ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Aromatic acids >Homovanillic acid
Homovanillic acid
- CAS No.
- 306-08-1
- Chemical Name:
- Homovanillic acid
- Synonyms
- HVA;Homovanilic acid;4-HYDROXY-3-METHOXYPHENYLACETIC ACID;4-Hydroxy-3-methoxybenzeneacetic acid;Benzeneacetic acid, 4-hydroxy-3-methoxy-;JACS-306-08-1;homovanillicaci;Vanilacetic acid;HOMOVANIUIC ACID;HOMORANILLIC ACID
- CBNumber:
- CB7198081
- Molecular Formula:
- C9H10O4
- Molecular Weight:
- 182.17
- MOL File:
- 306-08-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/10/16 17:43:51
| Melting point | 142-145 °C(lit.) |
|---|---|
| Boiling point | 235.56°C (rough estimate) |
| Density | 1.1634 (rough estimate) |
| refractive index | 1.4209 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Crystalline Powder |
| pka | 4.39±0.10(Predicted) |
| color | White to beige |
| Water Solubility | soluble |
| Merck | 14,4740 |
| BRN | 2213447 |
| Stability | Hygroscopic |
| LogP | 0.330 |
| CAS DataBase Reference | 306-08-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzeneacetic acid, 4-hydroxy-3-methoxy-(306-08-1) |
| EPA Substance Registry System | Homovanillic acid (306-08-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-23 | |||||||||
| TSCA | T | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29189900 | |||||||||
| NFPA 704 |
|
Homovanillic acid price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 69673 | Homovanillic acid analytical standard | 306-08-1 | 25MG | ₹6332.63 | 2022-06-14 | Buy |
| TCI Chemicals (India) | H0339 | 4-Hydroxy-3-methoxyphenylacetic Acid | 306-08-1 | 1G | ₹5200 | 2022-05-26 | Buy |
| ALFA India | ALF-A12441-14 | Homovanillic acid, 98+% | 306-08-1 | 25g | ₹28700 | 2022-05-26 | Buy |
| TCI Chemicals (India) | H0339 | 4-Hydroxy-3-methoxyphenylacetic Acid | 306-08-1 | 5G | ₹9800 | 2022-05-26 | Buy |
| ALFA India | ALF-A12441-06 | Homovanillic acid, 98+% | 306-08-1 | 5g | ₹10624 | 2022-05-26 | Buy |
Homovanillic acid Chemical Properties,Uses,Production
Description
Homovanillic acid (HVA) is a dopamine metabolite. It is formed via deamination of dopamine by monoamine oxidase (MAO) to produce 3,4-dihydroxyphenylacetic acid (DOPAC; ) followed by DOPAC metabolism by catechol-O-methyltransferase (COMT). HVA undergoes hydrogen peroxide-dependent oxidation in the presence of horseradish peroxidase to form a fluorescent dimer that displays excitation/emission maxima of 312/420 nm, respectively. It has been used to quantify hydrogen peroxide production in macrophages and neutrophils.
Chemical Properties
white to beige crystalline powder
Uses
Fluorimetric reagent and major catecholamine metaboliteHomovanillic acid is used as a reagent in the determination of oxidative enzymes. It is associated with dopamine levels in the brain. Its presence supports a diagnosis of neuroblastoma and malignant pheochromocytoma.
Definition
ChEBI: A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
Biological Activity
Fluorimetric reagent and major catecholamine metabolite. Used for fluorimetric determination of oxidative enzymes including glucose oxidase.
Homovanillic acid Preparation Products And Raw materials
Raw materials
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| Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
306-08-1(Homovanillic acid)Related Search:
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