UCM05
UCM05
- CAS:
- 1094451-90-7
- MF:
- C24H16O10
- MW:
- 464.38
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Properties
- Boiling point:
- 895.1±65.0 °C(Predicted)
- Density
- 1.652±0.06 g/cm3(Predicted)
- solubility
- DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 12 mg/ml; Ethanol:PBS (pH 7.2) (1:40): 0.02 mg/ml
- form
- A crystalline solid
- pka
- 7.50±0.25(Predicted)
- color
- Off-white to light brown
Safety Information
Use
UCM05 is an inhibitor of fatty acid synthase that strongly suppresses the growth of human breast cancer cell lines (IC50 = 21 μM for SK-BR-3 cells). It does not alter carnitine palmitoyltransferase 1 activity or induce weight loss in mice. UCM05 can reduce cleavage of poly(ADP-ribose) polymerase, phosphorylation of HER2, Akt, and ERK1/2, and growth of established xenografts in vivo. UCM05 also blocks the GTP-binding site of the cell division protein FtsZ from Bacillus, preventing bacterial division.[Cayman Chemical]
1 India supplier list of "UCM05"
- Product Name:G 28UCM
- Products Intro:Purity: >=98%(HPLC) | Package: $23.9/1mg;$98.9/5mg;$167.9/10mg;$345.9/25mg;$543.9/50mg;$1399.9/100mg;$2799.9/25 | CustNote: 98%(HPLC)
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies