(S)-N-Fmoc-2-(2'-propylenyl)alanine

(S)-N-Fmoc-2-(2'-propylenyl)alanine Structure
CAS No.
288617-71-0
Chemical Name:
(S)-N-Fmoc-2-(2'-propylenyl)alanine
Synonyms
Fmoc-alpha-All-D-Ala-OH;Fmoc-α-Me-Gly(Allyl)-OH;(S)-N-FMOC-Α-ALLYLALANINE;(S)-N-Fmoc-A-Allylalanine;(S)-N-Fmoc-alpha-allylalanine;Fmoc-(S)-2-(2-propenyl)Ala-OH;Fmoc-(S)-2-(2-propenyl)alanine;(S)-N-Fmoc-α-2-n-propenylalanine;Fmoc-alpha-methyl-L-allylglycine;(S)-N-Fmoc-2-(2'-propenyl)alanine
CBNumber:
CB02485702
Molecular Formula:
C21H21NO4
Molecular Weight:
351.4
MOL File:
288617-71-0.mol
Modify Date:
2025/1/27 9:38:02

(S)-N-Fmoc-2-(2'-propylenyl)alanine Properties

Boiling point 564.3±45.0 °C(Predicted)
Density 1.224
storage temp. Inert atmosphere,Store in freezer, under -20°C
pka 3.81±0.11(Predicted)
form liquid
color pale yellow
InChIKey FNCSRFHDUZYOCR-NRFANRHFSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS09
Signal word  Warning
Hazard statements  H400
Precautionary statements  P273
Hazard Codes  N
Risk Statements  50
Safety Statements  61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
TSCA  No

(S)-N-Fmoc-2-(2'-propylenyl)alanine Chemical Properties,Uses,Production

Uses

Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake.

(S)-N-Fmoc-2-(2'-propylenyl)alanine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 72)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
Capot Chemical Co.,Ltd. +86-(0)57185586718 +86-13336195806 China 29730 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19552 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49732 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19908 58 Inquiry
Hunan Jibang Biological Technology Co., LTD +8613776644403 China 1804 58 Inquiry
TargetMol Chemicals Inc. United States 38636 58 Inquiry
Aladdin Scientific United States 57505 58 Inquiry
DAYANG CHEM (HANGZHOU) CO.,LTD +8617705817739 China 53881 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131957 58 Inquiry
(S)-N-Fmoc-2-(2'-propylenyl)alanine (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-4-pentenoic acid (S)-N-Fmoc-alpha-allylalanine (S)-N-(9-Fluorenylmethylcarbamate)-2-(2'-propylenyl)alanine Fmoc-alpha-methyl-L-allylglycine (S)-N-FMOC-Α-ALLYLALANINE (S)-N-Fmoc-α-2-n-propenylalanine Fmoc-(S)-2-(2-propenyl)alanine Fmoc-(S)-2-(2-propenyl)Ala-OH Fmoc-alpha-All-D-Ala-OH (2S)-2-(Fmoc-amino)-2-methyl-4-pentenoic acid (S)-N-Fmoc-A-Allylalanine 4-Pentenoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-, (2S)- N-α-(9-Fluorenylmethoxycarbonyl)-α-methyl-L-α-allylglycine (9H-Fluoren-9-yl)MethOxy]Carbonyl Alpha-Methyl-Gly(Allyl)-OH (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpent-4-enoic acid (S)-N-Fmoc-2-(2'-propenyl)alanine Fmoc-α-Me-Gly(Allyl)-OH Fmoc-(S)-2-(2-propenyl)Ala-OH 288617-71-0 α-Methyl Amino Acids