Cortistatin-29 (rat) (trifluoroacetate salt)

Cortistatin-29 (rat) (trifluoroacetate salt) Structure
CAS No.
1815618-17-7
Chemical Name:
Cortistatin-29 (rat) (trifluoroacetate salt)
Synonyms
Cortistatin-29 (rat) (H-6444.0500);Cortistatin-29 (rat) (trifluoroacetate salt);L-Lysine, 5-oxo-L-prolyl-L-α-glutamyl-L-arginyl-L-prolyl-L-prolyl-L-leucyl-L-glutaminyl-L-glutaminyl-L-prolyl-L-prolyl-L-histidyl-L-arginyl-L-α-aspartyl-L-lysyl-L-lysyl-L-prolyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-seryl-L-s...
CBNumber:
CB04665931
Molecular Formula:
C161H240N46O41S2
Molecular Weight:
3540.04
MOL File:
1815618-17-7.mol
Modify Date:
2024/3/27 11:49:37

Cortistatin-29 (rat) (trifluoroacetate salt) Properties

Density 1.54±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Water: 1 mg/ml
form A lyophilized powder
Sequence Pyr-Glu-Arg-Pro-Pro-Leu-Gln-Gln-Pro-Pro-His-Arg-Asp-Lys-Lys-Pro-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH (Disulfide bonds)

Cortistatin-29 (rat) (trifluoroacetate salt) Chemical Properties,Uses,Production

Description

Cortistatin-29 is a neuropeptide that is structurally similar to somatostatin-28. It is produced by cleavage of preprocortistatin to procortistatin, which is cleaved at dibasic amino acids to form cortistatin-29 and cortistatin-14 as well as other partial cleavage products. Cortistatin mRNA is expressed in the human brain and in interneurons of the rat hippocampus and cerebral cortex. Cortistatin-29 binds to somatostatin (SST) receptors with IC50 values of 2.8, 7.1, 0.2, 3, and 13.7 nM for SST1-5, respectively. Cortistatin-29 is found at similar levels as cortistatin-14 in mouse AtT20 cells but is secreted at a lower level. Cortistatin-29 corresponds to residues 85-112 of the rat peptide sequence.

Cortistatin-29 (rat) (trifluoroacetate salt) Preparation Products And Raw materials

Raw materials

Preparation Products

Cortistatin-29 (rat) (trifluoroacetate salt) Suppliers

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1815618-17-7(Cortistatin-29 (rat) (trifluoroacetate salt))Related Search:

Cortistatin-29 (rat) (trifluoroacetate salt) Cortistatin-29 (rat) (H-6444.0500) L-Lysine, 5-oxo-L-prolyl-L-α-glutamyl-L-arginyl-L-prolyl-L-prolyl-L-leucyl-L-glutaminyl-L-glutaminyl-L-prolyl-L-prolyl-L-histidyl-L-arginyl-L-α-aspartyl-L-lysyl-L-lysyl-L-prolyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-seryl-L-s... 1815618-17-7