L-Malic acid
![L-Malic acid Structure](CAS/GIF/97-67-6.gif)
- CAS No.
- 97-67-6
- Chemical Name:
- L-Malic acid
- Synonyms
- L-MALIC ACID;L-Malic;(2S)-2-hydroxybutanedioic acid;L-Mailcacid;HYDROXYBUTANEDIOIC ACID;L-Gydroxybutanedioicacid;apple acid;pinguosuan;(S)-(-)-MALIC ACID;-(-)-MaL
- CBNumber:
- CB0493594
- Molecular Formula:
- C4H6O5
- Molecular Weight:
- 134.09
- MOL File:
- 97-67-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/19 17:35:41
Melting point | 101-103 °C (lit.) |
---|---|
Boiling point | 167.16°C (rough estimate) |
alpha | -2 º (c=8.5, H2O) |
Density | 1.60 |
vapor pressure | 0Pa at 25℃ |
FEMA | 2655 | L-MALIC ACID |
refractive index | -6.5 ° (C=10, Acetone) |
Flash point | 220 °C |
storage temp. | Store below +30°C. |
solubility | H2O: 0.5 M at 20 °C, clear, colorless |
form | Powder |
Specific Gravity | 1.595 (20/4℃) |
color | White |
PH | 2.2 (10g/l, H2O, 20℃) |
pka | (1) 3.46, (2) 5.10(at 25℃) |
Odor | odorless |
Odor Type | odorless |
optical activity | [α]20/D 30±2°, c = 5.5% in pyridine |
Water Solubility | soluble |
JECFA Number | 619 |
Merck | 14,5707 |
BRN | 1723541 |
InChIKey | BJEPYKJPYRNKOW-REOHCLBHSA-N |
LogP | -1.68 |
CAS DataBase Reference | 97-67-6(CAS DataBase Reference) |
NIST Chemistry Reference | Butanedioic acid, hydroxy-, (s)-(97-67-6) |
EPA Substance Registry System | Butanedioic acid, 2-hydroxy-, (2S)- (97-67-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H319 | |||||||||
Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-37/39 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | ON7175000 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29181980 | |||||||||
NFPA 704 |
|
L-Malic acid price More Price(21)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | M7397 | L-(−)-Malic acid suitable for cell culture, BioReagent, suitable for insect cell culture | 97-67-6 | 25G | ₹6419.23 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M7397 | L-(−)-Malic acid suitable for cell culture, BioReagent, suitable for insect cell culture | 97-67-6 | 100G | ₹14689.53 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M7397 | L-(−)-Malic acid suitable for cell culture, BioReagent, suitable for insect cell culture | 97-67-6 | 500G | ₹48485.18 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M6413 | L-(−)-Malic acid BioXtra, ≥95% | 97-67-6 | 25G | ₹5315.08 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M6413 | L-(−)-Malic acid BioXtra, ≥95% | 97-67-6 | 100G | ₹15165.83 | 2022-06-14 | Buy |
L-Malic acid Chemical Properties,Uses,Production
Description
L-Malic acid is nearly odorless (sometimes a faint, acrid odor) with a tart, acidic taste. It is nonpungent. May be prepared by hydration of maleic acid; by fermentation from sugars.
Chemical Properties
clear colourless solution
Occurrence
Occurs in maple sap, apple, melon, papaya, beer, grape wine, cocoa, sake, kiwifruit and chicory root.
Uses
L-Malic acid is used as a food additive, Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.
Definition
ChEBI: An optically active form of malic acid having (S)-configuration.
Preparation
L-Malic acid can be prepared by hydration of maleic acid; by fermentation from sugar.
General Description
L-Malic acid is an organic acid that is commonly found in wine. It plays an important role in wine microbiological stability.
Biochem/physiol Actions
L-Malic acid is a part of cellular metabolism. Its application is recognized in pharmaceutics. It is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia. It is used as a part of amino acid infusion. L-Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders. A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle.
Purification Methods
Crystallise S-malic acid (charcoal) from ethyl acetate/pet ether (b 55-56o), keeping the temperature below 65o. Or dissolve it by refluxing in fifteen parts of anhydrous diethyl ether, decant, concentrate to one-third volume and crystallise it at 0o, repeatedly to constant melting point. [Beilstein 3 IV 1123.]
L-Malic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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chevron_rightSupplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
HRV Global Life Sciences | +91-9820219686 +91-9820219686 | Telangana, India | 379 | 58 | Inquiry |
Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Avanscure Lifesciences Private Limited | 09599609443 | Haryana, India | 66 | 58 | Inquiry |
Padmavati Pharmachem | 08046031834 | Mumbai, India | 54 | 58 | Inquiry |
Nandlal Bankatlal Private Limited | 08047631198 | Mumbai, India | 30 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
Supplier | Advantage |
---|---|
JSK Chemicals | 58 |
HRV Global Life Sciences | 58 |
Clearsynth Labs | 58 |
CHEMSWORTH | 30 |
CLEARSYNTH LABS LTD. | 58 |
Avanscure Lifesciences Private Limited | 58 |
Padmavati Pharmachem | 58 |
Nandlal Bankatlal Private Limited | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Alfa Aesar | 58 |
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