LIPOXIN A4

LIPOXIN A4 Structure
CAS No.
89663-86-5
Chemical Name:
LIPOXIN A4
Synonyms
LXA;LXA4;LIPOXIN A;LIPOXIN A4;LXA4, CID5280914;5(S),6(R)-LIPOXIN A4;5(S),6(R),15(S)-TRIHETE;Lipoxin A4 MaxSpecStandard;IXAQOQZEOGMIQS-SSQFXEBMSA-N;Lipoxin A - CAS 89663-86-5 - Calbiochem
CBNumber:
CB0687274
Molecular Formula:
C20H32O5
Molecular Weight:
352.47
MOL File:
89663-86-5.mol
Modify Date:
2024/7/2 8:54:58

LIPOXIN A4 Properties

Boiling point 589.4±50.0 °C(Predicted)
Density 1.096±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility A solution in ethanol, can isomerize and degrade when put into freeze thaw conditions or in solvents such as DMSO, or DMF, 50 mg/ml in Ethanol, 1 mg/ml in PBS (pH 7.2)
form ethanol solution
pka 4.67±0.10(Predicted)
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P305+P351+P338
Hazard Codes  F
Risk Statements  11
Safety Statements  7-16
RIDADR  UN 1170 3/PG 2
WGK Germany  1
NFPA 704
3
2 0

LIPOXIN A4 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) L0521 Lipoxin A4 ethanol solution 89663-86-5 25μG ₹80544.8 2022-06-14 Buy
Sigma-Aldrich(India) 437720 Lipoxin A₄ - CAS 89663-86-5 - Calbiochem Lipoxin A?, CAS 89663-86-5, is a potent inhibitor of cytotoxic activity of human natural killer cells. Shown to be as potent as LTB4 in stimulating hu 89663-86-5 25μG ₹37770 2022-06-14 Buy
Product number Packaging Price Buy
L0521 25μG ₹80544.8 Buy
437720 25μG ₹37770 Buy

LIPOXIN A4 Chemical Properties,Uses,Production

Uses

Lipoxin A4 (LXA4) is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of (±)15-HETE or 15-HpETE with human leukocytes. LXA4 is equipotent to leukotriene B4 in inducing superoxide generation in human neutrophils at 0.1 μM. LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural killer cell inhibition, and monocyte migration and adhesion. Analytical and biological comparisons of synthetic LXA4 with endogenously derived LXA4 have confirmed its identity as matching the natural product.

Definition

ChEBI: A C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-doubl bonds.

General Description

Caution! Product contains volatile liquid. Keep product cold at all times.

LIPOXIN A4 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 45)Suppliers
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SIGMA-RBI 800 736 3690 (Orders) Switzerland 6913 91 Inquiry
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Shanghai Hao Biological Technology Co., Ltd. 021-80370006 13585899102 CHINA 6805 58 Inquiry
Beijing Taize Ruida Technology Co., Ltd. 400-800-8151 13651185998 CHINA 6536 58 Inquiry
LIPOXIN A LIPOXIN A4 LXA LXA4 5(S),6(R),15(S)-TRIHETE [5S,6R,15S]-TRIHYDROXY-[7E,9E,11Z,13E]-EICOSATETRAENOIC ACID 5(S),6(R),15(S)-TRIHYDROXYEICOSA-7E,9E,11Z,13E-TETRAENOIC ACID 5(S), 6(R), 15(S)-TRIHYDROXYEICOSA-7-TRANS-9-TRANS-11-CIS-13-TRANS-TETRAENOIC ACID 5(S),6(R)-LIPOXIN A4 (5S,6R,7E,9E,11Z,13E,15S)-5,6,15-trihydroxyicosa-7,9,11,13-tetraenoic acid (5S,6R,7E,9E,11Z,13E,15S)-5,6,15-Trihydroxy-7,9,11,13-icosatetraenoic acid 5(S),6(R)-Lipoxin A4 Lipid Maps MS Standard LXA4, CID5280914 IXAQOQZEOGMIQS-SSQFXEBMSA-N Lipoxin A4 MaxSpecStandard Lipoxin A - CAS 89663-86-5 - Calbiochem 7,9,11,13-Eicosatetraenoic acid, 5,6,15-trihydroxy-, (5S,6R,7E,9E,11Z,13E,15S)- 5,6,15-Trihydroxyicosa-7,9,11,13-tetraenoic acid 89663-86-5 BioChemical Cell Biology Cell Signaling and Neuroscience Protein Kinase C (PKC) Kinase/Phosphatase Biology Serine/Threonine Kinase Activators