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Axitinib Impurity B

Axitinib Impurity B Structure
CAS No.
944835-85-2
Chemical Name:
Axitinib Impurity B
Synonyms
Axitinib impurity G;Axitinib Impurity e;AxitinibimChemicalbookpurityG;2-(1H-indazol-6-ylthio)-N-Methyl- BenzaMide;BenzaMide, 2-(1H-indazol-6-ylthio)-N-Methyl-;2-(1H-Indazol-6-ylsulfanyl)-N-methylbenzamide;Axitinib Impurity 3/2-((1H-indazol-6-yl)thio)-N-methylbenzamide
CBNumber:
CB02681085
Molecular Formula:
C15H13N3OS
Molecular Weight:
283.35
MOL File:
944835-85-2.mol
Modify Date:
2024/4/29 14:28:21
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Axitinib Impurity B Properties

Melting point >148°C (dec.)
Boiling point 555.7±30.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
storage temp. 4°C, Inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka 13.02±0.40(Predicted)
form Solid
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

Axitinib Impurity B Chemical Properties,Uses,Production

Uses

2-(1H-Indazol-6-ylthio)-N-methylbenzamide is a useful intermediate for the preparation of axitinib; an antitumor agent.

Axitinib Impurity B Preparation Products And Raw materials

Raw materials

6-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole 6-Aminoindazole 6-Iodo-1H-indazole 2,2'-dithiobis[N-methylbenzamide] 2-mercapto-N-methylbenzamide
2,2'-dithiodibenzoyl chloride 2,2'-Dithiosalicylic acid
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Preparation Products

BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl-

Axitinib Impurity B Suppliers

Global( 68)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20361 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Baoji Guokang Healthchem co.,ltd +8615604608665 15604608665 CHINA 9427 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
Zhengzhou Anbu Chem Co.,Ltd +86-0371-88006763; +8615988602810 China 3000 58 Inquiry
Qingdao Minzhi Yijie new material Co., LTD +86-13589435123 +86-13589435123 China 240 58 Inquiry
Supplier Advantage
Pharma Affiliates 58
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Henan Fengda Chemical Co., Ltd 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
Baoji Guokang Healthchem co.,ltd 58
China National Standard Pharmaceutical Corporation Limited 58
Zhengzhou Anbu Chem Co.,Ltd 58
Qingdao Minzhi Yijie new material Co., LTD 58

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2-(1H-indazol-6-ylthio)-N-Methyl- BenzaMide BenzaMide, 2-(1H-indazol-6-ylthio)-N-Methyl- Axitinib Impurity e Axitinib impurity G Axitinib Impurity 3/2-((1H-indazol-6-yl)thio)-N-methylbenzamide 2-(1H-Indazol-6-ylsulfanyl)-N-methylbenzamide AxitinibimChemicalbookpurityG 944835-85-2 Intermediate