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15(S)-HETE

15(S)-HETE Structure
CAS No.
54845-95-3
Chemical Name:
15(S)-HETE
Synonyms
C04742;AL12959;AL 12959;AL-12959;Icomucret;15(S)-HETE;(S)-15-HETE;JSFATNQSLKRBCI-VAEKSGALSA-N;15(S)-HETE MaxSpec Standard;15(S)-HETE Lipid Maps MS Standard
CBNumber:
CB0724870
Molecular Formula:
C20H32O3
Molecular Weight:
320.47
MOL File:
54845-95-3.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:03:04

15(S)-HETE Properties

Boiling point 487.7±45.0 °C(Predicted)
Density 0.984±0.06 g/cm3(Predicted)
Flash point 14℃
storage temp. -20°C
solubility 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): 0.8 mg/ml
form Liquid.
pka 4.75±0.10(Predicted)
BRN 2470466

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H315-H319-H335
Precautionary statements  P210-P261-P305+P351+P338
Hazard Codes  F,Xi
Risk Statements  11-36/37/38
Safety Statements  7-16-26-36
RIDADR  UN 1170 3/PG 2
WGK Germany  3
NFPA 704
3
0 0

15(S)-HETE Chemical Properties,Uses,Production

Uses

15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes. 15(S)-HETE is present in μg/ml concentrations in the nasal secretions of allergic rhinitis.

Definition

ChEBI: An optically active form of 15-HETE having 15(S)-configuration..

General Description

15(S)-HETE is a product of the arachidonic acid pathway. It is synthesized by the human lungs and airway epithelial cells. 15(S)-HETE is a potent mucosecretagogue in human airways. It is a metabolite of 15-lipoxygenase. 15(S)-HETE is an endogenous ligand for peroxisome proliferator-activated receptor γ (PPARγ).

15(S)-HETE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 48)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
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Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9707 58 Inquiry
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 China 4428 55 Inquiry
Taizhou Nanfeng Pharmaceutical Research Institute 18616377689 China 20566 58 Inquiry
SHANGHAI ZZBIO CO., LTD. 13916577892 19921389125 China 12063 58 Inquiry
Guangdong Wengjiang Chemical Reagent Co.,Ltd. 0751-2815983 13927872582 China 2529 58 Inquiry
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 China 8141 58 Inquiry
C04742 15(S)-HETE Lipid Maps MS Standard (S)-15-HETE 15(S)-HYDROXY-(5Z,8Z,11Z,13E)-EICOSATETRAENOIC ACID 15(S)-HYDROXYEICOSA-5Z,8Z,11Z,13E-TETRAENOIC ACID 15(S)-HETE (15s,5z,8z,11z,13e)-15-hydroxyeicosatetraenoic acid (5Z,8Z,11Z,13E,15S)-15-hydroxyicosa-5,8,11,13-tetraenoic acid Icomucret (5Z,8Z,11Z,13E,15S)-15-Hydroxy-5,8,11,13-icosatetraenoic acid (15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate (15S)-15-Hydroxy-5,8,11-cis-13-trans-icosatetraenoate JSFATNQSLKRBCI-VAEKSGALSA-N 15(S)-HETE MaxSpec Standard 5,8,11,13-Eicosatetraenoic acid, 15-hydroxy-, (5Z,8Z,11Z,13E,15S)- AL 12959 AL12959 AL-12959 54845-95-3 Polyunsaturated Unsaturated fatty acids and derivatives Biochemicals and Reagents BioChemical Fatty Acids Lipids Hydroxy fatty acids