Sildenafil Impurity 18

Sildenafil Impurity 18 Structure
CAS No.
2196244-90-1
Chemical Name:
Sildenafil Impurity 18
Synonyms
SildefilImpurity18;Sildenafil Impurity 71;Dithiopropylcarbodenafil;Sildenafil Impurity 155(Dithiopropylcarbodenafil);Sildenafil Impurity 18 (Dithiopropylcarbodenafil);Carbodenafil Impurity 3(Dithiopropylcarbodenafil);7H-Pyrazolo[4,3-d]pyrimidine-7-thione, 5-[2-ethoxy-5-[(4-propyl-1-piperazinyl)thioxomethyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-
CBNumber:
CB04820932
Molecular Formula:
C25H34N6OS2
Molecular Weight:
498.71
MOL File:
2196244-90-1.mol
Modify Date:
2023/5/15 10:43:54

Sildenafil Impurity 18 Properties

Boiling point 656.9±65.0 °C(Predicted)
Density 1.28±0.1 g/cm3(Predicted)
solubility Chloroform (Slightly), Methanol (Slightly)
pka 7.58±0.10(Predicted)
form Solid
color Pale Beige to Pale Brown

Sildenafil Impurity 18 Chemical Properties,Uses,Production

Uses

5-[2-ethoxy-5-[(4-propyl-1-piperazinyl)thioxomethyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-Pyrazolo[4,3-d]pyrimidine-7-thione, also known as Dithiopropylcarbodenafil, is an impurity of Sildenafil (S435001), an orally active selective type 5 cGMP phosphodiesterase inhibitor. Dithiopropylcarbodenafil was first reported by Yun et al. in 2018.

Sildenafil Impurity 18 Preparation Products And Raw materials

Raw materials

Preparation Products

Carbodenafil Impurity 3(Dithiopropylcarbodenafil) Sildenafil Impurity 18 (Dithiopropylcarbodenafil) Sildenafil Impurity 71 Dithiopropylcarbodenafil Sildenafil Impurity 155(Dithiopropylcarbodenafil) SildefilImpurity18 7H-Pyrazolo[4,3-d]pyrimidine-7-thione, 5-[2-ethoxy-5-[(4-propyl-1-piperazinyl)thioxomethyl]phenyl]-1,6-dihydro-1-methyl-3-propyl- 2196244-90-1