ACEA

ACEA Structure
CAS No.
273734-07-9
Chemical Name:
ACEA
Synonyms
ACEA;2'-CHLORO-AEA;ARACHIDONYL-2-CHLOROETHYLAMIDE;ARACHIDONYL-2'-CHLOROETHYLAMIDE;ARACHIDONOYL 2'-CHLOROETHYLAMIDE;N-(2-CHLOROETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;Propanamide, 3-chloro-N-(4Z,7Z,10Z,13Z)-4,7,10,13-nonadecatetraen-1-yl-
CBNumber:
CB0484073
Molecular Formula:
C22H36ClNO
Molecular Weight:
365.98
MOL File:
273734-07-9.mol
Modify Date:
2023/5/4 17:34:37

ACEA Properties

storage temp. −20°C
solubility DMSO: soluble
form oil
color pale yellow

SAFETY

Risk and Safety Statements

WGK Germany  3

ACEA Chemical Properties,Uses,Production

Enzyme inhibitor

This synthetic CB1 receptor agonist and anandamide (N- arachidonylethanolamide) analogue (FW = 365.99 g/mol; CAS 220556-69- 4; Symbol: ACEA) is a selective agonist of cannabinoid receptor-1 (Ki = 1.4 nM) but has low affinity to the cannabinoid receptor 2 (Ki = 3.1 μM). ACEA inhibits forskolin-induced cAMP accumulation in Chinese hamster ovary cells expressing the human CB1 receptor. It also increases the binding of [35S]GTPgS to cerebellar membranes and inhibits electrically evoked contractions of the mouse vas deferens. ACEA produces hypothermia in mice, an effect that is inhibited by co-administration of the CB1 receptor antagonist SR141716A.

ACEA Preparation Products And Raw materials

Raw materials

Preparation Products

ACEA Suppliers

Global( 14)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
BIOMOL INTERNATIONAL, LP (800) 942-0430 United States 1503 77 Inquiry
Alexis Corporation +41 61 926 8989 Switzerland 3599 74 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
EMD Biosciences, Inc. 858 450 5500 United States 6529 66 Inquiry
VWR International 800 932 5000 United Kingdom 6554 82 Inquiry
Tocris Bioscience +44 (0) 117 916 3333 United Kingdom 5729 77 Inquiry
SIGMA-RBI 800 736 3690 (Orders) Switzerland 6913 91 Inquiry
Service Chemical Inc. 888-895-6920 Germany 6373 71 Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 China 15848 69 Inquiry
Sigma-Aldrich 021-61415566 800-8193336 China 51471 80 Inquiry

273734-07-9(ACEA)Related Search:

ARACHIDONYL-2'-CHLOROETHYLAMIDE ARACHIDONYL-2-CHLOROETHYLAMIDE ARACHIDONOYL 2'-CHLOROETHYLAMIDE N-(2-CHLOROETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE ACEA 2'-CHLORO-AEA Propanamide, 3-chloro-N-(4Z,7Z,10Z,13Z)-4,7,10,13-nonadecatetraen-1-yl- 273734-07-9