ALPHA-HELICAL CRF (9-41)

ALPHA-HELICAL CRF (9-41) Structure
CAS No.
99658-03-4
Chemical Name:
ALPHA-HELICAL CRF (9-41)
Synonyms
ALPHA-HELICAL CRF (9-41);CORTICOTROPIN RELEASING FACTOR ANTAGONIST;α-Helical CRF (9-41) trifluoroacetate salt;ALPHA-HELICAL CORTICOTROPIN RELEASING FA CTOR;ALPHA-CORTICOTROPIN-RELEASING FACTOR 9-41, HELICAL;ALPHA-HELICAL CORTICOTROPIN RELEASING FACTOR (9-41);alpha-Helical corticotropin releasing factor fragment;α-helical corticotropin releasing factor fragment (9-41);ALPHA-HELICAL CORTICOTROPIN RELEASING FACTOR FRAGMENT (9-41);alpha-Helical CRF (9-41) |alpha|a-Helical Corticotropin Releasing Factor (9-41)
CBNumber:
CB1103870
Molecular Formula:
C22H25IN2O6
Molecular Weight:
540.34817
MOL File:
99658-03-4.mol
Modify Date:
2023/4/23 13:52:06

ALPHA-HELICAL CRF (9-41) Properties

storage temp. −20°C
form powder
color white

SAFETY

Risk and Safety Statements

WGK Germany  3

ALPHA-HELICAL CRF (9-41) price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C2917 Corticotropin Releasing Factor Antagonist ≥97% (HPLC) 99658-03-4 0.1MG ₹17482.38 2022-06-14 Buy
Product number Packaging Price Buy
C2917 0.1MG ₹17482.38 Buy

ALPHA-HELICAL CRF (9-41) Chemical Properties,Uses,Production

Biochem/physiol Actions

The corticotropin releasing factor (CRF) antagonist α-helical CRF [9-41] exhibits 10-fold higher affinity for rat CRF2α receptors over human CRF2α receptors. It has been used to elucidate the role of CRF in various physiological systems. In colonic epithelium, it abolishes CRF-induced changes in ion secretion, and significantly inhibits CRF-stimulated conductance. It antagonizes the CRF-induced proinflammatory degranulation of perivascular mast cells that are activated in response to acute psychological stress and CRF secretion.

ALPHA-HELICAL CRF (9-41) Preparation Products And Raw materials

Raw materials

Preparation Products

ALPHA-HELICAL CRF (9-41) Suppliers

Global( 48)Suppliers
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CORTICOTROPIN RELEASING FACTOR ANTAGONIST H-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-GLU-MET-LEU-GLU-MET-ALA-LYS-ALA-GLU-GLN-GLU-ALA-GLU-GLN-ALA-ALA-LEU-ASN-ARG-LEU-LEU-LEU-GLU-GLU-ALA-NH2 ASP-LEU-THR-PHE-HIS-LEU-ARG-GLU-MET-LEU-GLU-MET-ALA-LYS-ALA-GLU-GLN-ALA-GLU-GLN-ALA-LEU-ASN-ARG-LEU-LEU-GLU-ALA-NH2 ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-GLU-MET-LEU-GLU-MET-ALA-LYS-ALA-GLU-GLN-GLU-ALA-GLU-GLN-ALA-ALA-LEU-ASN-ARG-LEU-LEU-LEU-GLU-GLU-ALA-NH2 ALPHA-HELICAL CORTICOTROPIN RELEASING FA CTOR α-helical corticotropin releasing factor fragment (9-41) ALPHA-HELICAL CORTICOTROPIN RELEASING FACTOR (9-41) ALPHA-HELICAL CORTICOTROPIN RELEASING FACTOR FRAGMENT (9-41) ALPHA-HELICAL CRF (9-41) ALPHA-CORTICOTROPIN-RELEASING FACTOR 9-41, HELICAL alpha-Helical corticotropin releasing factor fragment methyl (2S)-2-[[(3R)-3-hydroxy-4-(phenylmethoxycarbonylamino)butanoyl]amino]-3-(2-iodophenyl)propanoate L-α-Aspartyl-L-leucyl-L-threonyl-L-phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-α-glutamyl-L-methionyl-L-leucyl-L-α-glutamyl-L-methionyl-L-alanyl-L-lysyl-L-alanyl-L-α-glutamyl-L-glutaminyl-L-α-glutamyl-L-alanyl-L-α-glutamyl-L-glutaminyl-L-alanyl-L-alanyl-L-leucyl-L-asparaginyl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-α-glutamyl-L-α-glutamyl-L-alanine α-Helical CRF (9-41) trifluoroacetate salt alpha-Helical CRF (9-41) |alpha|a-Helical Corticotropin Releasing Factor (9-41) 99658-03-4 C166H273N45O54S2 C22H25IN2O6 CRF Other Peptides Peptides Releasing Factors Biochemicals and Reagents BioChemical Amino Acids and Peptides CRF receptor and related