RESINIFERATOXIN

RESINIFERATOXIN Structure
CAS No.
57444-62-9
Chemical Name:
RESINIFERATOXIN
Synonyms
RTX;RESINIFERATOXIN;Resiniferatoxin >99%;Resiniferatoxin (80%);Resiniferatoxin, 98.5%;RESINIFERATOXIN,HIGHPURITY;DSDNAKHZNJAGHN-IHCAYWNCSA-N;RESINIFERATOXIN, 99%, HIGH PURITY;RESINIFERATOXIN,EUPHORBIA POISONII;RESINIFERATOXIN AUS EUPHORBIA POISONII
CBNumber:
CB7304594
Molecular Formula:
C37H40O9
Molecular Weight:
628.71
MOL File:
57444-62-9.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:40

RESINIFERATOXIN Properties

Boiling point 768.7±60.0 °C(Predicted)
Density 1.35±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in DMSO to 100mM and to 50mM in ethanol
form Solid
pka 9.85±0.20(Predicted)
color White to off-white
BRN 5371150
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS06
Signal word  Danger
Hazard statements  H315-H319-H335-H301-H314
Precautionary statements  P261-P280a-P301+P310a-P405-P501a-P280-P305+P351+P338-P310
Hazard Codes  T
Risk Statements  25-35
Safety Statements  26-36/37/39-45
RIDADR  UN 2928 6.1/PG 2
WGK Germany  3
RTECS  CY1633700
10-23
HazardClass  6.1(a)
PackingGroup  II
HS Code  29329990

RESINIFERATOXIN Chemical Properties,Uses,Production

Chemical Properties

white to off-white solid

Uses

Resiniferatoxin has been used as an agonist to transient receptor potential vanilloid 2 (TRPV2):

  • for complex preparation for cryo-electron microscopy structural studies
  • to test its effect towards immune responses to?P.?aeruginosa in sensory neurons associated with the cornea
  • to study its effects in the denervation of the peripheral sensory nerves in psoriatic mice

Hazard

A poison.

Biological Activity

Ultrapotent analog of capsaicin that is an agonist at vanilloid receptors (K i = 43 pM). Like capsaicin, it acts as a selective modulator of primary afferent neurons. Also available as part of the Vanilloid TRPV1 Receptor Tocriset™ .

RESINIFERATOXIN Preparation Products And Raw materials

RESINIFERATOXIN Suppliers

Global( 103)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Henan Alfa Chemical Co., Ltd +8618339805032 China 13141 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +8617865335152 China 10978 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +undefined18621343501 China 33350 58 Inquiry
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd +86-19164747840 +86-13119157289 China 2969 58 Inquiry
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 China 18018 56 Inquiry
Shanghai Zhiyun Biotechnology Co., Ltd 13119135307 China 2696 58 Inquiry
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 China 30968 58 Inquiry
RESINIFERATOXIN RESINIFERATOXIN,EUPHORBIA POISONII RESINIFERATOXIN FROM EUPHORBIA POISONII RESINIFERATOXIN AUS EUPHORBIA POISONII 4-Hydroxy-3-methoxy-[(2S,3aR,3bS,6aR,9aR,9bR,10R,11aR)-3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-8,10-dimethyl-11a-(] Resiniferatoxin,Euphorbiapoisonii,Highpurity RESINIFERATOXIN,HIGHPURITY RESINIFERATOXIN, 99%, HIGH PURITY 4-Hydroxy-3-methoxy-[(2S,3aR,3bS,6aR,9aR,9bR,10R,11aR)-3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-8,10-dimethyl-11alpha-(1-methylethenyl)-7-oxo-2-(phenylmethyl)-7H-2,9beta-epoxyazuleno[5,4-e]-1,3-benzodioxol-5-yl]benzeneacetate 6-O,7-Seco-5,6-dideoxy-6,7-didehydro-20-O-[(4-hydroxy-3-methoxyphenyl)acetyl]-21-dephenyl-21-benzyldaphnetoxin 4-Hydroxy-3-methoxy-[(2S,3aR,3bS,6aR,9aR,9bR,10R,11aR)-3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-8,10-dimethyl-11a-(1-methylethenyl)-7-oxo-2-(phenylmethyl)-7H-2,9b-epoxyazuleno[5,4-e]-1,3-benzodioxol-5-yl]benzeneacetate Resiniferatoxin >99% Resiniferatoxin (80%) DSDNAKHZNJAGHN-IHCAYWNCSA-N Resiniferatoxin, 98.5% Benzeneacetic acid, 4-hydroxy-3-methoxy-, [(2S,3aR,3bS,6aR,9aR,9bR,10R,11aR)-3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-8,10-dimethyl-11a-(1-methylethenyl)-7-oxo-2-(phenylmethyl)-7H-2,9b-epoxyazuleno[5,4-e]-1,3-benzodioxol-5-yl]methyl ester RTX 57444-62-9 5744-62-9 C37H40O9 Agonist Vanilloid/TRPV channel Ion Channels Vanilloids Neurobiology Pharmacologicals