5-Nitro-2-pentanone
- CAS No.
- 22020-87-7
- Chemical Name:
- 5-Nitro-2-pentanone
- Synonyms
- 5-NITRO-2-PENTANONE;2-Pentanone, 5-nitro-;2-Pentanone, 5-nitro- (6CI,7CI,8CI,9CI)
- CBNumber:
- CB11082671
- Molecular Formula:
- C5H9NO3
- Molecular Weight:
- 131.13
- MOL File:
- 22020-87-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/1/31 13:54:48
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
5-Nitro-2-pentanone Chemical Properties,Uses,Production
Uses
5-Nitro-2-pentanone is used as an intermediate component in organic synthesis as a raw material for organic synthesis or in the preparation of pharmaceutical products.
Synthesis
5-Nitro-2-pentanone is prepared by the reaction of nitromethane and methyl vinyl ketone. The specific synthesis steps are as follows:
Methyl vinyl ketone (4. 17ml, 0.05 moles), nitromethane (24. 4ml, 0.45 moles) and THF (250ml) were mixed and stirred together under nitrogen. Potassium fluoride on alumina (lOg) was added and the mixture stirred for 2 hours at ambient temperature. The reaction was filtered and the filtrate was evaporated to give crude 5-nitro-2- pentanone as a pale yellow oil (6. 11g, 93%). Batches of crude 5-nitro-2-pentanone (total 29.7g) were combined and purified by vacuum distillation (bp 57-75°C/0. 3 mmHg) to give 5-nitro-2-pentanone as a pale yellow oil (17.7g, 60% recovery). 1H NMR (CDC13) 8 2.18 (s, 3H, CH3-CO), 2.25 (dt, 2H, CH2), 2.62 (t, 2H, CH2- CO), 4.44 (t, 2H, CH2-N02).
5-Nitro-2-pentanone Preparation Products And Raw materials
Raw materials
Preparation Products
5-Nitro-2-pentanone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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| WEIFANG OUCHEM TRADE CO.,LTD. | +86-18506360988 +86-18506360988 | China | 47 | 58 | Inquiry |
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| Shanghai Easy CDMO Co.,Ltd | 021-61734564 | China | 10010 | 58 | Inquiry |
| Waterstone Technology, LLC | 317 644 0862 | United States | 6801 | 30 | Inquiry |
| CHEMSTEP | 33 (0) 556 405 186 | Europe | 6144 | 51 | Inquiry |
| Shanghai Unibest Biopharma Co., Ltd. | 021-34621809 | China | 146 | 47 | Inquiry |
| APAC Pharmaceutical, LLC | +1(410) 997 5552 | United States | 6332 | 38 | Inquiry |
| Riedel-de Haen AG | 800 558-9160 | United States | 6825 | 87 | Inquiry |