CARBACYCLIN

CARBACYCLIN Structure
CAS No.
69552-46-1
Chemical Name:
CARBACYCLIN
Synonyms
CPGI;Carba pgx;Carba-PGI2;CARBACYCLIN;Carbacycline;6A-Carba-pgi2;6,9-Methano-pgi2;6,9-Methano pgi2;CARBACYCLIC PGI2;CARBOCYCLIC PGI2
CBNumber:
CB0475042
Molecular Formula:
C21H34O4
Molecular Weight:
350.49
MOL File:
69552-46-1.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:54:58

CARBACYCLIN Properties

Melting point 65-67℃
Boiling point 514.8±50.0 °C(Predicted)
Density 1.177±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility Soluble at 20mg/ml in ethanol.
form Solid
pka 4.77±0.10(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P261-P280h-P301+P312a-P304+P340-P321-P501a
Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  22-36
WGK Germany  3
NFPA 704
3
2 0

CARBACYCLIN Chemical Properties,Uses,Production

Uses

Carbacyclin is a stable analog of PGI2. When infused in rabbits or dogs, it inhibits ex vivo platelet aggregation, but the effect persists only 10 minutes after termination of the infusion. Carbacyclin is a stable analog of PGI2. Carbacyclin inhibits platelet aggregation with 10% of the molar potency exhibited by PGI2. The ED50 of Carbacyclin for the in vitro inhibition of ADP-induced platelet aggregation in human PRP is 47 nM. It was also shown to effect terminal differentiation of preadipose into adipose cells and enhance the expression of angiotensinogen and adipose fatty acid binding protein with an EC50 of about 0.5 μM.

CARBACYCLIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 33)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
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6,9ALPHA-METHYLENE-11ALPHA,15S-DIHYDROXY-PROSTA-5E,13E-DIEN-1-OIC ACID 6A-CARBA-PROSTAGLANDIN I2 carboprostacyclin 6,9-Methanoprostaglandin I2 6a-Carba-prostaglandinI2, CarbocyclicPGI2 (5E)-6a-Carbaprostaglandin 12 5-[(1β,3E,5β,6R)-6β-[(1E,3S)-3-Hydroxy-1-octenyl]-7α-hydroxybicyclo[3.3.0]octane-3-ylidene]pentanoic acid 5-[(2E,3aS,5R,6aβ)-Octahydro-5α-hydroxy-4β-[(1E,3S)-3-hydroxy-1-octenyl]pentalen-2-ylidene]pentanoic acid (5E)-6A-Carba-prostaglandin I2 6,9-Methano pgi2 6,9-Methano-pgi2 6A-Carba-pgi2 9alpha-Deoxy-9alpha-methylene-pgi2 Carba pgx Carbacycline Carbacyclin (Carbocyclic PGI2) CARBACYCLIC PGI2 CARBACYCLIN CARBAPROSTACYCLIN CARBOCYCLIC PGI2 CARBOCYCLIC PGL2 CPGI Pentanoic acid,5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-1-octenyl]-2(1H)-pentalenylidene]-,(5E)- Carba-PGI2 Carbacyclin (Carbocyclic PGI?) 69552-46-1 BioChemical Biochemicals and Reagents Prostaglandins Lipids Fatty Acids