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PERUVOSIDE

PERUVOSIDE Structure
CAS No.
1182-87-2
Chemical Name:
PERUVOSIDE
Synonyms
Enordin;encordin;Pervoside;peruvosid;PERUVOSIDE;(22)-enolide;PERUVOSIDE(RG);Peruvoside (90%);PERUVOSIDE USP/EP/BP;cannogeninthevetoside
CBNumber:
CB0266619
Molecular Formula:
C30H44O9
Molecular Weight:
548.66
MOL File:
1182-87-2.mol
Modify Date:
2023/8/25 11:46:16

PERUVOSIDE Properties

Melting point 161-164°C
alpha D22 -71.7° (c = 1.54 in methanol)
Boiling point 540.83°C (rough estimate)
Density 1.1277 (rough estimate)
refractive index 1.5500 (estimate)
storage temp. 2-8°C
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka 12.92±0.70(Predicted)
form powder
color light yellow

SAFETY

Risk and Safety Statements

Hazard Codes  T
Risk Statements  23/24/25
Safety Statements  36/37/39-45
WGK Germany  3
RTECS  FH4915000
Toxicity cat,LD50,intravenous,145ug/kg (0.145mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGCARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)CARDIAC: CHANGE IN RATE,Archives Internationales de Pharmacodynamie et de Therapie. Vol. 126, Pg. 412, 1960.

PERUVOSIDE Chemical Properties,Uses,Production

Uses

Peruvoside is a cardiac glycoside with the same inotropic and chronotropic effects on heart function as Ouabain (O714500).

Enzyme inhibitor

This cardiotonic glycoside or cardenoide (FW = 548.67 g/mol; CAS 1182- 87-2), named systematically as (3b,5b)-3-(6-deoxy-3-O-methyl-a-Lglucopyranosyl)oxyl-14-hydroxy-19-oxocard-20(22)-enolide, a component of neriperside from Thevetia neriifolia (yellow oleander) resembles oubain in its inotropic (force of contraction) and chronotropic (rate of contraction) effects on heart function. Orally administered peruvoside is effective in treating congestive heart failure. Note the structural similarities of the aglycon to digitoxigenin. Target(s): Na+ /K+ -exchanging ATPase.

PERUVOSIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 52)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Shaanxi Haibo Biotechnology Co., Ltd +undefined18602966907 China 1000 58 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3777 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24639 58 Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +8617865335152 China 10978 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
ABCR GmbH & CO. KG 49 721 95061 0 Germany 6846 75 Inquiry
Naturewill Biotechnology Co., Ltd. 18113192475 18113192475 China 4999 58 Inquiry
Wuhan Huangzhen Biochemical Co., Ltd 13795480948 13795480948 China 4958 58 Inquiry
Chengdu Push Bio-Technology Co., Ltd. 028-85370565-229 18080489829 China 9369 60 Inquiry
PERUVOSIDE (22)-enolide (3β,5β)-3-(6-Deoxy-3-O-methyl-α-L-glucopyranosyl]oxyl)-14-hydroxy-19-oxocard-20(22)-enolide 3β-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxo-5β,14β-card-20(22)-enolide Cannogenin α-L-thevetoside Enordin Pervoside (3β,5β)-3-[(6-Deoxy-3-O-Methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide Peruvoside (90%) (3beta,5beta)-3-[(6-deoxy-3-O-methyl-alpha-L\-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide PERUVOSIDE FROM THEVETIA NERIIFOLIA PERUVOSIDE(RG) (3-beta,5-beta)-oxy-19-oxo 3-((6-deoxy-3-o-methyl-alpha-l-glucopyranosyl)oxy)-14-hydroxy-19-oxo-card-20 cannogeninalpha-l-thevetoside cannogeninthevetoside card-20(22)-enolide,3-((6-deoxy-3-o-methyl-alpha-l-glucopyranosyl)oxy)-14-hydr encordin peruvosid CANNOGENNIN-ALPHA-L-THEVETOSIDE [3BETA,5BETA]-3-[6-DEOXY-3-O-METHYL-ALPHA-L-GLUCOPYRANOSYL)OXYL]-14-HYDROXY-19-OXOCARD-20[22]-ENOLIDE PERUVOSIDE USP/EP/BP (3S,5R,8R,9S,10R,13R,14S,17R)-3-[(2R,3S,4R,5S,6S)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy-14-hydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-10-carbaldehyde Card-20(22)-enolide, 3-[(6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxo-, (3β,5β)- 1182-87-2 C30H44O9