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L(+)-Arginine

L(+)-Arginine Structure
CAS No.
74-79-3
Chemical Name:
L(+)-Arginine
Synonyms
L-ARGININE;ARG;L-ARGININE BASE;H-ARG-OH;L-ARG;L-Arginine acid;l-arginin;Carmosine;L-Argenine;(S)-2-AMINO-5-GUANIDINOPENTANOIC ACID
CBNumber:
CB9226645
Molecular Formula:
C6H14N4O2
Molecular Weight:
174.2
MOL File:
74-79-3.mol
MSDS File:
SDS
Modify Date:
2024/7/10 17:45:06

L(+)-Arginine Properties

Melting point 222 °C (dec.) (lit.)
alpha 27.1 º (c=8, 6N HCl)
Boiling point 305.18°C (rough estimate)
Density 1.2297 (rough estimate)
FEMA 3819 | L-ARGININE
refractive index 27 ° (C=8, 6mol/L HCl)
storage temp. 2-8°C
solubility H2O: 100 mg/mL
form powder
pka 1.82, 8.99, 12.5(at 25℃)
color white
PH 10.5-12.0 (25℃, 0.5M in H2O)
PH Range 10.5 - 12
Odor Faint
Odor Type bland
optical activity [α]20/D +27°, c = 8 in 6 M HCl
Water Solubility 148.7 g/L (20 ºC)
Sensitive Air Sensitive
λmax λ: 260 nm Amax: ≤0.2
λ: 280 nm Amax: ≤0.1
JECFA Number 1438
Merck 14,780
BRN 1725413
Stability Stable. Incompatible with strong oxidizing agents.
InChIKey ODKSFYDXXFIFQN-BYPYZUCNSA-N
LogP -4.20
CAS DataBase Reference 74-79-3(CAS DataBase Reference)
NIST Chemistry Reference L-Arginine(74-79-3)
EPA Substance Registry System L-Arginine (74-79-3)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264b-P280i-P305+P351+P338-P337+P313-P403-P501c
Hazard Codes  Xn,T
Risk Statements  36-36/37/38-20/21/22-61
Safety Statements  24/25-36-26-45-53-39
WGK Germany  3
RTECS  CF1934200
10-23
TSCA  Yes
HazardClass  IRRITANT
HS Code  29252000
Toxicity cyt-grh-par 100 mmol/L IJEBA6 24,460,86
NFPA 704
0
1 0

L(+)-Arginine price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) W381920 L-Arginine natural, FCC, FG 74-79-3 1SAMPLE-K ₹5196 2022-06-14 Buy
Sigma-Aldrich(India) W381920 L-Arginine natural, FCC, FG 74-79-3 1KG ₹10922.43 2022-06-14 Buy
Sigma-Aldrich(India) W381920 L-Arginine natural, FCC, FG 74-79-3 5KG ₹37855.03 2022-06-14 Buy
Sigma-Aldrich(India) W381920 L-Arginine natural, FCC, FG 74-79-3 10KG ₹66043.33 2022-06-14 Buy
Sigma-Aldrich(India) W381918 L-Arginine 99%, FCC, FG 74-79-3 1SAMPLE ₹5141.88 2022-06-14 Buy
Product number Packaging Price Buy
W381920 1SAMPLE-K ₹5196 Buy
W381920 1KG ₹10922.43 Buy
W381920 5KG ₹37855.03 Buy
W381920 10KG ₹66043.33 Buy
W381918 1SAMPLE ₹5141.88 Buy

L(+)-Arginine Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder

Physical properties

Solubility 14.87 (20 ℃) g/100 g H2O, pI 10.76, dissociation constants: pK1 2.01, pK2 9.04 (a-NH2), pK3 12.48 (guanidyl).

Occurrence

Reported present in cheese, chocolate, eggs, meat, nuts and other products.

Uses

Amino acid; nutrient.

Definition

ChEBI: An L-alpha-amino acid that is the L-isomer of arginine.

General Description

L-Arginine is an amino acid that plays a key role in many physiological processes such as tissue repair and reproduction. It is a key precursor for synthesizing nitric oxide in mammals. Due to these factors, the dietary supplementation with L-arginine may show a range of health benefits.

Side effects

Nausea, abdominal pain and diarrhea
Bloating
Gout
Headache
Allergic response
Airway inflammation or worsening of asthma symptoms

Safety Profile

Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.

Drug interactions

L-arginine may interact with certain medications, including :
Blood-pressure-lowering medications: enalapril (Vasotec), losartan (Cozaar), amlodipine (Norvasc), furosemide (Lasix), etc.
Erectile dysfunction medications: sildenafil citrate (Viagra), tadalafil (Cialis), etc.
Blood-thinning medications: clopidogrel (Plavix), enoxaparin (Lovenox), heparin, warfarin (Coumadin), etc.
Antidiabetic medications: insulin, pioglitazone (Actos), glipizide (Glucotrol), etc.
Medications that increase blood flow: nitroglycerin (Nitro-Dur, Nitro-Bid, Nitrostat), isosorbide ( Sorbitrate, Imdur, Isordil), etc.
Diuretic medications: amiloride (Midamor), and triamterene (Dyrenium), spironolactone (Aldactone), etc.

Purification Methods

S-Arginine crystallises from H2O as the dihydrate and as plates from EtOH. It also crystallises from 66% EtOH. Its solubility in H2O is 15% at 21o. Its isoelectric point is at pH 10.76. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1841 1961, Beilstein 4 IV 817.]

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