DIFETHIALONE

DIFETHIALONE Structure
CAS No.
104653-34-1
Chemical Name:
DIFETHIALONE
Synonyms
LM2219;Baraki;RODILON;Hsdb 7119;GENERATION;Difethiarol;ifethialone;DIFETHIALONE;Difethialone-13C6;Difethialone [iso]
CBNumber:
CB0304070
Molecular Formula:
C31H23BrO2S
Molecular Weight:
539.48
MOL File:
104653-34-1.mol
Modify Date:
2024/12/18 13:37:16

DIFETHIALONE Properties

Melting point 203-227°
Boiling point 658.3±55.0 °C(Predicted)
Density 1.3614 g/cm3(Temp: 25 °C)
solubility Chloroform: slightly soluble; Methanol: slightly soluble
form A solid
pka 4.50±1.00(Predicted)
EPA Substance Registry System Difethialone (104653-34-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS06,GHS09
Signal word  Danger
Hazard statements  H300-H310-H330-H360D-H372-H410
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P260-P264-P270-P314-P501-P273-P391-P501
RIDADR  UN2588 (Pesticide, solid, poi- sonous, n.o.s.); UN2902 (Pesticide, liquid, poisonous, n.o.s.)
HS Code  29349990
Hazardous Substances Data 104653-34-1(Hazardous Substances Data)
Toxicity LD50 orally in male, female rats, mice (mg/kg): 0.62, 0.42, 0.52, 0.43 (non-resistant); 0.27, 0.39, 0.46, 0.52 (warfarin resistant); LD50 in hare: 0.75 mg/kg; LC50 in mallard duck, bobwhite quail (ppm): 1.94, 0.56; LD50 at 48 hrs in daphnia magna, bluegill sunfish, rainbow trout (mg/l): 4.4, 110, 67 (Lechevin)
NFPA 704
0
4 0

DIFETHIALONE Chemical Properties,Uses,Production

Description

Difethialone[104653-34-1], 3-[(1RS,3RS; 1RS,3SR)-3- (4 -bromobiphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthyl]- 4-hydroxy-1-benzothiin-2-one, C31H23BrO2S, MW 539.5, mp 233–236 ?C, is a slightly yellowish powder which is practically insoluble in water, moderately soluble in ethanol, methanol, hexane, acetone, readily soluble in chloroform, dimethylformamide [9, p. 393].

Uses

Difethialone is an anticoagulant rodenticide widely used to control rodent infestations.

Preparation

Difethialone is made by condensation of 4-hydroxy-2H- 1-benzothiapyran-2-one with 3-(4 -bromo-4-biphenyl)-1,2, 3,4-tetrahydro-1-naphthol in acetic acid containing concentrated sulfuric acid (62).

Agricultural Uses

Rodenticide, Pesticide: Introduced in 1986, this second-generation anticoagulant rodenticide (member of the hydroxy-4-benzothiopyranone family) is used to control mice and rats, including those resistant to first-generation anticoagulants. Not approved for use in most EU countries. Approved for use in the U.S.

Trade name

LM-2219®; PROTECTA RAT BAIT STATION®; VETERAN PELLET®; VETERAN WAX BLOCK®

DIFETHIALONE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 61)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
AKASH PHARMA EXPORTS +91-9388123451 +91-9846039283 Kerela, India 470 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
SUZHOU SENFEIDA CHEMICAL CO.,LTD +86-0512-83500002 +8618501500038 China 26362 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20235 58 Inquiry
SHANGHAI KEAN TECHNOLOGY CO., LTD. +8613817748580 China 40066 58 Inquiry
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. +8618950047208 China 43416 58 Inquiry
DAYANG CHEM (HANGZHOU) CO.,LTD +8617705817739 China 53881 58 Inquiry
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780 China 233051 58 Inquiry
Shanghai Aitixi Biotechnology Co., Ltd 18721763493 18721763493 China 973 58 Inquiry
Artis Biotech Co. Ltd. 19138486554 18108108965 China 5329 58 Inquiry
LM2219 DIFETHIALONE GENERATION 2H-1-Benzothiopyran-2-one, 3-3-(4-bromo1,1-biphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl-4-hydroxy- 2H-1-Benzothiapyran-2-one, 3-(3-(4'-bromo(1,1'-biphenyl)-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl)-4-hydroxy- RODILON 2h-1-benzothiopyran-2-one,3-(3-(4’-bromo(1,1’-biphenyl)-4-yl)-1,2,3,4-tetrahyd ro-1-naphthalenyl)-4-hydroxy- 3-(3-(4'-Bromo(1,1'-biphenyl)-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl)-4-hydroxy-2H-1-benzothiapyran-2-one Difethialone [iso] Hsdb 7119 3-[3-(4'-BroMo[1,1'-biphenyl]-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl]-4-hydroxy-2H-1-benzothiopyran-2-one Baraki Difethiarol 3-[3-[4-(4-bromophenyl)phenyl]-1,2,3,4-tetrahydronaphthalen-1-yl]-2-hydroxythiochromen-4-one Difethialone (Mixture of Diastereomers) Difethialone-d4 (Mixture of Diastereomers) Difethialone-13C6 ifethialone 3-[3-(4′-bromo[1,1′biphenyl]-4-yl)-1,2,3,4-tetrahydronaphth-1-yl]-4-hydroxy-2H-1-benzothiopyran-2-one (Difethialone) 104653-34-1 C31H23BrO2S