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ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide

N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide

N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Structure
CAS No.
289472-81-7
Chemical Name:
N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
Synonyms
Bortezomib EP IMP M;Bortezomib USP IMP J;Bortezomib Impurity D;Bortezomib Impurity J;Bortezomib Impurity 48;Bortezomib USP Impurity J;BortezomibHydroxy(1S,2S)-Isomer;Bortezomib USP Related Compoud J;(S)-Hydroxy Des(boric Acid) BortezoMib;(S,S)-Bortezomib Hydroxyisopentyl Amide Analog
CBNumber:
CB02661665
Molecular Formula:
C19H24N4O3
Molecular Weight:
356.42
MOL File:
289472-81-7.mol
Modify Date:
2023/5/15 10:43:55
Request For Quotation

N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Properties

Boiling point 672.0±55.0 °C(Predicted)
Density 1.199±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka 11.90±0.46(Predicted)
form Solid
color White to Off-White

N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Chemical Properties,Uses,Production

Uses

(S)-Hydroxy Des(boric Acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.

N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Preparation Products And Raw materials

Raw materials

Preparation Products

N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Suppliers

Global( 69)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
OPULENT PHARMA +91-9106692785 +91-9106692785 Gujarat, India 479 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Sai Traders 08046046461 Ahmedabad, India 293 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
sgtlifesciences pvt ltd +8617013299288 China 12382 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Supplier Advantage
OPULENT PHARMA 58
SynZeal Research Pvt Ltd 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Sai Traders 58
CLEARSYNTH LABS LTD. 58
sgtlifesciences pvt ltd 58
LEAP CHEM CO., LTD. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
China National Standard Pharmaceutical Corporation Limited 58
Wuhan Topule Biopharmaceutical Co., Ltd 58

289472-81-7(N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide)Related Search:

2,3-Pyrazinedicarboxylic acid Bortezomib Impurity 35 Bortezomib Impurity 23 tert-Butyl Tosylate DISCONTINUED Bortezomib Impurity 5
1-Chloro-2-methylpropane Bortezomib Impurity 45 BOC-D-Phenylalanine bortezoMib iMpurity H Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- N-((S)-1-(((R)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Bortezomib Impurity 47 HCl 1-Bromo-2-methylpropane
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2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- (S)-Hydroxy Des(boric Acid) BortezoMib (N-[(1S)-1-hydroxy-3-Methylbutyl]-Nα-(pyrazin-2-ylcarbonyl)-L-phenylalaninaMide Bortezomib Impurity 48 Bortezomib Impurity J N-[(2S)-1-[[(1S)-1-hydroxy-3-methylbutyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide Bortezomib USP IMP J Bortezomib Impurity D Bortezomib USP Related Compoud J N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-Pyrazinecarboxamide N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-pyrazi Bortezomib USP Impurity J Bortezomib Related Compund J/ (S,S)-Bortezomib Hydroxyisopentyl Amide Analog (Bortezomib Hydroxy S,S-Isomer Impurity) BortezomibHydroxy(1S,2S)-Isomer (S,S)-Bortezomib Hydroxyisopentyl Amide Analog Bortezomib EP IMP M N-[(2S)-1-[[(1S)-1-hydroxy-3-methylbutyl]amino]-1-oxo-3-phenylprop N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenyl 289472-81-7 Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals