5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine
![5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Structure](CAS/GIF/104375-88-4.gif)
- CAS No.
- 104375-88-4
- Chemical Name:
- 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine
- Synonyms
- DMT-5-I-dU;5'-O-DMT-5-I-2'-dU;DMT-5-I-2'-deoxyuridine;5'-DMT-5-I-2'-deoxyuridine;5'-DMT-5-iodo-deoxyuridine;2'-Deoxy-5'-O-DMT-5-iodouridine;5'-O-DMT-5-iodo-2'-deoxyuridine;5'-O-DMT-5-iodo-2'-deoxyuridine;2'-Deoxy-5'-O-DMT-5-iodouridine;5'-O-DMTr-5-Iodo-2'-deoxyuridine
- CBNumber:
- CB0426433
- Molecular Formula:
- C30H29IN2O7
- Molecular Weight:
- 656.46
- MOL File:
- 104375-88-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/2/23 10:06:30
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Chemical Properties,Uses,Production
Description
5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine (2'-Deoxy-5'-O-DMT-5-iodouridine) is an intercalating agent that binds to DNA and RNA. It can be used as a probe for the detection of specific sequences in human cells. The fluorophore attached to the molecule allows it to be detected by fluorescence microscopy, while the chromophore is responsible for its ability to emit light at a wavelength of 535 nm. 2'-Deoxy-5'-O-DMT-5-iodouridine has been shown to enhance nucleotide excision repair and increase the sensitivity of cancer cells to chemotherapy drugs such as cisplatin. The molecule can also be used as a fluorescent protein marker in her-2 gene amplification and overexpression studies.
Uses
2’-Deoxy-5’-O-DMT-5-iodouridine is a modified oligonucleotides designed for use in genetic analysis and RNA detection.
5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Preparation Products And Raw materials
Raw materials
Preparation Products
5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10311 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24200 | 58 | Inquiry |
Finetech Industry Limited | +86-27-87465837 +8618971612321 | China | 9640 | 58 | Inquiry |
BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | China | 9980 | 58 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | China | 25363 | 58 | Inquiry |
Wuhu Nuowei chemistry Co., Ltd. | +86-0553-2911116-802 +undefined17756524438 | China | 1640 | 58 | Inquiry |
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8618829768577 | China | 1250 | 58 | Inquiry |