituent.
Biochem/physiol Actions
N-Dodecanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria; for reviews see. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs, and a research focus for the prevention of biofilm formation.
DDHL Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | China | 48465 | 58 | Inquiry |
| Nantong Hanfang Biotechnology Co. , Ltd. | 18616537568 | China | 30968 | 58 | Inquiry |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 18521078705 | China | 19928 | 58 | Inquiry |
| InvivoChem | 13549236410 | China | 6755 | 58 | Inquiry |
| SHANGHAI ZZBIO CO., LTD. | 15102117276 19921389125 | China | 12064 | 58 | Inquiry |
| Wuhan Topule | +86-02787215551 +86-19945035818 | China | 8206 | 58 | Inquiry |