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PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE

PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Structure
CAS No.
207671-42-9
Chemical Name:
PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE
Synonyms
LUTIDINIC ACID MONOHYDRATE;PYRIDINE-2,4-DICARBOXYLIC ACID HYDRATE;2,4-PYRIDINECARBOXYLIC ACID MONOHYDRATE;2,4-PYRIDINEDICARBOXYLIC ACID MONOHYDRATE;PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE;2,4-Pyridinedicarboxylicacid, hydrate (1:1);2,4-Pyridinedicarboxylic acid Monohydrate 98%
CBNumber:
CB0356837
Molecular Formula:
C7H7NO5
Molecular Weight:
185.13
MOL File:
207671-42-9.mol
Modify Date:
2023/6/8 9:01:59

PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Properties

Melting point 246-248 °C (dec.)(lit.)
storage temp. Store at -20°C
solubility DMSO: 1.4 mg/ml; PBS (pH 7.2): 0.2 mg/ml
form A crystalline solid
BRN 131631

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
NFPA 704
0
2 0

PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) P63395 2,4-Pyridinedicarboxylic acid monohydrate 98% 207671-42-9 5G ₹3453.18 2022-06-14 Buy
Product number Packaging Price Buy
P63395 5G ₹3453.18 Buy

PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Chemical Properties,Uses,Production

Description

2,4-Pyridinedicarboxylic Acid (2,4-PDCA) is a compound that structurally mimics 2-oxoglutarate (2-OG, also known as α-ketoglutarate) and chelates zinc, thus affecting a range of enzymes. As a 2-OG mimic, it blocks the activity of 2-OG oxygenases, which include certain lysine demethylases and a variety of hydroxylases (e.g., prolyl, collagen, lysyl). 2,4-PDCA inhibits several Jumonji domain-containing lysine demethylases when used at low micromolar concentrations. Through its effects on hydroxylases, including prolyl hydroxlase 1 (IC50 = 1.5 μM), 2,4-PDCA modulates hypoxia-inducible factor turnover, collagen synthesis, and plant cell wall formation. It can inhibit zinc-dependent enzymes, like metallo-β-lactamase. 2,4-PDCA also affects and is translocated by organic anion transporters.

PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Suppliers

Global( 48)Suppliers
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Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30241 58 Inquiry
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PYRIDINE-2,4-DICARBOXYLIC ACID HYDRATE 2,4-PYRIDINEDICARBOXYLIC ACID MONOHYDRATE 2,4-PYRIDINECARBOXYLIC ACID MONOHYDRATE PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE LUTIDINIC ACID MONOHYDRATE 2,4-Pyridinedicarboxylicacid, hydrate (1:1) 2,4-Pyridinedicarboxylic acid Monohydrate 98% 207671-42-9 C7H5NO4H2O Building Blocks C7 and C8 Heterocyclic Building Blocks Pyridines Building Blocks C7 Chemical Synthesis Heterocyclic Building Blocks C7 and C8 Heterocyclic Building Blocks Pyridines