UCM05

CAS No.: 1094451-90-7

Chemical Name:: UCM05

Synonyms: UCM05;G 28UCM;UCM05(G 28UCM);Benzoic acid, 3,4,5-trihydroxy-, 1,1'-(1,3-naphthalenediyl) ester;3-(3,4,5-Trihydroxybenzoyloxy)naphthalen-1-yl 3,4,5-trihydroxybenzoate

CBNumber:: CB03067587

Molecular Formula:: C24H16O10

Molecular Weight:: 464.38

MOL File:: 1094451-90-7.mol

Modify Date:: 2024/7/2 8:54:57

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UCM05 Properties

Boiling point	895.1±65.0 °C(Predicted)
Density	1.652±0.06 g/cm3(Predicted)
solubility	DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 12 mg/ml; Ethanol:PBS (pH 7.2) (1:40): 0.02 mg/ml
form	A crystalline solid
pka	7.50±0.25(Predicted)
color	Off-white to light brown

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501

NFPA 704

	0
2		0

UCM05 Chemical Properties,Uses,Production

Uses

UCM05 is an inhibitor of fatty acid synthase that strongly suppresses the growth of human breast cancer cell lines (IC50 = 21 μM for SK-BR-3 cells). It does not alter carnitine palmitoyltransferase 1 activity or induce weight loss in mice. UCM05 can reduce cleavage of poly(ADP-ribose) polymerase, phosphorylation of HER2, Akt, and ERK1/2, and growth of established xenografts in vivo. UCM05 also blocks the GTP-binding site of the cell division protein FtsZ from Bacillus, preventing bacterial division.[Cayman Chemical]

UCM05 Preparation Products And Raw materials

Raw materials

1,3-DIHYDROXYNAPHTHALENE

Preparation Products

UCM05 Suppliers

Global( 33)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
LEAPCHEM CO., LTD.	+86-852-30606658	China	43348	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd.	+86-18521732826	China	48465	58	Inquiry
RD International Technology Co., Limited	18024082417	China	9268	58	Inquiry
Jinan Jiuli Biotechnology Co. , Ltd.	15865264761	China	3045	58	Inquiry
Bide Pharmatech Ltd.	400-1647117 13681763483	China	62163	58	Inquiry
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	China	8141	58	Inquiry
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	China	4182	55	Inquiry
Cayman Chemical Company	(800) 364-9897	United States	6618	81	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	58
RD International Technology Co., Limited	58
Jinan Jiuli Biotechnology Co. , Ltd.	58
Bide Pharmatech Ltd.	58
MedBioPharmaceutical Technology Inc	58
Tianjin Kailiqi Biotechnology Co., Ltd.	55
Cayman Chemical Company	81

UCM05 G 28UCM 3-(3,4,5-Trihydroxybenzoyloxy)naphthalen-1-yl 3,4,5-trihydroxybenzoate Benzoic acid, 3,4,5-trihydroxy-, 1,1'-(1,3-naphthalenediyl) ester UCM05(G 28UCM) 1094451-90-7