ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Glycine derivative >DL-THIORPHAN
DL-THIORPHAN
- CAS No.
- 76721-89-6
- Chemical Name:
- DL-THIORPHAN
- Synonyms
- C01619;THIORPHAN;Thiorphan-d5;DL-THIORPHAN;THIORPHAN (DL);DL-THIORPHAN USP/EP/BP;Bisoprolol FuMarate IMpurity-Q;(DL-3-MERCAPTO-2-BENZYLPROPANOYL)-GLY;(2-benzyl-3-mercaptopropanoyl)glycine;DL-3-MERCAPTO-2-BENZYLPROPANOYL-GLYCINE
- CBNumber:
- CB0479626
- Molecular Formula:
- C12H15NO3S
- Molecular Weight:
- 253.32
- MOL File:
- 76721-89-6.mol
- Modify Date:
- 2023/5/4 17:34:42
| Melting point | 138-140 °C |
|---|---|
| Boiling point | 524.0±50.0 °C(Predicted) |
| Density | 1.246±0.06 g/cm3(Predicted) |
| RTECS | MC0596440 |
| storage temp. | -15°C |
| solubility | ethanol: 50 mg/mL, clear, colorless |
| form | White solid |
| pka | 3.48±0.10(Predicted) |
| color | White to Off-White |
| BRN | 4872101 |
| CAS DataBase Reference | 76721-89-6 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| F | 10 |
| HS Code | 29309090 |
DL-THIORPHAN price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T6031 | DL-Thiorphan ≥98% (TLC) | 76721-89-6 | 5MG | ₹17991.15 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T6031 | DL-Thiorphan ≥98% (TLC) | 76721-89-6 | 25MG | ₹71369.23 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 598510 | DL-Thiorphan - CAS 76721-89-6 - Calbiochem A thiol containing amido-acid that selectively binds to the active site zinc of metalloproteinases and blocks their activity (IC?? = 2.1 nM for neutra | 76721-89-6 | 10MG | ₹39430 | 2022-06-14 | Buy |
DL-THIORPHAN Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
DL-Thiorphan has been used to evaluate the activity of NEP-dependent neutral endopeptidase. DL-Thiorphan has also been used for determining NEP enzymatic activity using fluorimetric assays.
General Description
A thiol-containing amido-acid that selectively binds to the active site zinc of neprilysin (also known as neutral endopeptidase and NEP) and inhibits its activity (IC50 = 2.1 nM). Inhibits the β-amyloid (Aβ) degrading activity of neprilysin in vivo, but does not affect the secretion of either Aβ peptide or amyloid precursor protein (APP). Also shown to inhibit other neprilysin-related family members, such as mouse NL1 (IC50 = 47 nM) and the neprilysin homolog from Ascaris suum (IC50 = 22 μM). Inhibits the activity of angiotensin-converting enzyme (ACE) (IC50 = 140 nM), but has no effect on the activity of endothelin-converting enzyme (ECE).
DL-THIORPHAN Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 117)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Varanous Labs Pvt Ltd | +91-7036248882 +91-7036248882 | Hyderabad, India | 1541 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | China | 30255 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26823 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | China | 19915 | 58 | Inquiry |
76721-89-6(DL-THIORPHAN)Related Search:
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Benzyl glycinate p-toluenesulfonate
ACETYL SULFIDE
Thiorphan Disulfide
Diethyl benzylmalonate
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N-[(RS)-2-BENZYL-3-MERCAPTOPROPANOYL]-GLYCINE
(+/-)-N-(3-MERCAPTO-2-BENZYLPROPIONYL)GLYCINE
N-ALPHA-(DL-3-MERCAPTO-2-BENZYLPROPANOYL)-GLYCINE
THIORPHAN
THIORPHAN (DL)
((RS)-2-BENZYL-3-MERCAPTOPROPIONYL)-GLYCINE
((RS)-2-BENZYL-3-MERCAPTOPROPIONYL)-GLY-OH
2-Mercaptomethyl-3-phenyl-propionylamino-acetic Acid, D,L-3-Mercapto-2-benzylpropanoylglycine,
(±)-N-(3-Mercapto-2-benzylpropionyl)glycine, DL-3-Mercapto-2-benzylpropanoylglycine
rac-N-[(2R*)-3-Mercapto-2-benzylpropionyl]glycine
C01619
2-MercaptoMethyl-3-phenylpropionylaMinoacetic Acid
N-[2-(MercaptoMethyl)-1-oxo-3-phenylpropyl]glycine
2-[[2-(Benzyl)-3-sulfanylpropanoyl]aMino]acetic acid
2-(2-benzyl-3-MercaptopropanaMido)acetic acid
(DL-3-Mercapto-2-benzylpropionyl)-Gly-OH, (DL-3-Mercapto-2-benzylpropanoyl)-Gly-OH
Bisoprolol FuMarate IMpurity-Q
Thiorphan-d5
(DL-3-MERCAPTO-2-BENZYLPROPANOYL)-GLY
DL-3-MERCAPTO-2-BENZYLPROPANOYL-GLYCINE
(DL-3-MERCAPTO-2-BENZYLPROPANOYL)-GLY-OH
DL-THIORPHAN
DL-Thiorphan - CAS 76721-89-6 - Calbiochem
Racecadotril Impurity 2（Racecadotril EP Impurity B）
2-(2-benzyl-3-sulfanylpropanamido)acetic acid
Racecadotril impurity 1/Racecadotril EP impurity B/Thiorphan/[[(2RS)-2-benzyl-3-sulfanylpropanoyl]amino]acetic acid
Glycine, N-[2-(mercaptomethyl)-1-oxo-3-phenylpropyl]-
2-[(2-benzyl-3-sulfanylpropanoyl)amino]aceticaci
DL-THIORPHAN USP/EP/BP
(2-benzyl-3-mercaptopropanoyl)glycine
[[(2RS)-2-benzyl-3-sulfanylpropanoyl]amino]acetic acid
76721-89-6
25332
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