N(4)-hydroxycytidine
- CAS No.
- 3258-02-4
- Chemical Name:
- N(4)-hydroxycytidine
- Synonyms
- EIDD-1931;N-Hydroxycytidine;0/4/58;EIDD-193;Engagliflozin;Uridine, 4-oxime;Monovir impurity A;EIDD 2801-metabolit;EIDD2801-metabolite;N(4)-hydroxycytidine
- CBNumber:
- CB21312265
- Molecular Formula:
- C9H13N3O6
- Molecular Weight:
- 259.22
- MOL File:
- 3258-02-4.mol
- Modify Date:
- 2024/7/11 17:04:31
Melting point | 169-172 °C(Solv: methanol (67-56-1)) |
---|---|
Density | 1.93±0.1 g/cm3(Predicted) |
storage temp. | Inert atmosphere,Store in freezer, under -20°C |
solubility | Soluble in DMSO (up to 25 mg/ml) or in Water (up to 15 mg/ml with warming). |
form | solid |
pka | 8.19±0.20(Predicted) |
color | White |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months. |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
N(4)-hydroxycytidine price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
SRL | 54661 | N-Hydroxycytidine (EIDD-1931) for cell culture, 98%, Endotoxin (BET) 0.05EU/mg | 3258-02-4 | 10mg | ₹7000 | 2022-05-26 | Buy |
SRL | 54661 | N-Hydroxycytidine (EIDD-1931) for cell culture, 98%, Endotoxin (BET) 0.05EU/mg | 3258-02-4 | 25mg | ₹14000 | 2022-05-26 | Buy |
N(4)-hydroxycytidine Chemical Properties,Uses,Production
Description
EIDD-1931 is a ribonucleoside analog with antiviral activity. It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells, Middle East respiratory syndrome coronavirus (MERS-CoV) in Calu-3 2B4 cells, and SARS-CoV-2 in Vero cells (IC50s =0.1, 0.15 and 0.3 μM, respectively). It also reduces viral titers of Venezuelan equine encephalitis virus (VEEV) TC-83 in infected Vero cells (EC50 = 0.426 μM) and wild-type and remdesivir-resistant strains of the model CoV mouse hepatitis virus (MHV) in infected DBT cells. EIDD-1931 (100 and 400 mg/kg twice per day) reduces lung viral titers in mouse models of respiratory syncytial virus (RSV) and H1N1 influenza A virus infection.
Uses
EIDD 1931 is an orally bioavailable broad-spectrum antiviral that inhibits SARS-CoV-2 and other multiple endemic, epidemic and bat coronavirus and has the potential for seasonal and pandemic influenza treatment. A broad-spectrum ribonucleoside analog inhibitor of influenza and respiratory syncytial viruses.
N(4)-hydroxycytidine Preparation Products And Raw materials
Raw materials
Preparation Products
N(4)-hydroxycytidine Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | China | 3957 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21667 | 55 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | China | 13341 | 58 | Inquiry |
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