L(+)-Arginine
![L(+)-Arginine Structure](CAS/GIF/74-79-3.gif)
- CAS No.
- 74-79-3
- Chemical Name:
- L(+)-Arginine
- Synonyms
- L-ARGININE;ARG;L-ARGININE BASE;H-ARG-OH;L-ARG;L-Arginine acid;l-arginin;Carmosine;L-Argenine;(S)-2-AMINO-5-GUANIDINOPENTANOIC ACID
- CBNumber:
- CB9226645
- Molecular Formula:
- C6H14N4O2
- Molecular Weight:
- 174.2
- MOL File:
- 74-79-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/10 17:45:06
Melting point | 222 °C (dec.) (lit.) |
---|---|
alpha | 27.1 º (c=8, 6N HCl) |
Boiling point | 305.18°C (rough estimate) |
Density | 1.2297 (rough estimate) |
FEMA | 3819 | L-ARGININE |
refractive index | 27 ° (C=8, 6mol/L HCl) |
storage temp. | 2-8°C |
solubility | H2O: 100 mg/mL |
form | powder |
pka | 1.82, 8.99, 12.5(at 25℃) |
color | white |
PH | 10.5-12.0 (25℃, 0.5M in H2O) |
PH Range | 10.5 - 12 |
Odor | Faint |
Odor Type | bland |
optical activity | [α]20/D +27°, c = 8 in 6 M HCl |
Water Solubility | 148.7 g/L (20 ºC) |
Sensitive | Air Sensitive |
λmax |
λ: 260 nm Amax: ≤0.2 λ: 280 nm Amax: ≤0.1 |
JECFA Number | 1438 |
Merck | 14,780 |
BRN | 1725413 |
Stability | Stable. Incompatible with strong oxidizing agents. |
InChIKey | ODKSFYDXXFIFQN-BYPYZUCNSA-N |
LogP | -4.20 |
CAS DataBase Reference | 74-79-3(CAS DataBase Reference) |
NIST Chemistry Reference | L-Arginine(74-79-3) |
EPA Substance Registry System | L-Arginine (74-79-3) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H319 | |||||||||
Precautionary statements | P264b-P280i-P305+P351+P338-P337+P313-P403-P501c | |||||||||
Hazard Codes | Xn,T | |||||||||
Risk Statements | 36-36/37/38-20/21/22-61 | |||||||||
Safety Statements | 24/25-36-26-45-53-39 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | CF1934200 | |||||||||
F | 10-23 | |||||||||
TSCA | Yes | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29252000 | |||||||||
Toxicity | cyt-grh-par 100 mmol/L IJEBA6 24,460,86 | |||||||||
NFPA 704 |
|
L(+)-Arginine price More Price(46)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | W381920 | L-Arginine natural, FCC, FG | 74-79-3 | 1SAMPLE-K | ₹5196 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | W381920 | L-Arginine natural, FCC, FG | 74-79-3 | 1KG | ₹10922.43 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | W381920 | L-Arginine natural, FCC, FG | 74-79-3 | 5KG | ₹37855.03 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | W381920 | L-Arginine natural, FCC, FG | 74-79-3 | 10KG | ₹66043.33 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | W381918 | L-Arginine 99%, FCC, FG | 74-79-3 | 1SAMPLE | ₹5141.88 | 2022-06-14 | Buy |
L(+)-Arginine Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder
Physical properties
Solubility 14.87 (20 ℃) g/100 g H2O, pI 10.76, dissociation constants: pK1 2.01, pK2 9.04 (a-NH2), pK3 12.48 (guanidyl).
Occurrence
Reported present in cheese, chocolate, eggs, meat, nuts and other products.
Uses
Amino acid; nutrient.
Definition
ChEBI: An L-alpha-amino acid that is the L-isomer of arginine.
General Description
L-Arginine is an amino acid that plays a key role in many physiological processes such as tissue repair and reproduction. It is a key precursor for synthesizing nitric oxide in mammals. Due to these factors, the dietary supplementation with L-arginine may show a range of health benefits.
Side effects
Nausea, abdominal pain and diarrhea
Bloating
Gout
Headache
Allergic response
Airway inflammation or worsening of asthma symptoms
Safety Profile
Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.
Drug interactions
L-arginine may interact with certain medications, including :
Blood-pressure-lowering medications: enalapril (Vasotec), losartan (Cozaar), amlodipine (Norvasc), furosemide (Lasix), etc.
Erectile dysfunction medications: sildenafil citrate (Viagra), tadalafil (Cialis), etc.
Blood-thinning medications: clopidogrel (Plavix), enoxaparin (Lovenox), heparin, warfarin (Coumadin), etc.
Antidiabetic medications: insulin, pioglitazone (Actos), glipizide (Glucotrol), etc.
Medications that increase blood flow: nitroglycerin (Nitro-Dur, Nitro-Bid, Nitrostat), isosorbide ( Sorbitrate, Imdur, Isordil), etc.
Diuretic medications: amiloride (Midamor), and triamterene (Dyrenium), spironolactone (Aldactone), etc.
Purification Methods
S-Arginine crystallises from H2O as the dihydrate and as plates from EtOH. It also crystallises from 66% EtOH. Its solubility in H2O is 15% at 21o. Its isoelectric point is at pH 10.76. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1841 1961, Beilstein 4 IV 817.]
L(+)-Arginine Preparation Products And Raw materials
Raw materials
Preparation Products
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Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 32 | 58 | Inquiry |
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AMINO ORGANICS | +919866989891 | Hyderabad, India | 275 | 58 | Inquiry |
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Dodhia Group | +91-9619867345 +91-9619867345 | Mumbai, India | 129 | 58 | Inquiry |
HRV Global Life Sciences | +91-9820219686 +91-9820219686 | Telangana, India | 379 | 58 | Inquiry |
Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
Innovative Health Care (India) Pvt. Ltd. | +91-4426289003 +91-6383884846 | Tamil Nadu, India | 14 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
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