Chinese english Japanese Germany Korea

6',7'-DIHYDROXYBERGAMOTTIN

6',7'-DIHYDROXYBERGAMOTTIN Structure
CAS No.
145414-76-2
Chemical Name:
6',7'-DIHYDROXYBERGAMOTTIN
Synonyms
6',7'-DIHYDROXYBERGAMOTTIN;6,7-dihydroxybergaMottin(DHB);4-[[(2E)-6,7-Dihydroxy-3,7-dimethyl-2-octen-1-yl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one;7H-Furo[3,2-g][1]benzopyran-7-one, 4-[[(2E)-6,7-dihydroxy-3,7-dimethyl-2-octen-1-yl]oxy]-
CBNumber:
CB0765541
Molecular Formula:
C21H24O6
Molecular Weight:
372.41
MOL File:
145414-76-2.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:06
Request For Quotation

6',7'-DIHYDROXYBERGAMOTTIN Properties

Melting point 112-113 °C
Boiling point 578.2±50.0 °C(Predicted)
Density 1.260
storage temp. 2-8°C
solubility ethanol: soluble
pka 14.65±0.29(Predicted)
form Solid
color white to off-white

SAFETY

Risk and Safety Statements

WGK Germany  3

6',7'-DIHYDROXYBERGAMOTTIN price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) UC441 6´,-7´-Dihydroxybergamottin 145414-76-2 5MG ₹78570 2022-06-14 Buy
Sigma-Aldrich(India) UC441 6´,-7´-Dihydroxybergamottin 145414-76-2 10MG ₹153097.98 2022-06-14 Buy
Product number Packaging Price Buy
UC441 5MG ₹78570 Buy
UC441 10MG ₹153097.98 Buy

6',7'-DIHYDROXYBERGAMOTTIN Chemical Properties,Uses,Production

Description

6,7-dihydroxy Bergamottin (6,7-DHB) is a potent inhibitor of CYP3A4 (IC50 = 25 μM). It appears to be the primary compound in grapefruit juice that is responsible for inhibition of testosterone 6β-hydrolase activity. Ingestion of grapefruit juice during treatment regimes with drugs normally metabolized by cytochrome P450 enzymes of the CYP3A subfamily results in a substantial increase in plasma concentration of these agents. However, giving a patient grapefruit juice or just 6,7-DHB could be advantageous in cases where a drug is metabolized too quickly by CYP3A4.

Uses

A minor metabolite of Bergamottin. Metabolization of Bergamottin by cytochromes P 450 2B6 and 3A5.

Biochem/physiol Actions

CYP3A4 inhibitor.

6',7'-DIHYDROXYBERGAMOTTIN Preparation Products And Raw materials

Raw materials

Preparation Products

6',7'-DIHYDROXYBERGAMOTTIN Suppliers

Global( 49)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29825 58 Inquiry
Wuhan Nutra Biotechnology Co.,Ltd +8617786394783 China 300 58 Inquiry
Wuhan Kemi-Works Chemical Co., Ltd. +86-2785736489 +8618171418573 China 726 58 Inquiry
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 China 11289 58 Inquiry
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 China 8141 58 Inquiry
NE Scientific +1 (617) 651-6662 United States 5031 55 Inquiry
Foshan Treasure Biotechnology Co., Ltd 0757-85921206 18520245316 China 12664 58 Inquiry
Chengdu Peter-like Biotechnology Co., Ltd. 028-81700200 18108052721 China 5178 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Supplier Advantage
Pharmaffiliates Analytics and Synthetics P. Ltd 58
career henan chemical co 58
Wuhan Nutra Biotechnology Co.,Ltd 58
Wuhan Kemi-Works Chemical Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
NE Scientific 55
Foshan Treasure Biotechnology Co., Ltd 58
Chengdu Peter-like Biotechnology Co., Ltd. 58
Cayman Chemical Company 81

145414-76-2(6',7'-DIHYDROXYBERGAMOTTIN)Related Search:

4-ALLYLOXYCOUMARIN 6',7'-DIHYDROXYBERGAMOTTIN 4-ETHOXYCOUMARIN 1-BENZOFURAN-5-YLMETHANOL
4-[[(2E)-6,7-Dihydroxy-3,7-dimethyl-2-octen-1-yl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one 6',7'-DIHYDROXYBERGAMOTTIN 6,7-dihydroxybergaMottin(DHB) 7H-Furo[3,2-g][1]benzopyran-7-one, 4-[[(2E)-6,7-dihydroxy-3,7-dimethyl-2-octen-1-yl]oxy]- 145414-76-2 Heterocycles Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Drug and Xenobiotic Metabolism Multi-Drug Resistance and Drug Metabolism Substrates, Inducers, Inhibitors