ChemicalBook > Product Catalog >Biochemical Engineering >Nucleoside drugs >Deoxynucleotides and their analogs >5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine

CAS No.: 104375-88-4

Chemical Name:: 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine

Synonyms: DMT-5-I-dU;5'-O-DMT-5-I-2'-dU;DMT-5-I-2'-deoxyuridine;5'-DMT-5-I-2'-deoxyuridine;5'-DMT-5-iodo-deoxyuridine;2'-Deoxy-5'-O-DMT-5-iodouridine;5'-O-DMT-5-iodo-2'-deoxyuridine;5'-O-DMT-5-iodo-2'-deoxyuridine;2'-Deoxy-5'-O-DMT-5-iodouridine;5'-O-DMTr-5-Iodo-2'-deoxyuridine

CBNumber:: CB0426433

Molecular Formula:: C30H29IN2O7

Molecular Weight:: 656.46

MOL File:: 104375-88-4.mol

MSDS File:: SDS

Modify Date:: 2024/2/23 10:06:30

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5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Properties

Melting point	>128 °C (decomp)
Density	1.60±0.1 g/cm3(Predicted)
pka	7.94±0.10(Predicted)
InChIKey	RLDUYGSOCGOJTP-SKDNVIITNA-N
SMILES	C(OC[C@@H]1[C@@H](O)C[C@H](N2C=C(C(=O)NC2=O)I)O1)(C1C=CC=CC=1)(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1 \|&1:3,4,7,r\|

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Chemical Properties,Uses,Production

Description

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine (2'-Deoxy-5'-O-DMT-5-iodouridine) is an intercalating agent that binds to DNA and RNA. It can be used as a probe for the detection of specific sequences in human cells. The fluorophore attached to the molecule allows it to be detected by fluorescence microscopy, while the chromophore is responsible for its ability to emit light at a wavelength of 535 nm. 2'-Deoxy-5'-O-DMT-5-iodouridine has been shown to enhance nucleotide excision repair and increase the sensitivity of cancer cells to chemotherapy drugs such as cisplatin. The molecule can also be used as a fluorescent protein marker in her-2 gene amplification and overexpression studies.

Uses

2’-Deoxy-5’-O-DMT-5-iodouridine is a modified oligonucleotides designed for use in genetic analysis and RNA detection.

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Preparation Products And Raw materials

Raw materials

Preparation Products

5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Suppliers

Global( 69)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	China	10311	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	China	5738	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	24200	58	Inquiry
Finetech Industry Limited	+86-27-87465837 +8618971612321	China	9640	58	Inquiry
BOC Sciences	16314854226; +16314854226	United States	19743	58	Inquiry
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	China	9980	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	China	25363	58	Inquiry
Wuhu Nuowei chemistry Co., Ltd.	+86-0553-2911116-802 +undefined17756524438	China	1640	58	Inquiry
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	+8618829768577	China	1250	58	Inquiry

Supplier	Advantage
Shenzhen Nexconn Pharmatechs Ltd	58
Chongqing Chemdad Co., Ltd	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
Dideu Industries Group Limited	58
Finetech Industry Limited	58
BOC Sciences	58
NewCan Biotech Limited	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Wuhu Nuowei chemistry Co., Ltd.	58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	58

104375-88-4(5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine)Related Search:

Uridine Pyrazine 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine N-blocked-5'-O-DMT 3'-CED iododeoxyuridine phosphoramidite 5-IODO-2',3'-DIDEOXYURIDINE

1-(2-HYDROXY-ETHOXYMETHYL)-5-IODO-1H-PYRIMIDINE-2,4-DIONE Idoxuridine 5'-O-(DIMETHOXYTRITYL)-5-IODO-2'-O-METHYLURIDINE

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5'-O-(DIMETHOXYTRITYL)-5-IODO-2'-DEOXYURIDINE 5''-O-(DIMETHOXYTRITYL)-5-IODO-2''-DEOXYURIDINE 99% 5'-DMT-5-iodo-deoxyuridine 2'-Deoxy-5'-O-DMT-5-iodouridine DMT-5-I-dU 5'-O-DMTr-5-Iodo-2'-deoxyuridine 5-Iodo-5'-diMethoxytrityl-2'-deoxyuridine 5'-O-(4,4'-Dimethoxytrityl)-5-Iodo-2'-deoxyuridine 5'-(4,4'-Dimethoxytrityl)-5-iodo-2'-deoxyuridine 5'-DMT-5-I-2'-deoxyuridine DMT-5-I-2'-deoxyuridine 5'-O-DMT-5-iodo-2'-deoxyuridine 5-Iodo-5'-O-(4, 4'-dimethoxytrityl)-2'-deoxyuridine Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-iodo- 5'-O-(DIMETHOXYTRITYL)-5-IODO-2'-DEOXYURIDINE USP/EP/BP 1-((2R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-iodouridine 1-[(2R,4S,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-hydroxyoxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine 5’-O-DMTr-5-iodo-2’-deoxyuridine 5-Iodo-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine 5'-O-DMT-5-I-2'-dU 5'-O-DMT-5-iodo-2'-deoxyuridine 2'-Deoxy-5'-O-DMT-5-iodouridine 104375-88-4 C30H29IN2O7