Molnupiravir
![Molnupiravir Structure](CAS/20210111/GIF/2492423-29-5.gif)
- CAS No.
- 2492423-29-5
- Chemical Name:
- Molnupiravir
- Synonyms
- Molnupiravir-001-QA;Molnupiravir In-House;Uridine, 4-oxime, 5'-(2-methylpropanoate), (4Z)-;Molnupiravir D7Q: What is Molnupiravir D7 Q: What is the CAS Number of Molnupiravir D7;[(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methyl 2-methylpropanoate;(2R,3S,4R,5R)-3,4-dihydroxy-5-[(4Z)-4-hydroxyimino-2-oxo-pyrimidin-1-yl]tetrahydrofuran-2-yl]methyl 2-methylpropanoate;((2R,3S,4R,5R)-3,4-Dihydroxy-5-((Z)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl isobutyrate;MolnupiravirQ: What is Molnupiravir Q: What is the CAS Number of Molnupiravir Q: What is the storage condition of Molnupiravir;((2R,3S,4R,5R)-3,4-Dihydroxy-5-((Z)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl isobutyrate (Molnupiravir Impurity)
- CBNumber:
- CB08369543
- Molecular Formula:
- C13H19N3O7
- Molecular Weight:
- 329.31
- MOL File:
- 2492423-29-5.mol
- Modify Date:
- 2024/7/2 8:54:58
Molnupiravir Chemical Properties,Uses,Production
Description
Prodrug of antiviral nucleoside analog; inhibits SARS-CoV, SARS-CoV-2 and MERS-CoV infection.
Biological Activity
Molnupiravir is a broad-spectrum antiviral prodrug of the nucleoside analog β-D-N4-hydroxycytidine (NHC). It competes predominantly with CTP for incorporation; it induces lethal viral mutagenesis by increasing G to A and C to U transition mutations without inhibition of RNA synthesis in replicating coronaviruses, which prevents the development of viral resistance. In primary airway epithelial cell cultures, Molnupiravir dose-dependently inhibits SARS-CoV-2 infectious virus production; it also inhibits MERS-CoV and SARS-CoV with EC50 values in the submicromolar range. In mice infected with SARS-CoV or MERS-CoV, it improves pulmonary function, and reduces virus titer and body weight loss. Molnupiravir also displays in vivo efficacy against seasonal and pandemic influenza A shed virus. It is orally bioavailable.
Molnupiravir Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Hangzhou Proserre Chemical Co.,Ltd. | +86-571-86088112 | China | 1077 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
Nanjing Shizhou Biotechnology Co., Ltd | +86-15850508050 +86-15850508050 | China | 323 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24330 | 58 | Inquiry |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | China | 8474 | 58 | Inquiry |