ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
![N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Structure](CAS/20150408/GIF/289472-81-7.gif)
- CAS No.
- 289472-81-7
- Chemical Name:
- N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
- Synonyms
- Bortezomib EP IMP M;Bortezomib USP IMP J;Bortezomib Impurity D;Bortezomib Impurity J;Bortezomib Impurity 48;Bortezomib USP Impurity J;BortezomibHydroxy(1S,2S)-Isomer;Bortezomib USP Related Compoud J;(S)-Hydroxy Des(boric Acid) BortezoMib;(S,S)-Bortezomib Hydroxyisopentyl Amide Analog
- CBNumber:
- CB02661665
- Molecular Formula:
- C19H24N4O3
- Molecular Weight:
- 356.42
- MOL File:
- 289472-81-7.mol
- Modify Date:
- 2023/5/15 10:43:55
N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Properties
Boiling point | 672.0±55.0 °C(Predicted) |
---|---|
Density | 1.199±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), Methanol (Slightly) |
pka | 11.90±0.46(Predicted) |
form | Solid |
color | White to Off-White |
N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Chemical Properties,Uses,Production
Uses
(S)-Hydroxy Des(boric Acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.
N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 69)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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OPULENT PHARMA | +91-9106692785 +91-9106692785 | Gujarat, India | 479 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Sai Traders | 08046046461 | Ahmedabad, India | 293 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
sgtlifesciences pvt ltd | +8617013299288 | China | 12382 | 58 | Inquiry |
LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
China National Standard Pharmaceutical Corporation Limited | +8615391658522 | China | 11927 | 58 | Inquiry |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | China | 8474 | 58 | Inquiry |
289472-81-7(N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide)Related Search:
2,3-Pyrazinedicarboxylic acid
Bortezomib Impurity 35
Bortezomib Impurity 23
tert-Butyl Tosylate
DISCONTINUED
Bortezomib Impurity 5
1-Chloro-2-methylpropane
Bortezomib Impurity 45
BOC-D-Phenylalanine
bortezoMib iMpurity H
Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-
(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-
N-((S)-1-(((R)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
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2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-
(S)-Hydroxy Des(boric Acid) BortezoMib
(N-[(1S)-1-hydroxy-3-Methylbutyl]-Nα-(pyrazin-2-ylcarbonyl)-L-phenylalaninaMide
Bortezomib Impurity 48
Bortezomib Impurity J
N-[(2S)-1-[[(1S)-1-hydroxy-3-methylbutyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide
Bortezomib USP IMP J
Bortezomib Impurity D
Bortezomib USP Related Compoud J
N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-Pyrazinecarboxamide
N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-pyrazi
Bortezomib USP Impurity J
Bortezomib Related Compund J/ (S,S)-Bortezomib Hydroxyisopentyl Amide Analog (Bortezomib Hydroxy S,S-Isomer Impurity)
BortezomibHydroxy(1S,2S)-Isomer
(S,S)-Bortezomib Hydroxyisopentyl Amide Analog
Bortezomib EP IMP M
N-[(2S)-1-[[(1S)-1-hydroxy-3-methylbutyl]amino]-1-oxo-3-phenylprop
N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenyl
289472-81-7
Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals