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PROTOVERATRINE B

PROTOVERATRINE B Structure
CAS No.
124-97-0
Chemical Name:
PROTOVERATRINE B
Synonyms
yrate);veratetrin;neoprotoveratrin;PROTOVERATRINE B;NEOPROTOVERATRINE;PROTOVERATRINE B (RG);PROTOVERATRINE A (RG)(CALL);4-beta,6-alpha,7-alpha,14,15-alpha-16-beta,20-octol,4,9-epoxy-cevane-3-bet;6,7-diacetate3-(threo-(+)-2,3-dihydroxy-2-methylbutyrate)15-((-)-2-methylbut;4α,9-Epoxycevane-3β,4β,6α,7α,14,15α,16β,20-octol 6,7-diacetate 3-[(2R,3R)-2,3-dihydroxy-2-methylbutanoate]15-[(R)-2-methylbutanoate]
CBNumber:
CB0376499
Molecular Formula:
C41H63NO15
Molecular Weight:
809.94
MOL File:
124-97-0.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

PROTOVERATRINE B Properties

Melting point 268-270°C
alpha D25 -37° (pyridine); D25 -3.5° (chloroform)
Boiling point 755.18°C (rough estimate)
Density 1.1826 (rough estimate)
refractive index 1.6220 (estimate)
storage temp. 2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
pka 10.73±0.70(Predicted)

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
RIDADR  1544
WGK Germany  3
RTECS  FL5750000
HazardClass  6.1(a)
PackingGroup  II
Toxicity LD50 s.c. in male mice: 0.21 mg/kg (Tanaka)

PROTOVERATRINE B Chemical Properties,Uses,Production

Description

Also present in Veratrum album, this closely allied alkaloid may be separated from the preceding base by chromatography. It also yields colourless crystals from EtOH and is laevorotatory with [α]29D&o - 39.8° (pyridine) or - 3.5° (CHCI3). In this case, alkaline hydrolysis gives protoverine, two moles of acetic acid, one mole of (-)-2-methylbutyric acid and one mole of 2: 3-dihydroxy-2- methylbutyric acid. It may be distinguished from protoveratrine A by giving a green colour with H2S04. It also forms a complex with maleic acid having m.p. 222.2°C; [α]29D&o - 27.3°.

References

Stoll, Seebeck., Helv. Chim. Acta., 36,718 (1953)

PROTOVERATRINE B Preparation Products And Raw materials

Raw materials

Preparation Products

PROTOVERATRINE B Suppliers

Global( 17)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-81138252 +86-18789408387 China 2077 58 Inquiry
ABCR GmbH & CO. KG 49 721 95061 0 Germany 6846 75 Inquiry
Shaanxi Dideu Medichem Co. Ltd 029-81124267 15229202216 China 10011 58 Inquiry
ChromaDex 949 419 0288 United States 2501 76 Inquiry
Pfaltz & Bauer, Inc. (800) 225-5172 United States 6830 72 Inquiry
Apin Chemicals Ltd. +44 1235 832515 United Kingdom 6811 42 Inquiry
INDOFINE Chemical Company, Inc. 1 888 463 6346 United States 6177 69 Inquiry
MP Biomedicals, Inc. 949 833 2500 United States 6566 81 Inquiry
Service Chemical Inc. 888-895-6920 Germany 6373 71 Inquiry
BBT INC 022-58613671 58613672 China 3517 47 Inquiry
[3beta(2R,3R),4alpha,6alpha,7alpha,15alpha(R),16beta]-4,9-epoxycevane-3,4,6,7,14,15,16,20-octol 6,7-diacetate 3-(2,3-dihydroxy-2-methylbutyrate) 15-(2-methylbutyrate) PROTOVERATRINE B (RG) PROTOVERATRINE B NEOPROTOVERATRINE 4-beta,6-alpha,7-alpha,14,15-alpha-16-beta,20-octol,4,9-epoxy-cevane-3-bet 4α,9-Epoxycevane-3β,4β,6α,7α,14,15α,16β,20-octol 6,7-diacetate 3-[(2R,3R)-2,3-dihydroxy-2-methylbutanoate]15-[(R)-2-methylbutanoate] PROTOVERATRINE A (RG)(CALL) 6,7-diacetate3-(threo-(+)-2,3-dihydroxy-2-methylbutyrate)15-((-)-2-methylbut neoprotoveratrin veratetrin yrate) Cevane-3,4,6,7,14,15,16,20-octol, 4,9-epoxy-, 6,7-diacetate 3-[(2R,3R)-2,3-dihydroxy-2-methylbutanoate] 15-[(2R)-2-methylbutanoate], (3β,4α,6α,7α,15α,16β)- 124-97-0 C41H63NO15 Miscellaneous Natural Products