Oxobutanedioic acid
- CAS No.
- 328-42-7
- Chemical Name:
- Oxobutanedioic acid
- Synonyms
- OXALOACETIC ACID;OXALACETIC ACID;2-OXOSUCCINIC ACID;OAA;oxalacetic;NSC 77688;NSC 284205;2-OXOSUCCINIC;OXLACETIC ACID;oxaloaceticaci
- CBNumber:
- CB0271682
- Molecular Formula:
- C4H4O5
- Molecular Weight:
- 132.07
- MOL File:
- 328-42-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/25 20:04:51
| Melting point | 161 °C (dec.)(lit.) |
|---|---|
| Boiling point | 163.94°C (rough estimate) |
| Density | 1.3067 (rough estimate) |
| vapor pressure | 0.003Pa at 20℃ |
| refractive index | 1.4000 (estimate) |
| Flash point | 88°C |
| storage temp. | -20°C |
| solubility | H2O: 100 mg/mL |
| form | powder |
| pka | 2.22(at 25℃) |
| color | White to off-white |
| PH | 3.05(1 mM solution);2.29(10 mM solution);1.68(100 mM solution) |
| Water Solubility | soluble |
| Merck | 14,6909 |
| BRN | 1705475 |
| Stability | Stable. Incompatible with strong oxidizing agents. Keep refrigerated. |
| LogP | -1.04 at 20℃ |
| CAS DataBase Reference | 328-42-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Oxalacetic acid(328-42-7) |
| EPA Substance Registry System | Oxalacetic acetic (328-42-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 3261 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29183000 | |||||||||
| NFPA 704 |
|
Oxobutanedioic acid price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | O7753 | Oxaloacetic acid powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97% (HPLC) | 328-42-7 | 5G | ₹10132.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | O9504 | Oxaloacetic acid Hybri-Max?, powder, suitable for hybridoma | 328-42-7 | 5G | ₹14310.65 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | O7753 | Oxaloacetic acid powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97% (HPLC) | 328-42-7 | 25G | ₹39218.98 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | O4126 | Oxaloacetic acid ≥97% (HPLC) | 328-42-7 | 1G | ₹4557.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | O7753 | Oxaloacetic acid powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97% (HPLC) | 328-42-7 | 100G | ₹115567.7 | 2022-06-14 | Buy |
Oxobutanedioic acid Chemical Properties,Uses,Production
Description
Oxaloacetic acid is an α-keto acid and a key component of cellular metabolism in its conjugate base form, oxaloacetate. Oxaloacetate reacts with acetyl-coenzyme A (acetyl-CoA; ) and water to form citrate in the first step of the citric acid cycle and is regenerated by oxidation of L-malate in the final step. It is an intermediate in gluconeogenesis that is formed in mitochondria via carboxylation of pyruvate and subsequently decarboxylated and phosphorylated to form phosphoenolpyruvate. It can be converted to aspartate via addition of an amino group from glutamate. Oxaloacetate (30 μmol/min per 100 g for 30 minutes, i.v.) reduces blood glutamate levels, severity of neurological dysfunction, and brain edema in a rat model of closed head injury.
Chemical Properties
off-white crystals
Uses
A four carbon dicarboxylic acid that is an intermediate in the citric acid cycle and glucogenesis. It has been shown to inhibit succinate dehydrogenase.
Definition
ChEBI: An oxodicarboxylic acid that is succinic acid bearing a single oxo group.
General Description
Oxaloacetic acid is a dicarboxylic acid. It is an intermediate in the citric acid cycle. It is highly soluble in water and is present ubiquitously. It is produced in the mitochondria by the action of pyruvate carboxylase on pyruvate. Breakdown products of oxaloacetate includes malate, pyruvate and aspartic acid.
Purification Methods
Crystallise it from boiling EtOAc, or from hot Me2CO/hot *C6H6. [Beilstein 3 IV 1808.]
Oxobutanedioic acid Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Anand Agencies | 91-20-24454597 | Maharashtra, India | 2337 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| HiMedia Laboratories | 91-22-61471919 | Maharashtra, India | 1843 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| OCEAN TRADING CORPORATION | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
| Central Drug House(P) Ltd. | 58 |
| Triveni chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| Anand Agencies | 58 |
| Sisco Research Laboratories Pvt. Ltd. | 58 |
| HiMedia Laboratories | 58 |
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