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tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate

tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Structure
CAS No.
1256584-75-4
Chemical Name:
tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate
Synonyms
Alectinib Impurity 6;Alectinib intermediate B;Alectinib intermediate I;Alectinib intermediate II;tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1...;6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate;tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate;tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate-10;tert-butyl 2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-6-isocyano-1H-indole-3-carboxylate ;2-Methyl-2-propanyl 6-cyano-2-[2-(4-ethyl-3-iodophenyl)-2-propany l]-1H-indole-3-carboxylate
CBNumber:
CB02624336
Molecular Formula:
C25H27IN2O2
Molecular Weight:
514.4
MOL File:
1256584-75-4.mol
MSDS File:
SDS
Modify Date:
2023/11/17 18:01:30
Request For Quotation

tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Properties

Boiling point 609.3±55.0 °C(Predicted)
Density 1.43±0.1 g/cm3(Predicted)
pka 14.00±0.30(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Chemical Properties,Uses,Production

Uses

tert-?Butyl 6-?Cyano-?2-?(2-?(4-?ethyl-?3-?iodophenyl)?propan-?2-?yl)?-?1H-?indole-?3-?carboxylate is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.

tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Suppliers

Global( 126)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9337 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
Jinan Finer Chemical Co., Ltd +86-531-88989536 +86-15508631887 China 2967 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
Shanghai Rochi Pharmaceutical Co.,Ltd. 21-38751876 +8615000076078 China 431 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
Senova Technology Co. Ltd. +86-0755-86703119 +8618503098836 China 350 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Capot Chemical Co.,Ltd. 60
Hangzhou FandaChem Co.,Ltd. 55
ATK CHEMICAL COMPANY LIMITED 60
Jinan Finer Chemical Co., Ltd 58
career henan chemical co 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 58
Shanghai Rochi Pharmaceutical Co.,Ltd. 58
AFINE CHEMICALS LIMITED 58
Senova Technology Co. Ltd. 58

1256584-75-4(tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate)Related Search:

4-Morpholinopiperidine Alectinib
tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate-10 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate 2-Methyl-2-propanyl 6-cyano-2-[2-(4-ethyl-3-iodophenyl)-2-propany l]-1H-indole-3-carboxylate 6-Cyano-2-[1-(4-ethyl-3-iodophenyl)-1-methylethyl]-1H-indole-3-carboxylic acid 1,1-dimethylethyl ester Alectinib Impurity 6 TERT-BUTYL 6-CYANO-2- (2-(4-ETHYL-3-IODOPHENYL)PROPAN-2-YL) -1H-INDOLE-3-CARBOXYLATE _ 1256584-75-4 tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate/tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate 1H-Indole-3-carboxylic acid, 6-cyano-2-[1-(4-ethyl-3-iodophenyl)-1-methylethyl]-, 1,1-dimethylethyl ester Alectinib intermediate B Alectinib intermediate II tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1... Alectinib intermediate I tert-butyl 2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-6-isocyano-1H-indole-3-carboxylate 1256584-75-4 125684-75-4 1256584-75-4