N-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDE

N-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDE Structure
CAS No.
673-50-7
Chemical Name:
N-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDE
Synonyms
methylhistamine;n’-methylhistamine;Na-Methylhistamine2HCl;n(supalpha)-methylhistamine;4-(2-methylaminoethyl)imidazole;4-(2-(methylamino)ethyl)-imidazol;n-methyl-1h-imidazole-4-ethanamin;N-Methyl-1H-imidazole-4-ethanamine;NA-METHYLHISTAMINE DIHYDROCHLORIDE;IMIDAZOLE,4-(2-(METHYLAMINO)ETHYL)-
CBNumber:
CB0432014
Molecular Formula:
C6H11N3
Molecular Weight:
125.17
MOL File:
673-50-7.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:41

N-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDE Properties

Melting point 188-189 °C
Boiling point 309.1±17.0 °C(Predicted)
Density 1.050±0.06 g/cm3(Predicted)
storage temp. Store at RT
pka 14.58±0.10(Predicted)

N-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDE Chemical Properties,Uses,Production

Uses

2-(1H-Imidazol-5-yl)-N-methylethanamine is a metabolite of histamine.

Synthesis Reference(s)

Tetrahedron, 23, p. 239, 1967 DOI: 10.1016/S0040-4020(01)83305-6

Biological Activity

Potent histamine agonist, particularly at H 3 receptors (potency relative to histamine is 81, 185, and 270% at H 1 , H 2 and H 3 respectively). Also displays agonist properties at H 4 receptors to which it binds with moderate affinity (K i = 23 nM).

N-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

N-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDE Suppliers

Global( 13)Suppliers
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Hefei TNJ Chemical Industry Co.,Ltd. +86-0551-65418671 +8618949823763 China 34571 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Hangzhou J&H Chemical Co., Ltd. 0571-+86-571-87396432 China 11425 59 Inquiry
EMD Biosciences, Inc. 858 450 5500 United States 6529 66 Inquiry
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Tocris Bioscience +44 (0) 117 916 3333 United Kingdom 5729 77 Inquiry
4-(2-methylaminoethyl)imidazole 4-(2-(methylamino)ethyl)-imidazol methylhistamine n(supalpha)-methylhistamine n’-methylhistamine n-methyl-1h-imidazole-4-ethanamin IMIDAZOLE,4-(2-(METHYLAMINO)ETHYL)- NA-METHYLHISTAMINE DIHYDROCHLORIDE Methylhistamine dihydrochloride Nalpha- N-Methyl-1H-imidazole-4-ethanamine 2-(1H-imidazol-5-yl)ethyl-methyl-amine 2-(1H-imidazol-5-yl)-N-methylethanamine 2-(1H-imidazol-5-yl)-N-methyl-ethanamine N-ALPHA-METHYLHISTAMINE DIHYDROCHLORIDE N-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDE Na-Methylhistamine2HCl 1H-Imidazole-5-ethanamine, N-methyl- 673-50-7 C6H13Cl2N3 Histamine receptor