DIFETHIALONE

DIFETHIALONE Structure
CAS No.
104653-34-1
Chemical Name:
DIFETHIALONE
Synonyms
LM2219;Baraki;RODILON;Hsdb 7119;GENERATION;Difethiarol;ifethialone;DIFETHIALONE;Difethialone-13C6;Difethialone [iso]
CBNumber:
CB0304070
Molecular Formula:
C31H23BrO2S
Molecular Weight:
539.48
MOL File:
104653-34-1.mol
Modify Date:
2023/6/8 9:03:05

DIFETHIALONE Properties

Melting point 203-227°
Boiling point 658.3±55.0 °C(Predicted)
Density 1.3614 g/cm3(Temp: 25 °C)
solubility Chloroform: slightly soluble; Methanol: slightly soluble
form A solid
pka 4.50±1.00(Predicted)
EPA Substance Registry System Difethialone (104653-34-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS06,GHS09
Signal word  Danger
Hazard statements  H300-H310-H330-H360D-H372-H410
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P260-P264-P270-P314-P501-P273-P391-P501
RIDADR  UN2588 (Pesticide, solid, poi- sonous, n.o.s.); UN2902 (Pesticide, liquid, poisonous, n.o.s.)
HS Code  29349990
Toxicity LD50 orally in male, female rats, mice (mg/kg): 0.62, 0.42, 0.52, 0.43 (non-resistant); 0.27, 0.39, 0.46, 0.52 (warfarin resistant); LD50 in hare: 0.75 mg/kg; LC50 in mallard duck, bobwhite quail (ppm): 1.94, 0.56; LD50 at 48 hrs in daphnia magna, bluegill sunfish, rainbow trout (mg/l): 4.4, 110, 67 (Lechevin)
NFPA 704
0
4 0

DIFETHIALONE Chemical Properties,Uses,Production

Description

Difethialone[104653-34-1], 3-[(1RS,3RS; 1RS,3SR)-3- (4 -bromobiphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthyl]- 4-hydroxy-1-benzothiin-2-one, C31H23BrO2S, MW 539.5, mp 233–236 ?C, is a slightly yellowish powder which is practically insoluble in water, moderately soluble in ethanol, methanol, hexane, acetone, readily soluble in chloroform, dimethylformamide [9, p. 393].

Uses

Difethialone is an anticoagulant rodenticide widely used to control rodent infestations.

Preparation

Difethialone is made by condensation of 4-hydroxy-2H- 1-benzothiapyran-2-one with 3-(4 -bromo-4-biphenyl)-1,2, 3,4-tetrahydro-1-naphthol in acetic acid containing concentrated sulfuric acid (62).

Agricultural Uses

Rodenticide, Pesticide: Introduced in 1986, this second-generation anticoagulant rodenticide (member of the hydroxy-4-benzothiopyranone family) is used to control mice and rats, including those resistant to first-generation anticoagulants. Not approved for use in most EU countries. Approved for use in the U.S.

Trade name

LM-2219®; PROTECTA RAT BAIT STATION®; VETERAN PELLET®; VETERAN WAX BLOCK®

DIFETHIALONE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 51)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
AKASH PHARMA EXPORTS +91-9388123451 +91-9846039283 Kerela, India 470 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Shenzhen Nexconn Pharmatechs Ltd +86-755-89396905 +86-15013857715 China 10259 58 Inquiry
Finetech Industry Limited +86-27-87465837 +8618971612321 China 9626 58 Inquiry
SUZHOU SENFEIDA CHEMICAL CO.,LTD +86-0512-83500002 +8615195660023 China 10814 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20361 58 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28118 58 Inquiry
Shanghai Aitixi Biotechnology Co., Ltd 18721763493 18721763493 China 970 58 Inquiry
Nantong Zhonghe Chemical New Materials Co., Ltd 13003551299 13003551299 China 7567 58 Inquiry
ShangHai Anpel Co, Ltd. 18501792038; 18501792038 China 9614 58 Inquiry
LM2219 DIFETHIALONE GENERATION 2H-1-Benzothiopyran-2-one, 3-3-(4-bromo1,1-biphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl-4-hydroxy- 2H-1-Benzothiapyran-2-one, 3-(3-(4'-bromo(1,1'-biphenyl)-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl)-4-hydroxy- RODILON 2h-1-benzothiopyran-2-one,3-(3-(4’-bromo(1,1’-biphenyl)-4-yl)-1,2,3,4-tetrahyd ro-1-naphthalenyl)-4-hydroxy- 3-(3-(4'-Bromo(1,1'-biphenyl)-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl)-4-hydroxy-2H-1-benzothiapyran-2-one Difethialone [iso] Hsdb 7119 3-[3-(4'-BroMo[1,1'-biphenyl]-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl]-4-hydroxy-2H-1-benzothiopyran-2-one Baraki Difethiarol 3-[3-[4-(4-bromophenyl)phenyl]-1,2,3,4-tetrahydronaphthalen-1-yl]-2-hydroxythiochromen-4-one Difethialone (Mixture of Diastereomers) Difethialone-d4 (Mixture of Diastereomers) Difethialone-13C6 ifethialone 104653-34-1 C31H23BrO2S