3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE
- CAS No.
- 1005-24-9
- Chemical Name:
- 3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE
- Synonyms
- 1-METHYLNICOTINAMIDE CHLORIDE;TRIA-662;Trionellamide chloride;TRIGONELLAMIDE CHLORIDE;nicotinamidemethochloride;nipecotamidemethochloride;Nicotinamide Impurity 127;nicotinamidemethylchloride;NICOTINAMIDE CHLOROMETHYLATE;n-methylnicotinamidechloride
- CBNumber:
- CB0431956
- Molecular Formula:
- C7H9ClN2O
- Molecular Weight:
- 172.61
- MOL File:
- 1005-24-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/25 20:04:51
| Melting point | 207-209℃ (water acetone ) |
|---|---|
| storage temp. | room temp |
| solubility | H2O: soluble15mg/mL, clear |
| form | crystalline |
| color | white |
| Water Solubility | almost transparency |
| Merck | 14,9693 |
| CAS DataBase Reference | 1005-24-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UU1925000 | |||||||||
| HS Code | 2933.39.9200 | |||||||||
| NFPA 704 |
|
3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0704 | 1-Methylnicotinamide chloride ≥98% (HPLC) | 1005-24-9 | 10MG | ₹4232.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0704 | 1-Methylnicotinamide chloride ≥98% (HPLC) | 1005-24-9 | 50MG | ₹12946.7 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M4627 | 1-Methylnicotinamide chloride analytical standard | 1005-24-9 | 1G | ₹16702.98 | 2022-06-14 | Buy |
| TCI Chemicals (India) | M0375 | 3-Carbamyl-1-methylpyridinium Chloride | 1005-24-9 | 5G | ₹5200 | 2022-05-26 | Buy |
| TCI Chemicals (India) | M0375 | 3-Carbamyl-1-methylpyridinium Chloride | 1005-24-9 | 25G | ₹18800 | 2022-05-26 | Buy |
3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE Chemical Properties,Uses,Production
Description
Nicotinamide is a precursor of NAD and NADP , which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced by the action of nicotinamide N-methyltransferase (NNMT; ). It demonstrates antithrombotic and anti-inflammatory properties through direct action on the endothelium by a mechanism involving the prostacyclin pathway and by improving nitric oxide bioavailability. Aggressive cancer cell lines are reported to have higher levels of MNA due to increased NNMT-directed transfer of methyl groups from S-adenosyl-L-methionine to nicotinamide, implicating a role for MNA in cancer cell metabolism.
Uses
Nicotinamide is a precursor of NAD and NADP , which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced by the action of nicotinamide N-methyltransferase (NNMT; ). It demonstrates antithrombotic and anti-inflammatory properties through direct action on the endothelium by a mechanism involving the prostacyclin pathway and by improving nitric oxide bioavailability. Aggressive cancer cell lines are reported to have higher levels of MNA due to increased NNMT-directed transfer of methyl groups from S-adenosyl-L-methionine to nicotinamide, implicating a role for MNA in cancer cell metabolism.
General Description
1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced mainly by nicotinamide N-methyltransferase (NNMT) and exhibits antithrombotic and anti-inflammatory effects.
Purification Methods
Recrystallise it from MeOH. [Beilstein 22 III/IV 468, 22/2 V 80.]
3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Anthem Biosciences Pvt Ltd | +91-8066724000 +91-9900044575 | Karnataka, India | 38 | 58 | Inquiry |
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| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | China | 2063 | 58 | Inquiry |
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