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3,4-Dihydroxyphenylacetic acid

3,4-Dihydroxyphenylacetic acid Structure
CAS No.
102-32-9
Chemical Name:
3,4-Dihydroxyphenylacetic acid
Synonyms
2-(3,4-dihydroxyphenyl)acetic acid;DOPAC;3,4-Dihydroxybenzeneacetic acid;3,4-DihydroxyphenyL;HOMOPROTOCATECHUIC ACID;Dihydroxyphenylacetic acid;N,N-DIMETHYL-P-PHENYLENEDIAMINE SULFATE;ba2773;Ba 2773;dopaceticacid
CBNumber:
CB7358779
Molecular Formula:
C8H8O4
Molecular Weight:
168.15
MOL File:
102-32-9.mol
MSDS File:
SDS
Modify Date:
2023/11/16 17:07:08
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3,4-Dihydroxyphenylacetic acid Properties

Melting point 127-130 °C (lit.)
Boiling point 257.07°C (rough estimate)
Density 1.3037 (rough estimate)
refractive index 1.5090 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility water: soluble50mg/mL, clear, almost colorless
form Powder, Crystals or Lumps
pka 4.42±0.10(Predicted)
color White to off-white
Water Solubility Soluble in water and methanol.
BRN 2211017
InChI InChI=1S/C8H8O4/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)
InChIKey CFFZDZCDUFSOFZ-UHFFFAOYSA-N
SMILES C1(CC(O)=O)=CC=C(O)C(O)=C1
LogP 0.980
CAS DataBase Reference 102-32-9(CAS DataBase Reference)
NIST Chemistry Reference Acetic acid, (3,4-dihydroxyphenyl)-,(102-32-9)
EPA Substance Registry System 3,4-Dihydroxyphenylacetic acid (102-32-9)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  AH0590000
F  10-23
HS Code  29182900
NFPA 704
1
2 0

3,4-Dihydroxyphenylacetic acid price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) D1283 3,4-Dihydroxyphenylacetic Acid min. 98.0 % 102-32-9 25G ₹16000 2022-05-26 Buy
Product number Packaging Price Buy
D1283 25G ₹16000 Buy

3,4-Dihydroxyphenylacetic acid Chemical Properties,Uses,Production

Description

3,4-Dihydroxyphenylacetic acid (DOPAC) is a metabolite of the neurotransmitter dopamine. Dopamine can be metabolized into one of three substances. One such substance is DOPAC. Another is 3-methoxytyramine (3-MT). Both of these substances are degraded to form homovanillic acid (HVA). Both degradations involve the enzymes monoamine oxidase (MAO) and catechol-O-methyl transferase (COMT), albeit in reverse order: MAO catalyzes dopamine to DOPAC, and COMT catalyzes DOPAC to HVA; whereas COMT catalyzes dopamine to 3-MT and MAO catalyzes 3-MT to HVA. The third metabolic end-product of dopamine is norepinephrine (noradrenaline).
DOPAC can be oxidized by hydrogen peroxide, leading to the formation of toxic metabolites which destroy dopamine storage vesicles in the substantia nigra. This may contribute to the failure of levodopa treatment of Parkinson's disease. A MAO-B inhibitor such as selegiline or rasagiline can prevent this from happening.
wikipedia

Chemical Properties

beige to light brown crystalline powder

Uses

3,4-Dihydroxyphenylacetic Acid is a metabolite of Dopamine (D533782).

General Description

3,4-dihydroxyphenylacetic acid (DOPAC) is a normal constituent of rat brain tissue. A mass fragmentographic method for determination of DOPAC in rat brain tissue has been described. It is major metabolite of dopamine (DA). The voltammetric reduction of DOPAC has been studied at a glassy carbon electrode modified with single-wall carbon nanotubes (SWNTs). Semi-automatic fluorometric assay technique for DOPAC has been reported.

3,4-Dihydroxyphenylacetic acid Preparation Products And Raw materials

Raw materials

Hippuric acid Sodium acetate Acetic anhydride Hydrogen peroxide Benzene
Veratraldehyde Hydrochloric acid Sodium hydroxide Magnesium sulfate Sodium carbonate
3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid 3,4-Dihydroxyacetophenone Veratraldehyde cyanohydrin 2-hydroxy-3-(4-hydroxy-3-methoxy-phenyl)-propanoic acid 4-HYDROXY-3-NITROPHENYLACETIC ACID
(3,4-DIHYDROXYPHENYL)ACETONITRILE
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Preparation Products

Hydroxytyrosol 3,4-(METHYLENEDIOXY)PHENYLACETIC ACID 3,4-DIHYDROXYPHENYLACETAMIDE α,3,4-Tris[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetic Acid Methyl Ester

3,4-Dihydroxyphenylacetic acid Suppliers

Global( 303)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
REDDY N REDDY PHARMACEUTICALS +91-9848096759 +91-9848096759 Hyderabad, India 1989 58 Inquiry
BASR Fine Chemicals Pvt. Ltd. +91-9848230391 +91-9848230391 Telangana, India 908 58 Inquiry
BASR Fine Chemicals +91 40 2309 0147 New Delhi, India 237 56 Inquiry
Dhruvtara Chemicals Pvt. Ltd. 91 40 27154607 New Delhi, India 180 56 Inquiry
OCEAN TRADING CORPORATION +91(22) 24921669 New Delhi, India 6211 58 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
Supplier Advantage
REDDY N REDDY PHARMACEUTICALS 58
BASR Fine Chemicals Pvt. Ltd. 58
BASR Fine Chemicals 56
Dhruvtara Chemicals Pvt. Ltd. 56
OCEAN TRADING CORPORATION 58
CHEMSWORTH 30
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
TCI Chemicals (India) Pvt. Ltd. 58
Alfa Aesar 58

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3,4-Dihydroxyphenylacetic acid Spectrum

3,4-Dihydroxyphenylacetic acid(102-32-9)MS3,4-Dihydroxyphenylacetic acid(102-32-9)1HNMR3,4-Dihydroxyphenylacetic acid(102-32-9)13CNMR3,4-Dihydroxyphenylacetic acid(102-32-9)IR13,4-Dihydroxyphenylacetic acid(102-32-9)IR2

102-32-9(3,4-Dihydroxyphenylacetic acid)Related Search:

DL-3,4-DIHYDROXYMANDELIC ACID DL-4-HYDROXY-3-METHOXYMANDELIC ACID 3,4,5-Trimethoxyphenylacetic acid 4,5-DIMETHOXY-2-NITROPHENYLACETIC ACID ETHYL 3,4-DIMETHOXYPHENYLACETATE
METHYL HOMOVERATRATE 3-Hydroxy-4-methoxyphenylacetic acid 3,4-(METHYLENEDIOXY)PHENYLACETIC ACID 3,4-Diethoxyphenylacetic acid 3,5-DIMETHOXY-4-HYDROXYPHENYLACETIC ACID
2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID 2,3,4-TRIMETHOXYPHENYLACETIC ACID 3,4-Dihydroxyphenylacetic acid 1,3-BENZODIOXOLE-5-GLYCOLIC ACID Homovanillic acid
DL-4-HYDROXY-3-METHOXYMANDELIC ACID ETHYL HOMOVANILLATE 4-Ethoxy-3-methoxyphenylacetic acid
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Ba 2773 DIHYDROXYPHENYLACETIC ACID, 3,4-(RG) Dopac/(3,4-dihydroxyphenyl)-aceticaci Hypoxanthine DisodiuM (3,4-dihydroxyphenyl)-aceticaci 3,4-dihydroxy-benzeneaceticaci 3,4-dihydroxybenzeneaceticacid 3,4-Dihydroxyphenylacetic acid, 98+% 3,4-Dihydroxyphenylcaetic acid 3,4-DIHYDROXYPHENYLACETIC ACID, 97+% DOPAC, Homoprotocatechuic acid ba2773 Benzeneacetic acid, 3,4-dihydroxy- dihydroxyphenylaceticacid Dopacetic acid dopaceticacid PYROCATECHOL-4-ACETIC ACID CATECHOL-4-ACETIC ACID 4-CARBOXYMETHYLPYROCATECHOL 4-CARBOXYMETHYLCATECHOL 3,4-DIHYDROXYPHENYLACETIC ACID Catechol-p-acetic acid 4-Carboxymethylcatechol 4-Carboxymethylpyrocatechol Catechol-4-acetic Acid Homoprotocatechuic Acid Pyrocatechol-4-acetic Acid 3,4-Dihydroxyphenylacetic Acid > Mouse 3,4 dihydroxyphenylacetic acid elisa kit CAS 102-32-9 3, 4-Dihydroxybenzeneacetic Acid 3,4-Dihydroxybenzeneacetic acid 2-(3,4-dihydroxyphenyl)acetic acid Dihydroxyphenylacetic acid N,N-DIMETHYL-P-PHENYLENEDIAMINE SULFATE DOPAC HOMOPROTOCATECHUIC ACID 3,4-DihydroxyphenyL Senecionine Impurity 1 102-32-9 HO2C6H3CH2CO2H HOHOC6H3CH2COOH HO2C6H3CD2COOH C8 Carbonyl Compounds Carboxylic Acids Building Blocks Organic Building Blocks buildingblock Aromatic Phenylacetic Acids and Derivatives